Disease on EC 3.4.21.B42 - hippostasin
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Adenocarcinoma
KLK11 mRNA expression predicts poor disease-free and overall survival in colorectal adenocarcinoma patients.
Adenoma
Human kallikrein gene 11 (KLK11) mRNA overexpression is associated with poor prognosis in patients with epithelial ovarian cancer.
beta-Thalassemia
Demonstration of kallikrein-like protease activity in nonactivated plasma of patients with Cooley's anemia.
Brain Neoplasms
Immunoreactivity, ultrastructural localization, and transcript expression of prostate-specific antigen in human neuroblastoma cell lines.
Breast Neoplasms
Bioregulation of kallikrein-related peptidases 6, 10 and 11 by the kinin B? receptor in breast cancer cells.
Breast Neoplasms
Intracellular signaling pathways regulate hormone-dependent kallikrein gene expression.
Breast Neoplasms
Kallikrein 11 expressed in human breast cancer cells releases insulin-like growth factor through degradation of IGFBP-3.
Breast Neoplasms
Novel Biomarkers Aim at Detecting Metastatic Sentinel Lymph Nodes in Breast Cancer
Carcinogenesis
KLK11 suppresses cellular proliferation via inhibition of Wnt/?-catenin signaling pathway in esophageal squamous cell carcinoma.
Carcinoma
Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types.
Carcinoma
Favorable prognostic value of tissue human kallikrein 11 (hK11) in patients with ovarian carcinoma.
Carcinoma
Human kallikrein gene 11 (KLK11) mRNA overexpression is associated with poor prognosis in patients with epithelial ovarian cancer.
Carcinoma
KLK11 acts as a tumor-inhibitor in laryngeal squamous cell carcinoma through the inactivation of Akt/Wnt/?-catenin signaling.
Carcinoma
KLK11 suppresses cellular proliferation via inhibition of Wnt/?-catenin signaling pathway in esophageal squamous cell carcinoma.
Carcinoma
Over-expression of human kallikrein 11 is associated with poor prognosis in patients with low rectal carcinoma.
Carcinoma
Prognostic significance of human tissue kallikrein-related peptidases 11 and 15 in gastric cancer.
Carcinoma
Validation and characterization of human kallikrein 11 as a serum marker for diagnosis of ovarian carcinoma.
Carcinoma, Hepatocellular
Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types.
Carcinoma, Non-Small-Cell Lung
Is Human Kallikrein 11 in Non-small Cell Lung Cancer Treated Chemoradiotherapy Associated with Survival?
Carcinoma, Renal Cell
Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types.
Cardiomegaly
KLK11 promotes the activation of mTOR and protein synthesis to facilitate cardiac hypertrophy.
Colonic Neoplasms
The use of kallikrein-related peptidases as adjuvant prognostic markers in colorectal cancer.
Colorectal Neoplasms
KLK11 mRNA expression predicts poor disease-free and overall survival in colorectal adenocarcinoma patients.
Colorectal Neoplasms
Knockdown of KLK11 inhibits cell proliferation and increases oxaliplatin sensitivity in human colorectal cancer.
Colorectal Neoplasms
Knockdown of KLK11 reverses oxaliplatin resistance by inhibiting proliferation and activating apoptosis via suppressing the PI3K/AKT signal pathway in colorectal cancer cell.
Dermatitis, Atopic
Human tissue kallikrein expression in the stratum corneum and serum of atopic dermatitis patients.
Dry Eye Syndromes
Elevated Immunoglobulin to Tissue KLK11 in Patients With Sjögren Syndrome.
Esophageal Squamous Cell Carcinoma
KLK11 suppresses cellular proliferation via inhibition of Wnt/?-catenin signaling pathway in esophageal squamous cell carcinoma.
hippostasin deficiency
KLK11 suppresses cellular proliferation via inhibition of Wnt/?-catenin signaling pathway in esophageal squamous cell carcinoma.
Laryngeal Neoplasms
Diagnostic and prognostic significance of human kallikrein 11 (KLK11) mRNA expression levels in patients with laryngeal cancer.
