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Disease on EC 3.4.21.B60 - transmembrane protease serine 2 and Organism(s) Homo sapiens and UniProt Accession O15393

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acute Kidney Injury
Can transmembrane protease serine 2 be attributed to coronavirus disease-2019 related acute kidney injury predominance in males?
Novel Evidence of Acute Kidney Injury in COVID-19.
Acute Lung Injury
COVID-19-The Potential Beneficial Therapeutic Effects of Spironolactone during SARS-CoV-2 Infection.
Adenocarcinoma of Lung
Analysis of the susceptibility of lung cancer patients to SARS-CoV-2 infection.
Comparative Investigation of Composition, Antifungal, and Anti-Inflammatory Effects of the Essential Oil from Three Industrial Hemp Varieties from Italian Cultivation.
Structural variations and expression profiles of the SARS-CoV-2 host invasion genes in lung cancer.
Alopecia
Early Antiandrogen Therapy With Dutasteride Reduces Viral Shedding, Inflammatory Responses, and Time-to-Remission in Males With COVID-19: A Randomized, Double-Blind, Placebo-Controlled Interventional Trial (EAT-DUTA AndroCoV Trial - Biochemical).
Breast Neoplasms
Cross talk between COVID-19 and breast cancer.
Carcinogenesis
Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer.
Prevalence and clinical application of TMPRSS2-ERG fusion in Asian prostate cancer patients: a large-sample study in Chinese people and a systematic review.
Carcinoma
Analysis of the susceptibility of lung cancer patients to SARS-CoV-2 infection.
Cloning and characterization of the cDNA and gene for human epitheliasin.
Carcinoma, Squamous Cell
Analysis of the susceptibility of lung cancer patients to SARS-CoV-2 infection.
Structural variations and expression profiles of the SARS-CoV-2 host invasion genes in lung cancer.
Common Cold
Clinical Isolates of Human Coronavirus 229E Bypass the Endosome for Cell Entry.
Coronavirus Infections
A Review on Expression, Pathological Roles, and Inhibition of TMPRSS2, the Serine Protease Responsible for SARS-CoV-2 Spike Protein Activation.
COVID-19 and human reproduction: A pandemic that packs a serious punch.
Highlights in the fight against COVID-19: does autophagy play a role in SARS-CoV-2 infection?
The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S Protein-Mediated Fusion in a Cell Fusion Assay System and Viral Infection In Vitro in a Cell-Type-Dependent Manner.
COVID-19
Acute Pancreatitis in a Patient With COVID-19 After the Resolution of Respiratory Symptoms.
Airways Expression of SARS-CoV-2 Receptor, ACE2, and TMPRSS2 Is Lower in Children Than Adults and Increases with Smoking and COPD.
Alpha-1-antitrypsin: A possible host protective factor against Covid-19.
Association between SARS-CoV-2 infection and disease severity among prostate cancer patients on androgen deprivation therapy: a systematic review and meta-analysis.
Cellular Tropism of SARS-CoV-2 across Human Tissues and Age-related Expression of ACE2 and TMPRSS2 in Immune-inflammatory Stromal Cells.
Characteristics of Angiotensin I-converting enzyme 2, type II transmembrane serine protease 2 and 4 in tree shrew indicate it as a potential animal model for SARS-CoV-2 infection.
Classical and alternative receptors for SARS-CoV-2 therapeutic strategy.
Cognitive disorders associated with hospitalization of COVID-19: Results from an observational cohort study.
Comprehensive analysis of two potential novel SARS-CoV-2 entries, TMPRSS2 and IFITM3, in healthy individuals and cancer patients.
COVID-19 and human reproduction: A pandemic that packs a serious punch.
COVID-19-The Potential Beneficial Therapeutic Effects of Spironolactone during SARS-CoV-2 Infection.
COVID-19: Understanding Inter-Individual Variability and Implications for Precision Medicine.
Cross talk between COVID-19 and breast cancer.
Dealing with lung cancer in the COVID-19 scenario (A review).
Differential Expression of Rab5 and Rab7 Small GTPase Proteins in Placental Tissues From Pregnancies Affected by Maternal Coronavirus Disease 2019.
Do Anti-androgens Have Potential as Therapeutics for COVID-19?
Does severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) cause orchitis in patients with coronavirus disease 2019 (COVID-19)?
