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Information on EC 3.4.21.1 - chymotrypsin
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Word Map
- 3.4.21.1
- pancreatic
- elastase
- proteinase
- pepsin
- pancreas
- subtilisin
- lipase
- amylase
- thrombin
-
exocrine
- cathepsin
- porcine
- soybean
- pronase
- aureus
-
chymotryptic
- plasmin
- staphylococcus
- erythrocyte
- kallikrein
- carboxypeptidase
- thermolysin
- bromide
-
trypsin-like
- juice
-
bowman-birk
- duodenal
-
cyanogen
-
edman
-
kunitz-type
- collagenase
-
kunitz
- midguts
- zymogen
- neuraminidase
- serpins
- cholecystokinin
- trypsinogen
- secretin
-
2-macroglobulin
- chymase
- bromelain
- aprotinin
-
chloromethyl
- p-nitroanilide
- medicine
- synthesis
- gizzard
- biotechnology
- meromyosin
-
non-cholinergic
-
amidolytic
- drug development
- acyl-enzyme
- agriculture
- industry
The enzyme appears in viruses and cellular organisms
Synonyms
chymotrypsin, alpha-chymotrypsin, bovine alpha-chymotrypsin, chymotrypsin a, alpha-ct, chymotrypsin b, chtp, alpha chymotrypsin, alpha-chymotrypsin a, chymotrypsin ii, 
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
alpha chymar
-
-
-
-
alpha-chymar ophth
-
-
-
-
alpha-chymotrypsin
-
-
-
-
alpha-chymotrypsin A
-
-
-
-
avazyme
-
-
-
-
chymar
-
-
-
-
chymotest
-
-
-
-
chymotrypsin A
-
-
-
-
chymotrypsin B
-
-
-
-
EC 3.4.4.6
-
-
-
-
enzeon
-
-
-
-
quimar
-
-
-
-
quimotrase
-
-
-
-
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CAS REGISTRY NUMBER
COMMENTARY
9004-07-3
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
N-benzoyl-L-Tyr-p-nitroanilide + H2O
N-benzoyl-L-tyrosine + 4-nitroaniline
-
-
-
?
N-succinyl-Ala-Ala-Phe-7-amido-4-methylcoumarin + H2O
N-succinyl-Ala-Ala-Phe + 7-amino-4-methylcoumarin
-
-
-
?
N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide + H2O
N-succinyl-Ala-Ala-Pro-Phe + 4-nitroaniline
-
-
-
?
N-succinyl-Leu-Tyr-7-amido-4-methylcoumarin + H2O
N-succinyl-Leu-Tyr + 7-amino-4-methylcoumarin
-
-
-
?
N-succinyl-Phe-7-amido-4-methylcoumarin + H2O
N-succinyl-Phe + 7-amino-4-methylcoumarin
-
-
-
?
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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acquired Immunodeficiency Syndrome
Trypsin and chymotrypsin as aids in the diagnosis of pancreatic disease.
Adenocarcinoma
Immunohistochemical characterization of pancreatic tumors induced by dimethylbenzanthracene in rats.
Adenocarcinoma
Production and characterization of monoclonal antibody to a 60-kD glycoprotein in ovarian carcinoma.
Adenocarcinoma
Serine protease modulation of Dependence Receptors and EMT protein expression.
Adenocarcinoma
The prevalence of pancreatic acinar differentiation in gastric adenocarcinoma: report of a case and immunohistochemical study of 111 additional cases.
Adenocarcinoma
[Combined action of alpha-chymotrypsin and testicular hyaluronidase on the take of the homotransplant of a spontaneous mammary adenocarcinoma in Swiss mice]
African Horse Sickness
The effect of temperature on the in vitro transcriptase reaction of bluetongue virus, epizootic haemorrhagic disease virus and African horsesickness virus.
Alzheimer Disease
Cerebrospinal fluid of patients with senile dementia of Alzheimer's type shows an increased inhibition of alpha-chymotrypsin.
Alzheimer Disease
Structural features of the Abeta amyloid fibril elucidated by limited proteolysis.
Alzheimer Disease
Synthesis of new 3-alkoxy-7-amino-4-chloro-isocoumarin derivatives as new beta-amyloid peptide production inhibitors and their activities on various classes of protease.
Anaphylaxis
ANAPHYLACTIC REACTION CAUSED BY INTRAMUSCULAR INJECTION OF LYOPHILIZED ALPHA-CHYMOTRYPSIN.
Anemia, Dyserythropoietic, Congenital
Red cell membrane protein anomalies in congenital dyserythropoietic anaemia, type II (HEMP AS).
Aphakia
[4-YEAR FOLLOW-UP OF APHAKIC EYES SURGICALLY TREATED WITH THE USE OF ALPHA-CHYMOTRYPSIN.]
Aphakia
[Retinal detachment in aphakic eye following cataract extraction with use of chymotrypsin]
Arteriosclerosis
[Intra-arterial infusion of alpha-chymotrypsin in the treatment of vascular infarcts during the course of arteriosclerosis.]
Arteriosclerosis Obliterans
[Intraarterial treatment with alpha-chymotrypsin in arteriosclerosis obliterans.]
Avitaminosis
Shwachman-diamond syndrome: a complex case demonstrating the potential for misdiagnosis as asphyxiating thoracic dystrophy (jeune syndrome).
Bacterial Infections
Bacterial infection microenvironment-responsive enzymatically degradable multilayer films for multifunctional antibacterial properties.
Bacterial Infections
Experimental and clinical studies on the serum level of alpha-chymotrypsin inhibitors in bacterial infection.
