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Disease on EC 3.4.21.83 - Oligopeptidase B

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Aggressive Periodontitis
Salivary collagenase, elastase- and trypsin-like proteases as biochemical markers of periodontal tissue destruction in adult and localized juvenile periodontitis.
Amnesia
The prolyl oligopeptidase family.
Blister
Proteases are responsible for blister formation in recessive dystrophic epidermolysis bullosa and epidermolysis bullosa simplex.
Breast Neoplasms
Isolation of a protease from the cell-free medium of in vitro cultured mammary carcinoma.
Carcinoma
Isolation of a protease from the cell-free medium of in vitro cultured mammary carcinoma.
Prostatic human kallikrein 2 inactivates and complexes with plasminogen activator inhibitor-1.
Chagas Disease
Specific human antibodies do not inhibit Trypanosoma cruzi oligopeptidase B and cathepsin B, and immunoglobulin G enhances the activity of trypomastigote-secreted oligopeptidase B.
The Trypanosoma cruzi virulence factor oligopeptidase B (OPBTc) assembles into an active and stable dimer.
Chronic Periodontitis
Analysis of cultivable Porphyromonas gingivalis with trypsin-like protease enzyme activity and serum antibodies in chronic adult periodontitis.
Inhibition of polymorphonuclear leucocyte phagocytosis by Porphyromonas gingivalis culture products in patients with adult periodontitis.
Salivary collagenase, elastase- and trypsin-like proteases as biochemical markers of periodontal tissue destruction in adult and localized juvenile periodontitis.
Communicable Diseases
Substrate recognition properties of oligopeptidase B from Salmonella enterica serovar Typhimurium.
Cystic Fibrosis
Sputum trypsin-like protease activity relates to clinical outcome in cystic fibrosis.
Cysts
Detection of trypsin- and chymotrypsin-like proteases using p-nitroanilide substrates after sodium dodecyl sulphate polyacrylamide gel electrophoresis.
Human ovarian tumor-associated trypsin. Its purification and characterization from mucinous cyst fluid and identification as an activator of pro-urokinase.
Dental Plaque
Characterization of a trypsin-like protease from the bacterium Bacteroides gingivalis isolated from human dental plaque.
Quantification of the bacterium Bacteroides gingivalis in human dental plaque by detection of the trypsin-like protease activity of colonies imprinted on membrane filters.
Diabetes Mellitus, Type 2
The prolyl oligopeptidase family.
Hepatitis C
The RNA aptamer-binding site of hepatitis C virus NS3 protease.
Herpes Zoster
Immunodetection of acrosin during the acrosome reaction of hamster, guinea-pig and human spermatozoa.
Intactness of zona pellucida does not affect the secretion of a trypsin-like protease from mouse blastocyst.
The zona reaction of hamster and mouse eggs: production in vitro by a trypsin-like protease from cortical granules.
Hypersensitivity
A Novel Serine Protease Inhibitor PE-BBI Ameliorates Cockroach Extract-Mediated Airway Epithelial Barrier Dysfunction.
Thrombin generates monocyte chemotactic activity from complement factor H.
Hypersensitivity, Delayed
The chemical mediation of delayed hypersensitivity skin reactions. IV. Activation of chemotactic factor precursor by a trypsin-like protease in guinea pig plasma.
Infections
A new Sendai virus vector deficient in the matrix gene does not form virus particles and shows extensive cell-to-cell spreading.
Oligopeptidase B-dependent signaling mediates host cell invasion by Trypanosoma cruzi.
Transcriptome of an entomophthoralean fungus (Pandora formicae) shows molecular machinery adjusted for successful host exploitation and transmission.
Virulence of a polymicrobic complex, Treponema denticola and Porphyromonas gingivalis, in a murine model.
Influenza, Human
Electron immunohistochemical localization in rat bronchiolar epithelial cells of tryptase Clara, which determines the pneumotropism and pathogenicity of Sendai virus and influenza virus.
Growth activation of influenza virus by trypsin and effect of T-705 (favipiravir) on trypsin-optimized growth condition.
Human mucus protease inhibitor in airway fluids is a potential defensive compound against infection with influenza A and Sendai viruses.