Early Antiandrogen Therapy With Dutasteride Reduces Viral Shedding, Inflammatory Responses, and Time-to-Remission in Males With COVID-19: A Randomized, Double-Blind, Placebo-Controlled Interventional Trial (EAT-DUTA AndroCoV Trial - Biochemical).
Effect of bromhexine in hospitalized patients with COVID-19.
Estrogen receptors are linked to angiotensin-converting enzyme 2 (ACE2), ADAM metallopeptidase domain 17 (ADAM-17), and transmembrane protease serine 2 (TMPRSS2) expression in the human atrium: insights into COVID-19.
Existence of SARS-CoV-2 Entry Molecules in the Oral Cavity.
Expression of Endogenous Angiotensin-Converting Enzyme 2 in Human Induced Pluripotent Stem Cell-Derived Retinal Organoids.
From bedside to bench: regulation of host factors in SARS-CoV-2 infection.
Gastrointestinal cancers, ACE-2/TMPRSS2 expression and susceptibility to COVID-19.
GB-2 inhibits ACE2 and TMPRSS2 expression: In vivo and in vitro studies.
Gene expression network analysis provides potential targets against SARS-CoV-2.
Highlights in the fight against COVID-19: does autophagy play a role in SARS-CoV-2 infection?
Human genetic basis of coronavirus disease 2019.
Impact of COVID-19 on the Endocrine System - a mini-review.
Integrative analysis of miRNA and mRNA sequencing data reveals potential regulatory mechanisms of ACE2 and TMPRSS2.
Is There a Link between Bisphenol A (BPA), a Key Endocrine Disruptor, and the Risk for SARS-CoV-2 Infection and Severe COVID-19?
Low risk of the TMPRSS2 inhibitor camostat mesylate and its metabolite GBPA to act as perpetrators of drug-drug interactions.
Male balding as a major risk factor for severe COVID-19: a possible role for targeting androgens and transmembrane protease serine 2 to protect vulnerable individuals.
Mechanics Insights of Alpha-Lipoic Acid against Cardiovascular Diseases during COVID-19 Infection.
No evidence of severe acute respiratory syndrome-coronavirus 2 in semen of males recovering from coronavirus disease 2019.
Paediatric COVID-19 and the GUT.
Pan?cancer analysis of transmembrane protease serine 2 and cathepsin L that mediate cellular SARS?CoV?2 infection leading to COVID-19.
Pandemic COVID-19 caused by SARS-CoV-2: genetic structure, vaccination, and therapeutic approaches.
Pernio (Chilblains), SARS-CoV-2, and COVID Toes Unified Through Cutaneous and Systemic Mechanisms.
Phyto-pharmacological perspective of Silymarin: A potential prophylactic or therapeutic agent for COVID-19, based on its promising immunomodulatory, anti-coagulant and anti-viral property.
Platycodin D, a natural component of Platycodon grandiflorum, prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection by hindering membrane fusion.
Possible use of the mucolytic drug, bromhexine hydrochloride, as a prophylactic agent against SARS-CoV-2 infection based on its action on the Transmembrane Serine Protease 2.
Questionnaire Survey on the Current Situation and Experience in Prevention and Control Measures at Urology Clinics During the COVID-19 Epidemic in China.
Roles of existing drug and drug targets for COVID-19 management.
SARS-CoV-2 entry inhibitors by dual targeting TMPRSS2 and ACE2: An in silico drug repurposing study.
SARS-CoV-2 infection and smoking: What is the association? A brief review.
Stress Decreases Host Viral Resistance and Increases Covid Susceptibility in Embryonic Stem Cells.
Strong Correlation between the Case Fatality Rate of COVID-19 and the rs6598045 Single Nucleotide Polymorphism (SNP) of the Interferon-Induced Transmembrane Protein 3 (IFITM3) Gene at the Population-Level.
Targeting transcriptional regulation of SARS-CoV-2 entry factors ACE2 and TMPRSS2.
Testosterone target therapy: focus on immune response, controversies and clinical implications in patients with COVID-19 infection.
The contrasting role of nasopharyngeal angiotensin converting enzyme 2 (ACE2) transcription in SARS-CoV-2 infection: A cross-sectional study of people tested for COVID-19 in British Columbia, Canada.
The role of androgens in COVID-19.
Type 2 inflammation modulates ACE2 and TMPRSS2 in airway epithelial cells.
Understanding structural malleability of the SARS-CoV-2 proteins and relation to the comorbidities.
