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Information on EC 4.1.1.107 - 3,4-dihydroxyphenylacetaldehyde synthase

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EC Tree
     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.107 3,4-dihydroxyphenylacetaldehyde synthase
IUBMB Comments
A pyridoxal 5'-phosphate protein. The enzyme, isolated from the mosquito Aedes aegypti, catalyses the production of 3,4-dihydroxylphenylacetaldehyde directly from L-dopa. Dopamine is not formed as an intermediate (cf. EC 4.1.1.28, aromatic-L-amino-acid decarboxylase). The enzyme is specific for L-dopa and does not react with other aromatic amino acids with the exception of a low activity with alpha-methyl-L-dopa.
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The enzyme appears in viruses and cellular organisms
Synonyms
DHPA synthase, DHPAA synthase, EAT37246, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-dopa + O2 + H2O = 3,4-dihydroxyphenylacetaldehyde + CO2 + NH3 + H2O2
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PATHWAY SOURCE
PATHWAYS
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