Professional oral health care by dental hygienists reduced respiratory infections in elderly persons requiring nursing care.
The human mucus protease inhibitor and its mutants are novel defensive compounds against infection with influenza A and Sendai viruses.
[Proteolysis intensification during influenza virus interaction with plasma membrane of sensitive cells]
Leiomyoma
Protease activity in fibromyoma and normal human myometrium.
Leishmaniasis
Mechanistic insights into mode of actions of novel oligopeptidase B inhibitors for combating leishmaniasis.
Leishmaniasis, Mucocutaneous
Specific human antibodies do not inhibit Trypanosoma cruzi oligopeptidase B and cathepsin B, and immunoglobulin G enhances the activity of trypomastigote-secreted oligopeptidase B.
Leishmaniasis, Visceral
Evaluation of CAAX prenyl protease II of Leishmania donovani as potential drug target: Infectivity and growth of the parasite is significantly lowered after the gene knockout.
Specific human antibodies do not inhibit Trypanosoma cruzi oligopeptidase B and cathepsin B, and immunoglobulin G enhances the activity of trypomastigote-secreted oligopeptidase B.
Muscular Dystrophies
Expression of trypsin-like proteases and protease nexin-1 in mdx mouse muscles.
Preclinical increase in activity of muscle microsomal trypsin-like protease in murine muscular dystrophy, C57BL/10-mdx.
Muscular Dystrophy, Duchenne
Therapeutic effect of camostat mesilate on Duchenne muscular dystrophy in mdx mice.
Neoplasm Metastasis
Human kallikrein 2 (hK2), but not prostate-specific antigen (PSA), rapidly complexes with protease inhibitor 6 (PI-6) released from prostate carcinoma cells.
Surface-enhanced Raman and steady fluorescence study of interaction between antitumoral drug 9-aminoacridine and trypsin-like protease related to metastasis processes, guanidinobenzoatase.
Neoplasms
A study of guanidinobenzoatase during development of mesothelioma induced in the rat by fibrous erionite.
Detection of trypsin- and chymotrypsin-like proteases using p-nitroanilide substrates after sodium dodecyl sulphate polyacrylamide gel electrophoresis.
Human kallikrein 2 (hK2), but not prostate-specific antigen (PSA), rapidly complexes with protease inhibitor 6 (PI-6) released from prostate carcinoma cells.
Human ovarian tumor-associated trypsin. Its purification and characterization from mucinous cyst fluid and identification as an activator of pro-urokinase.
Interaction of the antitumor drug 9-aminoacridine with guanidinobenzoatase studied by spectroscopic methods: a possible tumor marker probe based on the fluorescence exciplex emission.
Plasmin: Its Role in the Extracellular Processing of Progalanin in Tumor Tissue.
Surface-enhanced Raman and steady fluorescence study of interaction between antitumoral drug 9-aminoacridine and trypsin-like protease related to metastasis processes, guanidinobenzoatase.
Periodontal Diseases
Analysis of cultivable Porphyromonas gingivalis with trypsin-like protease enzyme activity and serum antibodies in chronic adult periodontitis.
Periodontitis
Serum-antibodies against the trypsin-like protease of Bacteroides gingivalis in periodontitis.
Prostatic Neoplasms
Human kallikrein 2 (hK2), but not prostate-specific antigen (PSA), rapidly complexes with protease inhibitor 6 (PI-6) released from prostate carcinoma cells.
Scrapie
Recombinant alkaline serine protease II degrades scrapie isoform of prion protein.
Trypanosomiasis
The prolyl oligopeptidase family.
The Trypanosoma cruzi virulence factor oligopeptidase B (OPBTc) assembles into an active and stable dimer.
Trypanosomiasis, African
A Critical Role for highly Conserved GLU610 Residue of Oligopeptidase B from Trypanosoma Brucei in Thermal Stability.
Crystal structures of Trypanosoma brucei oligopeptidase B broaden the paradigm of catalytic regulation in prolyl oligopeptidase family enzymes.
Identification of the reactive cysteine residues in oligopeptidase B from Trypanosoma brucei.
Trypanosome-derived oligopeptidase B is released into the plasma of infected rodents, where it persists and retains full catalytic activity.