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Ac-Asp-Glu-Val-Asp-4-methylcoumaryl-7-amide + H2O
Ac-Asp-Glu-Val-Asp + 7-amino-4-methylcoumarin
Substrates: -
Products: release of 0.4 nM product per min
?
Boc-Arg-Val-Arg-Arg-4-methylcoumaryl-7-amide + H2O
Boc-Arg-Val-Arg-Arg + 7-amino-4-methylcoumarin
Substrates: -
Products: -
?
Boc-Asp(OBzl)-Pro-Arg-4-methylcoumaryl-7-amide + H2O
Boc-Asp(OBzl)-Pro-Arg + 7-amino-4-methylcoumarin
Substrates: -
Products: release of 2.0 nM product per min
?
Boc-Glu(OBzl)-Ala-Arg-4-methylcoumaryl-7-amide + H2O
Boc-Glu(OBzl)-Ala-Arg + 7-amino-4-methylcoumarin
Substrates: -
Products: release of 1.8 nM product per min
?
Boc-Glu-Lys-Lys-4-methylcoumaryl-7-amide + H2O
Boc-Glu-Lys-Lys + 7-amino-4-methylcoumarin
Boc-Gly-Arg-Arg-4-methylcoumaryl-7-amide + H2O
Boc-Gly-Arg-Arg + 7-amino-4-methylcoumarin
Substrates: -
Products: release of 1.0 nM product per min
?
Boc-Gly-Lys-Arg-4-methylcoumaryl-7-amide + H2O
Boc-Gly-Lys-Arg + 7-amino-4-methylcoumarin
Substrates: -
Products: -
?
Boc-Ile-Glu-Gly-Arg-4-methylcoumaryl-7-amide + H2O
Boc-Ile-Glu-Gly-Arg + 7-amino-4-methylcoumarin
Substrates: -
Products: release of 64 nM product per min
?
Boc-Leu-Lys-Arg-4-methylcoumaryl-7-amide + H2O
Boc-Leu-Lys-Arg + 7-amino-4-methylcoumarin
Substrates: -
Products: release of 7.0 nM product per min
?
Boc-Leu-Ser-Thr-Arg-4-methylcoumaryl-7-amide + H2O
Boc-Leu-Ser-Thr-Arg + 7-amino-4-methylcoumarin
Substrates: -
Products: release of 45 nM product per min
?
Boc-Leu-Thr-Arg-4-methylcoumaryl-7-amide + H2O
Boc-Leu-Thr-Arg + 7-amino-4-methylcoumarin
Substrates: -
Products: release of 1.5 nM product per min
?
Boc-Phe-Ser-Arg-4-methylcoumaryl-7-amide + H2O
Boc-Phe-Ser-Arg + 7-amino-4-methylcoumarin
Substrates: -
Products: release of 2.2 nM product per min
?
Boc-Val-Leu-Lys-4-methylcoumaryl-7-amide + H2O
Boc-Val-Leu-Lys + 7-amino-4-methylcoumarin
Substrates: -
Products: release of 1.3 nM product per min
?
complement component C5 + H2O
complement component C5a + ?
Substrates: -
Products: -
?
Fibrinogen + H2O
?
Substrates: -
Products: -
?
Gly-Pro-4-methylcoumaryl-7-amide + H2O
Gly-Pro + 7-amino-4-methylcoumarin
Substrates: -
Products: release of 0.4 nM product per min
?
prekallikrein + H2O
?
Substrates: -
Products: -
?
prothrombin + H2O
alpha-thrombin + prothrombin fragments
Substrates: -
Products: -
?
Pyr-Arg-Thr-Lys-Arg-4-methylcoumaryl-7-amide + H2O
Pyr-Arg-Thr-Lys-Arg + 7-amino-4-methylcoumarin
Suc(OMe)-Ala-Ala-Pro-Val-4-methylcoumaryl-7-amide + H2O
Suc(OMe)-Ala-Ala-Pro-Val + 7-amino-4-methylcoumarin
Substrates: -
Products: release of 1.2 nM product per min
?
