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Information on EC 3.4.24.64 - mitochondrial processing peptidase

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UNIPROT: Q10713 not found.
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
mitochondrial processing peptidase, beta-mpp, alpha-mpp, processing peptidase, matrix processing peptidase, atp23, mitochondrial processing protease, processing enhancing protein, general mitochondrial processing peptidase, pmpca, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
mitochondrial processing peptidase-alpha protein
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Alpha-MPP
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-
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Beta-MPP
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General mitochondrial processing peptidase
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HA1523
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Matrix peptidase
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Matrix processing peptidase
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Matrix processing proteinase
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Mitochondrial chelator-sensitive protease
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Mitochondrial protein precursor-processing proteinase
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MPP
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P-52
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P-55
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Processing enhancing peptidase
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Proteinase, mitochondrial protein precursor-processing
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of peptide bond
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CAS REGISTRY NUMBER
COMMENTARY hide
86280-61-7
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
Q10713: mitochondrial-processing peptidase subunit alpha
SwissProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
mutations in the substrate binding glycine-rich loop of the mitochondrial processing peptidase-alpha protein (PMPCA) cause a severe mitochondrial disease
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
MPPA_HUMAN
525
0
58253
Swiss-Prot
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Joshi, M.; Anselm, I.; Shi, J.; Bale, T.A.; Towne, M.; Schmitz-Abe, K.; Crowley, L.; Giani, F.C.; Kazerounian, S.; Markianos, K.; Lidov, H.G.; Folkerth, R.; Sankaran, V.G.; Agrawal, P.B.
Mutations in the substrate binding glycine-rich loop of the mitochondrial processing peptidase-alpha protein (PMPCA) cause a severe mitochondrial disease
Cold Spring Harb. Mol. Case Stud.
2
a000786
2016
Homo sapiens (Q10713), Homo sapiens
Manually annotated by BRENDA team