Unravelling high-affinity binding compounds towards transmembrane protease serine 2 enzyme in treating SARS-CoV-2 infection using molecular modelling and docking studies.
White Button Mushroom (Agaricus bisporus) Interrupts Tissue AR-TMPRSS2 Expression and Attenuates Pro-inflammatory Cytokines in C57BL/6 Mice: Implication for COVID-19 Dietary Intervention.
Why does SARS-CoV-2 hit in different ways? Host genetic factors can influence the acquisition or the course of COVID-19.
Why is COVID-19 less severe in children? A review of the proposed mechanisms underlying the age-related difference in severity of SARS-CoV-2 infections.
Cystic Fibrosis
SARS-CoV-2 Entry Genes Expression in Relation with Interferon Response in Cystic Fibrosis Patients.
Cytomegalovirus Infections
Why is COVID-19 less severe in children? A review of the proposed mechanisms underlying the age-related difference in severity of SARS-CoV-2 infections.
Disseminated Intravascular Coagulation
The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S Protein-Mediated Fusion in a Cell Fusion Assay System and Viral Infection In Vitro in a Cell-Type-Dependent Manner.
Hepatitis
Highlights in the fight against COVID-19: does autophagy play a role in SARS-CoV-2 infection?
Infections
A Cytopathic Effect-Based Tissue Culture Method for HCoV-OC43 Titration Using TMPRSS2-Expressing VeroE6 Cells.
Alpha-1 Antitrypsin for COVID-19 Treatment: Dual Role in Antiviral Infection and Anti-Inflammation.
Can SARS-CoV-2 infect the eye? An overview of the receptor status in ocular tissue.
Cognitive disorders associated with hospitalization of COVID-19: Results from an observational cohort study.
COVID-19 and bronchial asthma: current perspectives.
COVID-19-The Potential Beneficial Therapeutic Effects of Spironolactone during SARS-CoV-2 Infection.
Do Anti-androgens Have Potential as Therapeutics for COVID-19?
Effect of bromhexine in hospitalized patients with COVID-19.
Efficient activation of SARS coronavirus spike protein by the transmembrane protease, TMPRSS2.
Expression of severe acute respiratory syndrome coronavirus 2 cell entry genes, angiotensin-converting enzyme 2 and transmembrane protease serine 2, in the placenta across gestation and at the maternal-fetal interface in pregnancies complicated by preterm birth or preeclampsia.
Human eggs, zygotes, and embryos express the receptor angiotensin 1-converting enzyme 2 and transmembrane serine protease 2 protein necessary for severe acute respiratory syndrome coronavirus 2 infection.
Integrative analysis of miRNA and mRNA sequencing data reveals potential regulatory mechanisms of ACE2 and TMPRSS2.
Pan?cancer analysis of transmembrane protease serine 2 and cathepsin L that mediate cellular SARS?CoV?2 infection leading to COVID-19.
Pernio (Chilblains), SARS-CoV-2, and COVID Toes Unified Through Cutaneous and Systemic Mechanisms.
Potential repurposing of the HDAC inhibitor valproic acid for patients with COVID-19.
Role of Structural and Non-Structural Proteins and Therapeutic Targets of SARS-CoV-2 for COVID-19.
Roles of existing drug and drug targets for COVID-19 management.
SARS-CoV-2 pseudovirus infectivity and expression of viral entry-related factors ACE2, TMPRSS2, Kim-1, and NRP-1 in human cells from the respiratory, urinary, digestive, reproductive, and immune systems.
The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S Protein-Mediated Fusion in a Cell Fusion Assay System and Viral Infection In Vitro in a Cell-Type-Dependent Manner.
Transmembrane serine protease 2 Polymorphisms and Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Type 2 Infection: A German Case-Control Study.
[Can SARS-CoV-2 infect the eye?-An overview of the receptor status in ocular tissue].
Influenza in Birds
Establishment of MDCK Stable Cell Lines Expressing TMPRSS2 and MSPL and Their Applications in Propagating Influenza Vaccine Viruses in Absence of Exogenous Trypsin.
Influenza, Human
Airway proteases: an emerging drug target for influenza and other respiratory virus infections.
Effect of bromhexine in hospitalized patients with COVID-19.
Influenza virus activating host proteases: Identification, localization and inhibitors as potential therapeutics.