Suc-Ala-Ala-Pro-Phe-4-methylcoumaryl-7-amide + H2O
Suc-Ala-Ala-Pro-Phe + 7-amino-4-methylcoumarin
Substrates: -
Products: release of 1.8 nM product per min
?
Boc-Glu-Lys-Lys-4-methylcoumaryl-7-amide + H2O
Boc-Glu-Lys-Lys + 7-amino-4-methylcoumarin
Substrates: -
Products: -
?
Boc-Glu-Lys-Lys-4-methylcoumaryl-7-amide + H2O
Boc-Glu-Lys-Lys + 7-amino-4-methylcoumarin
Substrates: best artificial substrate
Products: release of 82 nM product per min
?
Pyr-Arg-Thr-Lys-Arg-4-methylcoumaryl-7-amide + H2O
Pyr-Arg-Thr-Lys-Arg + 7-amino-4-methylcoumarin
Substrates: -
Products: -
?
Pyr-Arg-Thr-Lys-Arg-4-methylcoumaryl-7-amide + H2O
Pyr-Arg-Thr-Lys-Arg + 7-amino-4-methylcoumarin
Substrates: -
Products: release of 45 nM product per min
?
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Kobayashi, H.; Takahashi, E.; Oguma, K.; Fujii, Y.; Yamanaka, H.; Negishi, T.; Arimoto-Kobayashi, S.; Tsuji, T.; Okamoto, K.
Cleavage specificity of the serine protease of Aeromonas sobria, a member of the kexin family of subtilases
FEMS Microbiol. Lett.
256
165-170
2006
Aeromonas sobria (Q9L5A4)
brenda
Murakami, Y.; Wada, Y.; Kobayashi, H.; Irie, A.; Hasegawa, M.; Yamanaka, H.; Okamoto, K.; Eto, M.; Imamura, T.
Inhibition of Aeromonas sobria serine protease (ASP) by alpha -macroglobulin
Biol. Chem.
393
1193-1200
2012
Aeromonas sobria (Q9L5A4)
brenda
Nitta, H.; Kobayashi, H.; Irie, A.; Baba, H.; Okamoto, K.; Imamura, T.
Activation of prothrombin by ASP, a serine protease released from Aeromonas sobria
FEBS Lett.
581
5935-5939
2007
Aeromonas sobria (Q9L5A4)
brenda
Imamura, T.; Nitta, H.; Wada, Y.; Kobayashi, H.; Okamoto, K.
Impaired plasma clottability induction through fibrinogen degradation byASP, a serine protease released fromAeromonas sobria
FEMS MIcrobiol. Lett.
284
1574-6968
2008
Aeromonas sobria (Q9L5A4)
brenda
Kobayashi, H.; Utsunomiya, H.; Yamanaka, H.; Sei, Y. Katunuma, N.; Okamoto, K.; Tsuge, H.
Structural basis for the kexin-like serine protease from Aeromonas sobria as sepsis-causing factor
J. Biol. Chem.
284
27655-27663
2009
Aeromonas sobria (Q9L5A4)
brenda
Nitta, H.; Imamura, T.; Wada, Y.; Irie, A.; Kobayashi, H.; Okamoto, K.; Baba, H.
Production of C5a by ASP, a serine protease released from Aeromonas sobria
J. Immunol.
181
3602-3608
2008
Aeromonas sobria (Q9L5A4)
brenda
Okamoto, K.; Nomura, T.; Hamada, M.; Fukuda, T.; Noguchi, Y.; Fujii, Y.
Production of serine protease of Aeromonas sobria is controlled by the protein encoded by the gene lying adjacent to the 3' end of the protease gene
Microbiol. Immunol.
44
787-798
2000
Aeromonas sobria (Q9L5A4)
brenda