Lung Neoplasms
Expression of the human kallikrein genes 10 (KLK10) and 11 (KLK11) in cancerous and non-cancerous lung tissues.
Lung Neoplasms
Is Human Kallikrein 11 in Non-small Cell Lung Cancer Treated Chemoradiotherapy Associated with Survival?
Lymphatic Metastasis
Kallikrein-11, in Association with Coiled-Coil Domain Containing 25, as a Potential Prognostic Marker for Cholangiocarcinoma with Lymph Node Metastasis.
Lymphatic Metastasis
Prognostic significance of human tissue kallikrein-related peptidases 11 and 15 in gastric cancer.
Mesothelioma
Global Gene Expression Profiling of Pleural Mesotheliomas: Overexpression of Aurora Kinases and P16/CDKN2A Deletion as Prognostic Factors and Critical Evaluation of Microarray-Based Prognostic Prediction.
Nasopharyngeal Carcinoma
Diagnostic and prognostic values of KLK11 in nasopharyngeal carcinoma.
Neoplasm Metastasis
Development of a survival prediction model for gastric cancer using serine proteases and their inhibitors.
Neoplasm Metastasis
Identification and validation of Kallikrein-ralated peptidase 11 as a novel prognostic marker of gastric cancer based on immunohistochemistry.
Neoplasm Metastasis
Kallikrein-11, in Association with Coiled-Coil Domain Containing 25, as a Potential Prognostic Marker for Cholangiocarcinoma with Lymph Node Metastasis.
Neoplasm Metastasis
Prognostic significance of human tissue kallikrein-related peptidases 11 and 15 in gastric cancer.
Neoplasm Metastasis
The diagnostic and prognostic value of serum human kallikrein-related peptidases 11 in non-small cell lung cancer.
Neoplasm, Residual
Clinical relevance of kallikrein-related peptidase 9, 10, 11, and 15 mRNA expression in advanced high-grade serous ovarian cancer.
Neoplasms
Association of TMPRSS2 and KLK11 gene expression levels with clinical progression of human prostate cancer.
Neoplasms
Cancer-associated fibroblast stimulates cancer cell invasion in an interleukin-1 receptor (IL-1R)-dependent manner.
Neoplasms
Development of a survival prediction model for gastric cancer using serine proteases and their inhibitors.
Neoplasms
Diagnostic and prognostic significance of human kallikrein 11 (KLK11) mRNA expression levels in patients with laryngeal cancer.
Neoplasms
Elevated tumor tissue protein expression levels of kallikrein-related peptidases KLK10 and KLK11 are associated with a better prognosis in advanced high-grade serous ovarian cancer patients.
Neoplasms
Expression analysis and prognostic significance of human kallikrein 11 in prostate cancer.
Neoplasms
Human kallikrein gene 11 (KLK11) mRNA overexpression is associated with poor prognosis in patients with epithelial ovarian cancer.
Neoplasms
Identification and validation of Kallikrein-ralated peptidase 11 as a novel prognostic marker of gastric cancer based on immunohistochemistry.
Neoplasms
Immunohistochemical localization and analysis of kallikrein-related peptidase 7 and 11 expression in paired cancer and benign foci in prostate cancer patients.
Neoplasms
Kallikrein 11 expressed in human breast cancer cells releases insulin-like growth factor through degradation of IGFBP-3.
Neoplasms
Kallikrein-11, in Association with Coiled-Coil Domain Containing 25, as a Potential Prognostic Marker for Cholangiocarcinoma with Lymph Node Metastasis.
Neoplasms
KLK11 acts as a tumor-inhibitor in laryngeal squamous cell carcinoma through the inactivation of Akt/Wnt/?-catenin signaling.
Neoplasms
KLK11 mRNA expression predicts poor disease-free and overall survival in colorectal adenocarcinoma patients.
Neoplasms
Knockdown of KLK11 inhibits cell proliferation and increases oxaliplatin sensitivity in human colorectal cancer.
Neoplasms
Novel Biomarkers Aim at Detecting Metastatic Sentinel Lymph Nodes in Breast Cancer
Neoplasms
Novel splice variants of the human kallikrein-related peptidases 11 (KLK11) and 12 (KLK12), unraveled by next-generation sequencing technology.