The human Transmembrane Protease Serine 2 is necessary for the production of Group 2 influenza A virus pseudotypes.
White button mushroom interrupts tissue AR-mediated TMPRSS2 expression and attenuates pro-inflammatory cytokines in C57BL/6 mice.
Liver Diseases
Single-Cell RNA-seq Reveals Angiotensin-Converting Enzyme 2 and Transmembrane Serine Protease 2 Expression in TROP2+ Liver Progenitor Cells: Implications in Coronavirus Disease 2019-Associated Liver Dysfunction.
Neoplasm Metastasis
Targeting the intestinal TMPRSS2 protease to prevent SARS-CoV-2 entry into enterocytes-prospects and challenges.
Neoplasms
A pressor dose of angiotensin II has no influence on the angiotensin-converting enzyme 2 and other molecules associated with SARS-CoV-2 infection in mice.
Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer.
ACE2 and TMPRSS2 Potential Involvement in Genetic Susceptibility to SARS-COV-2 in Cancer Patients.
Distinct prostate cancer-related mRNA cargo in extracellular vesicle subsets from prostate cell lines.
Downregulation of ACE2 expression by SARS-CoV-2 worsens the prognosis of KIRC and KIRP patients via metabolism and immunoregulation.
Genetic Susceptibility of ACE2 and TMPRSS2 in Six Common Cancers and Possible Impacts on COVID-19.
Highlights in the fight against COVID-19: does autophagy play a role in SARS-CoV-2 infection?
Micro-RNA-204 Participates in TMPRSS2/ERG Regulation and Androgen Receptor Reprogramming in Prostate Cancer.
Potential detrimental role of soluble ACE2 in severe COVID-19 comorbid patients.
Saccharomyces cerevisiae-like 1 overexpression is frequent in prostate cancer and has markedly different effects in Ets-related gene fusion-positive and fusion-negative cancers.
Targeted Next-generation Sequencing of Advanced Prostate Cancer Identifies Potential Therapeutic Targets and Disease Heterogeneity.
Targeting the intestinal TMPRSS2 protease to prevent SARS-CoV-2 entry into enterocytes-prospects and challenges.
The role of T2E mediated CBF-1/RBP-J? signaling in metastatic thyroid cancer.
TMPRSS2-ERG Fusion Promotes Recruitment of Regulatory T cells and Tumor Growth in Prostate Cancer.
TMPRSS2-ERG Status in Circulating Tumor Cells as a Predictive Biomarker of Sensitivity in Castration-Resistant Prostate Cancer Patients Treated With Abiraterone Acetate.
Neoplastic Cells, Circulating
TMPRSS2-ERG Status in Circulating Tumor Cells as a Predictive Biomarker of Sensitivity in Castration-Resistant Prostate Cancer Patients Treated With Abiraterone Acetate.
Paramyxoviridae Infections
Effect of bromhexine in hospitalized patients with COVID-19.
Periodontal Pocket
Role of NLRP3 inflammasome in COVID-19 and periodontitis: Possible protective effect of melatonin.
Pneumonia
COVID-19-The Potential Beneficial Therapeutic Effects of Spironolactone during SARS-CoV-2 Infection.
Pre-Eclampsia
Expression of severe acute respiratory syndrome coronavirus 2 cell entry genes, angiotensin-converting enzyme 2 and transmembrane protease serine 2, in the placenta across gestation and at the maternal-fetal interface in pregnancies complicated by preterm birth or preeclampsia.
Premature Birth
Expression of severe acute respiratory syndrome coronavirus 2 cell entry genes, angiotensin-converting enzyme 2 and transmembrane protease serine 2, in the placenta across gestation and at the maternal-fetal interface in pregnancies complicated by preterm birth or preeclampsia.
Prostatic Neoplasms
Androgen receptor and gene network: Micromechanics reassemble the signaling machinery of TMPRSS2-ERG positive prostate cancer cells.
Antibody-independent targeted quantification of TMPRSS2-ERG fusion protein products in prostate cancer.
Assessment of long-term outcomes associated with urinary prostate cancer antigen 3 and TMPRSS2:ERG gene fusion at repeat biopsy.
Clinical significance of ERG rearrangement subtype and its association with increased p53 expression in Japanese and German prostate cancer.
Comparative assessment of urinary prostate cancer antigen 3 and TMPRSS2:ERG gene fusion with the serum [-2]proprostate-specific antigen-based prostate health index for detection of prostate cancer.
