Reference on EC 3.5.1.B15 - pyrazinamidase and Organism(s) Mycobacterium tuberculosis and UniProt Accession I6XD65
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Rueda, D.; Sheen, P.; Gilman, R.H.; Bueno, C.; Santos, M.; Pando-Robles, V.; Batista, C.V.; Zimic, M.
Nicotinamidase/pyrazinamidase of Mycobacterium tuberculosis forms homo-dimers stabilized by disulfide bonds
Tuberculosis
94
644-648
2014
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis H37Rv (I6XD65)
Ramirez-Busby, S.M.; Valafar, F.
Systematic review of mutations in pyrazinamidase associated with pyrazinamide resistance in Mycobacterium tuberculosis clinical isolates
Antimicrob. Agents Chemother.
59
5267-5277
2015
Mycobacterium tuberculosis
Vats, C.; Dhanjal, J.; Goyal, S.; Gupta, A.; Bharadvaja, N.; Grover, A.
Mechanistic analysis elucidating the relationship between Lys96 mutation in Mycobacterium tuberculosis pyrazinamidase enzyme and pyrazinamide susceptibility
BMC Genomics
16(Suppl 2)
S14
2015
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis, Mycobacterium tuberculosis ATCC 25618 (I6XD65), Mycobacterium tuberculosis H37Rv (I6XD65)
Rasool, N.; Husssain, W.; Khan, Y.D.
Revelation of enzyme activity of mutant pyrazinamidases from Mycobacterium tuberculosis upon binding with various metals using quantum mechanical approach
Comput. Biol. Chem.
83
107108
2019
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis, Mycobacterium tuberculosis ATCC 25618 (I6XD65), Mycobacterium tuberculosis H37Rv (I6XD65)
Pazhang, M.; Mardi, N.; Mehrnejad, F.; Chaparzadeh, N.
The combinatorial effects of osmolytes and alcohols on the stability of pyrazinamidase methanol affects the enzyme stability through hydrophobic interactions and hydrogen bonds
Int. J. Biol. Macromol.
108
1339-1347
2018
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis, Mycobacterium tuberculosis ATCC 25618 (I6XD65), Mycobacterium tuberculosis H37Rv (I6XD65)
Khajehzadeh, M.; Mehrnejad, F.; Pazhang, M.; Doustdar, F.
Effects of sorbitol and glycerol on the structure, dynamics, and stability of Mycobacterium tuberculosis pyrazinamidase
Int. J. Mycobacteriol.
5 Suppl 1
S138-S139
2016
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis, Mycobacterium tuberculosis ATCC 25618 (I6XD65), Mycobacterium tuberculosis H37Rv (I6XD65)
Rueda, D.; Bernard, C.; Gandy, L.; Capton, E.; Boudjelloul, R.; Brossier, F.; Veziris, N.; Zimic, M.; Sougakoff, W.
Estimation of pyrazinamidase activity using a cell-free in vitro synthesis of pnca and its association with pyrazinamide susceptibility in Mycobacterium tuberculosis
Int. J. Mycobacteriol.
7
16-25
2018
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis, Mycobacterium tuberculosis ATCC 25618 (I6XD65), Mycobacterium tuberculosis H37Rv (I6XD65), Mycobacterium tuberculosis variant bovis
Khan, M.T.; Malik, S.I.
Structural dynamics behind variants in pyrazinamidase and pyrazinamide resistance
J. Biomol. Struct. Dyn.
38
3003-3017
2020
Mycobacterium tuberculosis (A0A2Z5CVM9), Mycobacterium tuberculosis
Esmaeeli, R.; Mehrnejad, F.; Mir-Derikvand, M.; Gopalpoor, N.
Computational insights into pH-dependence of structure and dynamics of pyrazinamidase A comparison of wild type and mutants
J. Cell. Biochem.
120
2502-2514
2018
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis ATCC 25618 (I6XD65), Mycobacterium tuberculosis H37Rv (I6XD65)
Khan, M.; Junaid, M.; Mao, X.; Wang, Y.; Hussain, A.; Malik, S.; Wei, D.
Pyrazinamide resistance and mutations L19R, R140H, and E144K in pyrazinamidase of Mycobacterium tuberculosis
J. Cell. Biochem.
120
7154-7166
2019
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis, Mycobacterium tuberculosis ATCC 25618 (I6XD65), Mycobacterium tuberculosis H37Rv (I6XD65)
Junaid, M.; Khan, M.T.; Malik, S.I.; Wei, D.Q.
Insights into the mechanisms of the pyrazinamide resistance of three pyrazinamidase mutants N11K, P69T, and D126N
J. Chem. Inf. Model.
59
498-508
2019
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis, Mycobacterium tuberculosis ATCC 25618 (I6XD65), Mycobacterium tuberculosis H37Rv (I6XD65)
Aono, A.; Chikamatsu, K.; Yamada, H.; Igarashi, Y.; Murase, Y.; Takaki, A.; Mitarai, S.
A simplified pyrazinamidase test for pyrazinamide drug susceptibility in Mycobacterium tuberculosis
J. Microbiol. Methods
154
52-54
2018
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis, Mycobacterium tuberculosis ATCC 25618 (I6XD65), Mycobacterium tuberculosis H37Rv (I6XD65)
Khadem-Maaref, M.; Mehrnejad, F.; Phirouznia, A.
Effects of metal-ion replacement on pyrazinamidase activity a quantum mechanical study
J. Mol. Graph. Model.
73
24-29
2017
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis ATCC 25618 (I6XD65), Mycobacterium tuberculosis H37Rv (I6XD65)
Rasool, N.; Iftikhar, S.; Amir, A.; Hussain, W.
Structural and quantum mechanical computations to elucidate the altered binding mechanism of metal and drug with pyrazinamidase from Mycobacterium tuberculosis due to mutagenicity
J. Mol. Graph. Model.
80
126-131
2018
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis, Mycobacterium tuberculosis ATCC 25618 (I6XD65), Mycobacterium tuberculosis H37Rv (I6XD65)
Doustdar, F.; Pazhang, M.; Mehrnejad, F.; Safarzadeh, M.; Rabiei, D.; Chaparzadeh, N.; Falahati, H.; Mir-Derikvand, M.
Biochemical characterization and computational identification of Mycobacterium tuberculosis pyrazinamidase in some pyrazinamide-resistant isolates of Iran
Protein J.
34
181-192
2015
Mycobacterium tuberculosis
Ahmadi, A.; Nazari, R.; Arjomandzadegan, M.; Zolfaghari, M.R.; Vahidi, V.; Poolad, T.; Kahbazi, M.; Sadrnia, M.; Tousheh, M.; Rafiee, P.
Insights into pyrazinamidase and DNA gyrase protein structures in resistant and susceptible clinical isolates of Mycobacterium tuberculosis
Tanaffos
15
147-153
2016
Mycobacterium tuberculosis (I6XD65), Mycobacterium tuberculosis, Mycobacterium tuberculosis ATCC 25618 (I6XD65), Mycobacterium tuberculosis H37Rv (I6XD65)