Neoplasms
Prognostic significance of human tissue kallikrein-related peptidases 11 and 15 in gastric cancer.
Neoplasms
Quantitative analysis of hippostasin/KLK11 gene expression in cancerous and noncancerous prostatic tissues.
Neuroblastoma
Immunoreactivity, ultrastructural localization, and transcript expression of prostate-specific antigen in human neuroblastoma cell lines.
Ovarian Neoplasms
Clinical relevance of kallikrein-related peptidase 9, 10, 11, and 15 mRNA expression in advanced high-grade serous ovarian cancer.
Ovarian Neoplasms
Elevated tumor tissue protein expression levels of kallikrein-related peptidases KLK10 and KLK11 are associated with a better prognosis in advanced high-grade serous ovarian cancer patients.
Ovarian Neoplasms
Human kallikrein 11: an indicator of favorable prognosis in ovarian cancer patients.
Ovarian Neoplasms
Human kallikrein gene 11 (KLK11) mRNA overexpression is associated with poor prognosis in patients with epithelial ovarian cancer.
Ovarian Neoplasms
Purification and characterization of human kallikrein 11, a candidate prostate and ovarian cancer biomarker, from seminal plasma.
Ovarian Neoplasms
Validation and characterization of human kallikrein 11 as a serum marker for diagnosis of ovarian carcinoma.
Pancreatic Neoplasms
Kallikrein-Related Peptidase 6 Is Associated with the Tumour Microenvironment of Pancreatic Ductal Adenocarcinoma.
Prostatic Hyperplasia
mRNA expression analysis of human kallikrein 11 (KLK11) may be useful in the discrimination of benign prostatic hyperplasia from prostate cancer after needle prostate biopsy.
Prostatic Hyperplasia
The usefulness of serum human kallikrein 11 for discriminating between prostate cancer and benign prostatic hyperplasia.
Prostatic Neoplasms
Alternative splicing isoforms of hippostasin (PRSS20/KLK11) in prostate cancer cell lines.
Prostatic Neoplasms
Association of TMPRSS2 and KLK11 gene expression levels with clinical progression of human prostate cancer.
Prostatic Neoplasms
Expression analysis and prognostic significance of human kallikrein 11 in prostate cancer.
Prostatic Neoplasms
Immunohistochemical localization and analysis of kallikrein-related peptidase 7 and 11 expression in paired cancer and benign foci in prostate cancer patients.
Prostatic Neoplasms
Improved prostate cancer detection with a human kallikrein 11 and percentage free PSA-based artificial neural network.
Prostatic Neoplasms
Is there a role for serum human tissue kallikrein in detection of prostate cancer?
Prostatic Neoplasms
Molecular cloning and expression of a variant form of hippostasin/KLK11 in prostate.
Prostatic Neoplasms
mRNA expression analysis of human kallikrein 11 (KLK11) may be useful in the discrimination of benign prostatic hyperplasia from prostate cancer after needle prostate biopsy.
Prostatic Neoplasms
Quantitative analysis of hippostasin/KLK11 gene expression in cancerous and noncancerous prostatic tissues.
Prostatic Neoplasms
The usefulness of serum human kallikrein 11 for discriminating between prostate cancer and benign prostatic hyperplasia.
Prostatic Neoplasms
Treatment of PC3 prostate cancer cells with mitoxantrone, etoposide, doxorubicin and carboplatin induces distinct alterations in the expression of kallikreins 5 and 11.
Psoriasis
Aberrant human tissue kallikrein levels in the stratum corneum and serum of patients with psoriasis: dependence on phenotype, severity and therapy.
Seizures
Nerve agent poisoning in primates: antilethal, anti-epileptic and neuroprotective effects of GK-11.
Squamous Cell Carcinoma of Head and Neck
KLK11 acts as a tumor-inhibitor in laryngeal squamous cell carcinoma through the inactivation of Akt/Wnt/?-catenin signaling.
Stomach Neoplasms
Identification and validation of Kallikrein-ralated peptidase 11 as a novel prognostic marker of gastric cancer based on immunohistochemistry.
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