Correlation of urine TMPRSS2:ERG and PCA3 to ERG+ and total prostate cancer burden.
Distinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide.
ERG expression in prostate cancer: biological relevance and clinical implication.
ERG immunohistochemistry is not predictive for PSA recurrence, local recurrence or overall survival after radical prostatectomy for prostate cancer.
ERG oncoprotein expression in prostate carcinoma patients of different ethnicities.
ERG-TMPRSS2 rearrangement is shared by concurrent prostatic adenocarcinoma and prostatic small cell carcinoma and absent in small cell carcinoma of the urinary bladder: evidence supporting monoclonal origin.
Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer.
ETS Gene Fusions in Prostate Cancer: From Discovery to Daily Clinical Practice.
Expression of the Androgen-Regulated Fusion Gene TMPRSS2-ERG Does Not Predict Response to Endocrine Treatment in Hormone-Naïve, Node-Positive Prostate Cancer.
High concordance of TMPRSS-ERG fusion between primary prostate cancer and its lymph node metastases.
Management of men with previous negative prostate biopsy.
Obesity and Prostate Cancer Risk According to Tumor TMPRSS2:ERG Gene Fusion Status.
Phosphorylation of the oncogenic transcription factor ERG in prostate cells dissociates polycomb repressive complex 2 allowing target gene activation.
Prevalence and clinical application of TMPRSS2-ERG fusion in Asian prostate cancer patients: a large-sample study in Chinese people and a systematic review.
Prostate cancer proteomics: Current trends and future perspectives for biomarker discovery.
T2E (TMPRSS2-ERG) fusion transcripts are associated with higher levels of AMACR mRNA and a subsequent prostate cancer diagnosis in patients with atypical small acinar proliferation.
The discovery and application of gene fusions in prostate cancer.
The discovery of common recurrent transmembrane protease serine 2 (TMPRSS2)-erythroblastosis virus E26 transforming sequence (ETS) gene fusions in prostate cancer: significance and clinical implications.
The Significance of ERG and Androgen Receptor Expression in Adenocarcinoma Prostate.
The TMPRSS2:ERG Rearrangement, ERG Expression, and Prostate Cancer Outcomes: A Cohort Study and Meta-analysis.
TMPRSS2-ERG Fusion Gene Expression in Prostate Tumor Cells and Its Clinical and Biological Significance in Prostate Cancer Progression.
TMPRSS2-ERG Fusion Promotes Recruitment of Regulatory T cells and Tumor Growth in Prostate Cancer.
TMPRSS2-ERG Fusions Are Strongly Linked to Young Patient Age in Low-grade Prostate Cancer.
TMPRSS2-ERG gene fusion in Turkish patients with localized prostate cancer: results of radical prostatectomy specimens.
TMPRSS2-ERG gene fusions induce prostate tumorigenesis by modulating microRNA miR-200c.
TRANSMEMBRANE PROTEASE SERINE 2 IN PROSTATE CANCER.
Urine TMPRSS2:ERG Fusion Transcript Stratifies Prostate Cancer Risk in Men with Elevated Serum PSA.
White Button Mushroom (Agaricus bisporus) Interrupts Tissue AR-TMPRSS2 Expression and Attenuates Pro-inflammatory Cytokines in C57BL/6 Mice: Implication for COVID-19 Dietary Intervention.
White button mushroom interrupts tissue AR-mediated TMPRSS2 expression and attenuates pro-inflammatory cytokines in C57BL/6 mice.
[Frequency and transcript variant analysis of gene fusions between TMPRSS2 and ETS transcription factor genes in prostate cancer]
[The progress of TMPRSS2-ETS gene fusions and their mechanism in prostate cancer].
Renal Insufficiency, Chronic
Kidney ACE2 expression: Implications for chronic kidney disease.
Retinoblastoma
Targeted Next-generation Sequencing of Advanced Prostate Cancer Identifies Potential Therapeutic Targets and Disease Heterogeneity.
Severe Acute Respiratory Syndrome
A Review on Expression, Pathological Roles, and Inhibition of TMPRSS2, the Serine Protease Responsible for SARS-CoV-2 Spike Protein Activation.
Airways Expression of SARS-CoV-2 Receptor, ACE2, and TMPRSS2 Is Lower in Children Than Adults and Increases with Smoking and COPD.
Alpha-1 Antitrypsin for COVID-19 Treatment: Dual Role in Antiviral Infection and Anti-Inflammation.
