BRENDA - Enzyme Database show
show all sequences of 3.4.21.121

Cleavage specificity of the serine protease of Aeromonas sobria, a member of the kexin family of subtilases

Kobayashi, H.; Takahashi, E.; Oguma, K.; Fujii, Y.; Yamanaka, H.; Negishi, T.; Arimoto-Kobayashi, S.; Tsuji, T.; Okamoto, K.; FEMS Microbiol. Lett. 256, 165-170 (2006)

Data extracted from this reference:

Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
extracellular
-
Aeromonas sobria
-
-
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
65000
-
SDS-PAGE
Aeromonas sobria
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Aeromonas sobria
Q9L5A4
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Boc-Arg-Val-Arg-Arg-4-methylcoumaryl-7-amide + H2O
-
686780
Aeromonas sobria
Boc-Arg-Val-Arg-Arg + 7-amino-4-methylcoumarin
-
-
-
?
Boc-Glu-Lys-Lys-4-methylcoumaryl-7-amide + H2O
-
686780
Aeromonas sobria
Boc-Glu-Lys-Lys + 7-amino-4-methylcoumarin
-
-
-
?
Boc-Gly-Lys-Arg-4-methylcoumaryl-7-amide + H2O
-
686780
Aeromonas sobria
Boc-Gly-Lys-Arg + 7-amino-4-methylcoumarin
-
-
-
?
Pyr-Arg-Thr-Lys-Arg-4-methylcoumaryl-7-amide + H2O
-
686780
Aeromonas sobria
Pyr-Arg-Thr-Lys-Arg + 7-amino-4-methylcoumarin
-
-
-
?
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
extracellular
-
Aeromonas sobria
-
-
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
65000
-
SDS-PAGE
Aeromonas sobria
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Boc-Arg-Val-Arg-Arg-4-methylcoumaryl-7-amide + H2O
-
686780
Aeromonas sobria
Boc-Arg-Val-Arg-Arg + 7-amino-4-methylcoumarin
-
-
-
?
Boc-Glu-Lys-Lys-4-methylcoumaryl-7-amide + H2O
-
686780
Aeromonas sobria
Boc-Glu-Lys-Lys + 7-amino-4-methylcoumarin
-
-
-
?
Boc-Gly-Lys-Arg-4-methylcoumaryl-7-amide + H2O
-
686780
Aeromonas sobria
Boc-Gly-Lys-Arg + 7-amino-4-methylcoumarin
-
-
-
?
Pyr-Arg-Thr-Lys-Arg-4-methylcoumaryl-7-amide + H2O
-
686780
Aeromonas sobria
Pyr-Arg-Thr-Lys-Arg + 7-amino-4-methylcoumarin
-
-
-
?
Other publictions for EC 3.4.21.121
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
719026
Murakami
Inhibition of Aeromonas sobria ...
Aeromonas sobria
Biol. Chem.
393
1193-1200
2012
-
-
-
-
-
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1
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1
-
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1
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1
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1
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1
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1
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719852
Kobayashi
Structural basis for the kexin ...
Aeromonas sobria
J. Biol. Chem.
284
27655-27663
2009
-
-
-
1
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1
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1
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1
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1
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2
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1
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1
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1
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1
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2
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719520
Imamura
Impaired plasma clottability i ...
Aeromonas sobria
FEMS MIcrobiol. Lett.
284
1574-6968
2008
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-
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1
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1
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1
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2
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1
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1
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2
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720155
Nitta
Production of C5a by ASP, a se ...
Aeromonas sobria
J. Immunol.
181
3602-3608
2008
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-
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1
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1
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1
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1
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1
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719490
Nitta
Activation of prothrombin by A ...
Aeromonas sobria
FEBS Lett.
581
5935-5939
2007
-
-
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-
-
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1
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1
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1
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16
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1
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1
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16
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686780
Kobayashi
Cleavage specificity of the se ...
Aeromonas sobria
FEMS Microbiol. Lett.
256
165-170
2006
-
-
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-
-
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1
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1
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1
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4
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1
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1
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4
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720380
Okamoto
Production of serine protease ...
Aeromonas sobria
Microbiol. Immunol.
44
787-798
2000
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1
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1
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1
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1
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1
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1
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