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BRENDA support

Information on EC 3.7.1.18 - 6-oxocamphor hydrolase

for references in articles please use BRENDA:EC3.7.1.18

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IUBMB Comments

Isolated from Rhodococcus sp. The bornane ring system is cleaved by a retro-Claisen reaction to give the enol of α-campholonate. When separate from the enzyme the enol is tautomerised to the keto form as a 6:1 mixture of [(1S,3R)-2,2,3-trimethyl-4-oxocyclopentyl]acetate and [(1S,3S)-2,2,3-trimethyl-4-oxocyclopentyl]acetate.

The enzyme appears in viruses and cellular organisms

Synonyms
6-oxocamphor hydrolase, 6-oxo camphor hydrolase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
bornane-2,6-dione + H2O = [(1S)-4-hydroxy-2,2,3-trimethylcyclopent-3-enyl]acetate
show the reaction diagram
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