Camostat Mesylate May Reduce Severity of Coronavirus Disease 2019 Sepsis: A First Observation.
Circulating Soluble ACE2 and Upstream microRNA Expressions in Serum of Type 2 Diabetes Mellitus Patients.
Cognitive disorders associated with hospitalization of COVID-19: Results from an observational cohort study.
COVID-19 and bronchial asthma: current perspectives.
COVID-19 and human reproduction: A pandemic that packs a serious punch.
COVID-19: Understanding Inter-Individual Variability and Implications for Precision Medicine.
Diesel Particulate Matter 2.5 Induces Epithelial-to-Mesenchymal Transition and Upregulation of SARS-CoV-2 Receptor during Human Pluripotent Stem Cell-Derived Alveolar Organoid Development.
Do Anti-androgens Have Potential as Therapeutics for COVID-19?
Does severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) cause orchitis in patients with coronavirus disease 2019 (COVID-19)?
Downregulation of ACE2 expression by SARS-CoV-2 worsens the prognosis of KIRC and KIRP patients via metabolism and immunoregulation.
Early Antiandrogen Therapy With Dutasteride Reduces Viral Shedding, Inflammatory Responses, and Time-to-Remission in Males With COVID-19: A Randomized, Double-Blind, Placebo-Controlled Interventional Trial (EAT-DUTA AndroCoV Trial - Biochemical).
Estrogen and Androgen Receptor Inhibitors: Unexpected Allies in the Fight Against COVID-19.
Existence of SARS-CoV-2 Entry Molecules in the Oral Cavity.
Expression of ACE2, TMPRSS2, and Furin in Mouse Ear Tissue, and the Implications for SARS-CoV-2 Infection.
Expression of severe acute respiratory syndrome coronavirus 2 cell entry genes, angiotensin-converting enzyme 2 and transmembrane protease serine 2, in the placenta across gestation and at the maternal-fetal interface in pregnancies complicated by preterm birth or preeclampsia.
Hesperidin Is a Potential Inhibitor against SARS-CoV-2 Infection.
Highlights in the fight against COVID-19: does autophagy play a role in SARS-CoV-2 infection?
Human eggs, zygotes, and embryos express the receptor angiotensin 1-converting enzyme 2 and transmembrane serine protease 2 protein necessary for severe acute respiratory syndrome coronavirus 2 infection.
Kidney ACE2 expression: Implications for chronic kidney disease.
Micronutrients and bioactive substances: Their potential roles in combating COVID-19.
miR-98 Regulates TMPRSS2 Expression in Human Endothelial Cells: Key Implications for COVID-19.
No evidence of severe acute respiratory syndrome-coronavirus 2 in semen of males recovering from coronavirus disease 2019.
Paediatric COVID-19 and the GUT.
Pernio (Chilblains), SARS-CoV-2, and COVID Toes Unified Through Cutaneous and Systemic Mechanisms.
SARS-CoV-2 pseudovirus infectivity and expression of viral entry-related factors ACE2, TMPRSS2, Kim-1, and NRP-1 in human cells from the respiratory, urinary, digestive, reproductive, and immune systems.
Sex Hormones and Hormone Therapy during COVID-19 Pandemic: Implications for Patients with Cancer.
Spironolactone may provide protection from SARS-CoV-2: Targeting androgens, angiotensin converting enzyme 2 (ACE2), and renin-angiotensin-aldosterone system (RAAS).
Targeting transcriptional regulation of SARS-CoV-2 entry factors ACE2 and TMPRSS2.
TMPRSS11D and TMPRSS13 Activate the SARS-CoV-2 Spike Protein.
Transmembrane serine protease 2 Polymorphisms and Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Type 2 Infection: A German Case-Control Study.
Viremia
An Update on Coronavirus Disease 2019 (COVID-19) and Pregnancy.
Assessment of Maternal and Neonatal SARS-CoV-2 Viral Load, Transplacental Antibody Transfer, and Placental Pathology in Pregnancies During the COVID-19 Pandemic.
Virus Diseases
Dodging COVID-19 infection: low expression and localization of ACE2 and TMPRSS2 in multiple donor-derived lines of human umbilical cord-derived mesenchymal stem cells.
Targeting the intestinal TMPRSS2 protease to prevent SARS-CoV-2 entry into enterocytes-prospects and challenges.