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Synonyms
pzase, nicotinamidase, pnc-1, pnc1p, pzaase, nicotinamidase/pyrazinamidase, yndase, as87_01735, nicotinamidase pnc-1, na_as0847,
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Bacteremia
Intranasal immunization with pneumococcal polysaccharide conjugate vaccines with nontoxic mutants of Escherichia coli heat-labile enterotoxins as adjuvants protects mice against invasive pneumococcal infections.
Cysts
The NAD+ Responsive Transcription Factor ERM-BP Functions Downstream of Cellular Aggregation and Is an Early Regulator of Development and Heat Shock Response in Entamoeba.
Infections
A plasmid-encoded nicotinamidase (PncA) is essential for infectivity of Borrelia burgdorferi in a mammalian host.
Infections
Defining plasmids required by Borrelia burgdorferi for colonization of tick vector Ixodes scapularis (Acari: Ixodidae).
Leishmaniasis
In silico pharmacophore modeling and simulation studies for searching potent antileishmanials targeted against Leishmania donovani nicotinamidase.
Leprosy
Identification of cat leprosy bacillus grown in mice.
Neoplasms
Early effects of nicotinamide, 2,4-dichloro-phenoxy acetic acid & actinomycin-D on the synthesis of nicotinamide amidohydrolase in rumex acetosa tumour tissue.
Neuroblastoma
Purification and characterization of a nicotinamide deamidase released into the growth medium of neuroblastoma in vitro.
Photophobia
[Nicotinamidase and the so-called pyrazinamidase in mycobacteria; the simultaneous occurrence of both activites (author's transl)]
Pneumonia
Multiscale Computational Study on the Catalytic Mechanism of the Nonmetallo Amidase Maleamate Amidohydrolase (NicF).
Tuberculosis
A Multinational Analysis of Mutations and Heterogeneity in PZase, RpsA, and PanD Associated with Pyrazinamide Resistance in M/XDR Mycobacterium tuberculosis.
Tuberculosis
An assessment of a multiplex PCR assay for differentiating clinically important mycobacteria based on pncA gene variation.
Tuberculosis
Biochemical Characterization and Computational Identification of Mycobacterium tuberculosis Pyrazinamidase in Some Pyrazinamide-Resistant Isolates of Iran.
Tuberculosis
Characterization of Mycobacterium tuberculosis nicotinamidase/pyrazinamidase.
Tuberculosis
Characterization of pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis.
Tuberculosis
Characterization of pncA mutations of pyrazinamide-resistant Mycobacterium tuberculosis in Turkey.
Tuberculosis
Comparison of MGIT 960 & pyrazinamidase activity assay for pyrazinamide susceptibility testing of Mycobacterium tuberculosis.
Tuberculosis
Crystal structure and mechanism of catalysis of a pyrazinamidase from Pyrococcus horikoshii.
Tuberculosis
Crystal structure of the yeast nicotinamidase Pnc1p.
Tuberculosis
Cytochemical and biological properties of Mycobacterium bovis BCG.
Tuberculosis
Detection of Novel Gene Mutations Associated with Pyrazinamide Resistance in Multidrug-Resistant Mycobacterium tuberculosis Clinical Isolates in Southern China.
Tuberculosis
Direct Detection of Pyrazinamide Resistance in Mycobacterium tuberculosis by Use of pncA PCR Sequencing.
Tuberculosis
Effects of sorbitol and glycerol on the structure, dynamics, and stability of Mycobacterium tuberculosis pyrazinamidase.
Tuberculosis
Estimation of pyrazinamidase activity using a cell-free
Tuberculosis
Evaluation of drug susceptibility testing methods of clinical Mycobacterium tuberculosis isolates to pyrazinamide.
Tuberculosis
Extracellular enzyme activities potentially involved in the pathogenicity of Mycobacterium tuberculosis.
Tuberculosis
Identification, cloning, and expression of the Escherichia coli pyrazinamidase and nicotinamidase gene, pncA.
Tuberculosis
Insight to pyrazinamide resistance in Mycobacterium tuberculosis by molecular docking.
Tuberculosis
Kinetics and Inhibition of Nicotinamidase from Mycobacterium tuberculosis.
Tuberculosis
Mechanisms of pyrazinamide resistance in mycobacteria: importance of lack of uptake in addition to lack of pyrazinamidase activity.
Tuberculosis
Molecular characterization of pncA gene mutations in Mycobacterium tuberculosis clinical isolates from China.
Tuberculosis
Mutation in pncA is a major mechanism of pyrazinamide resistance in Mycobacterium tuberculosis.
Tuberculosis
Mutations in pncA, a gene encoding pyrazinamidase/nicotinamidase, cause resistance to the antituberculous drug pyrazinamide in tubercle bacillus.
Tuberculosis
Mycobacterium tuberculosis isolates from Rio de Janeiro reveal unusually low correlation between pyrazinamide resistance and mutations in the pncA gene.
Tuberculosis
Nicotinamidase/pyrazinamidase of Mycobacterium tuberculosis forms homo-dimers stabilized by disulfide bonds.
Tuberculosis
pncA mutations as a major mechanism of pyrazinamide resistance in Mycobacterium tuberculosis: spread of a monoresistant strain in Quebec, Canada.
Tuberculosis
pncA mutations in clinical Mycobacterium tuberculosis isolates from Korea.
Tuberculosis
Purification, gene cloning, targeted knockout, overexpression, and biochemical characterization of the major pyrazinamidase from Mycobacterium smegmatis.
Tuberculosis
Rapid colorimetric testing for pyrazinamide susceptibility of M. tuberculosis by a PCR-based in-vitro synthesized pyrazinamidase method.
Tuberculosis
Rapid detection of Mycobacterium tuberculosis and pyrazinamide susceptibility related to pncA mutations in sputum specimens through an integrated gene-to-protein function approach.
Tuberculosis
Rapid differentiation of bovine and human tubercle bacilli based on a characteristic mutation in the bovine pyrazinamidase gene.
Tuberculosis
Reduced pyrazinamidase activity and the natural resistance of Mycobacterium kansasii to the antituberculosis drug pyrazinamide.
Tuberculosis
Revelation of enzyme activity of mutant pyrazinamidases from Mycobacterium tuberculosis upon binding with various metals using quantum mechanical approach.
Tuberculosis
Specificity and Mechanism of Acinetobacter baumanii Nicotinamidase: Implications for Activation of the Front-Line Tuberculosis Drug Pyrazinamide.
Tuberculosis
Structural dynamics behind variants in pyrazinamidase and pyrazinamide resistance.
Tuberculosis
The curious characteristics of pyrazinamide: a review.
Tuberculosis
The paradox of pyrazinamide: an update on the molecular mechanisms of pyrazinamide resistance in Mycobacteria.
Tuberculosis
The pncA gene from naturally pyrazinamide-resistant Mycobacterium avium encodes pyrazinamidase and confers pyrazinamide susceptibility to resistant M. tuberculosis complex organisms.
Tuberculosis
[Type differentiation of tuberculosis bacteria with the aid of the nicotinamidase test.]
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