Bernard-Soulier Syndrome
Contrasting effects of thrombin and the thrombin receptor peptide, SFLLRN, on aggregation and release of 14C-serotonin by human platelets pretreated with chymotrypsin or serratia marcescens protease.
Bernard-Soulier Syndrome
pH and magnesium alter 45calcium binding to platelets at sites other than glycoproteins I or IIb/IIIa.
Bernard-Soulier Syndrome
The agglutination of human platelets by botrocetin: evidence that botrocetin and ristocetin act at different sites on the factor VIII molecule and platelet membrane.
Blister
Decreased specific anti-elastase activity in the uninvolved skin of patients with psoriasis.
Blister
Elevated serum chymotrypsin levels in a patient with junctional epidermolysis bullosa. Normalization after UVB therapy with good clinical response.
Bluetongue
Effects of proteolytic enzymes on the infectivity, haemagglutinating activity and protein composition of bluetongue virus type 20.
Bluetongue
Purification and properties of virus particles, infectious subviral particles, cores and VP7 crystals of African horsesickness virus serotype 9.
Bluetongue
The effect of temperature on the in vitro transcriptase reaction of bluetongue virus, epizootic haemorrhagic disease virus and African horsesickness virus.
Breast Neoplasms
Farnesyl and geranylgeranyl transferase inhibitors induce G1 arrest by targeting the proteasome.
Bronchial Diseases
[Significance of enzyme therapy with oral trypsin and chymotrypsin in chronic bronchial diseases in the course of inhalatory balneotherapy and of pulmonary ventilation]
Bronchitis, Chronic
Chronic bronchitis. Controlled trial of isoprenaline and chymotrypsin by inhalation.
Carcinogenesis
Bowman-Birk inhibitor abates proteasome function and suppresses the proliferation of MCF7 breast cancer cells through accumulation of MAP kinase phosphatase-1.
Carcinogenesis
Effects of various preparations of dietary protease inhibitors on oral carcinogenesis in hamsters induced by DMBA.
Carcinogenesis
Protease inhibitor suppression of colon and anal gland carcinogenesis induced by dimethylhydrazine.
Carcinogenesis
Suppression of 3-methylcholanthrene-induced cellular transformation by timed administration of the Bowman-Birk protease inhibitor.
Carcinoma
Acinar cell carcinoma of the pancreas metastatic to the ovary: a report of 4 cases.
Carcinoma
Ductal origin of pancreatic adenocarcinomas induced by conditional activation of a human Ha-ras oncogene in rat pancreas.
Carcinoma
Papillary cystic tumor of the pancreas. An analysis of cellular differentiation by electron microscopy and immunohistochemistry.
Carcinoma
Serine protease inhibitor activity of recombinant squamous cell carcinoma antigen towards chymotrypsin, as demonstrated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.
Carcinoma
[Successful Surgical Resection of Expansive-Growth Acinar Cell Carcinoma-A Case Report].
Carcinoma
[The effect of fructose on chymotrypsin inhibitor and on the protein fractions in the serum of carcinoma patients.]
Carcinoma, Acinar Cell
Acinar cell carcinoma of the pancreas metastatic to the ovary: a report of 4 cases.
Carcinoma, Acinar Cell
[Successful Surgical Resection of Expansive-Growth Acinar Cell Carcinoma-A Case Report].
Carcinoma, Hepatocellular
Expression and characterization of a novel human recombinant factor IX molecule with enhanced in vitro and in vivo clotting activity.
Carcinoma, Non-Small-Cell Lung
Identification and Target-Modification of SL-BBI: A Novel Bowman-Birk Type Trypsin Inhibitor from Sylvirana latouchii.
Carcinoma, Squamous Cell
Serine protease inhibitor activity of recombinant squamous cell carcinoma antigen towards chymotrypsin, as demonstrated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.
Cataract
A double-blind therapeutic trial of the effect of alpha-chymotrypsin on the facility of cataract extraction.
Cataract
A fluorophotometric study of the barrier functions in the anterior segment of the eye after intracapsular cataract extraction.
Cataract
Alpha-chymotrypsin in cataract surgery. A report on English eight cases.
Cataract
Alpha-chymotrypsin in cataract surgery: a preliminary report of experiences with one hundred thirtytwo cases.
Cataract
Alpha-chymotrypsin in cataract surgery: an operative and postoperative study in 80 cataract extractions.
Cataract
Alpha-chymotrypsin in cataract surgery: indications, contraindications, and complications.
Cataract
Comparison of 50 cataract operations with and 50 without the aid of alpha-chymotrypsin.
Cataract
Dose relationship of alpha chymotrypsin in production of glaucoma after cataract extraction.
Cataract
Further studies on glaucoma following cataract extraction associated with the use of alpha-chymotrypsin.
Cataract
Raised intraocular tension following the use of alpha-chymotrypsin in cataract surgery.
Cataract
The effect of timolol and acetazolamide on transient intraocular pressure elevation following cataract extraction with alpha-chymotrypsin.
Cataract
TONOGRAPHY AND GONIOSCOPY; BEFORE AND AFTER CATARACT EXTRACTION WITH ALPHA CHYMOTRYPSIN.
Cataract
[Comparison of pre- and postoperative endothelial cell count following intracapsulary cataract surgery with and without administration of alpha chymotrypsin]
Cataract
[Comparison of the results of cataract operations done with and without alpha-chymotrypsin.]
Cataract
[Complications caused by a pancreatic inhibitor of alpha-chymotrypsin in cataract extraction.]
Cataract
[Considerations on the study of 225 cataracts operated on with the use of alpha-chymotrypsin]
Cataract
[Contribution to the study of the complications of cataract extraction with alpha-chymotrypsin]
Cataract
[Enzymatic zonulolysis; personal experience on the use of alpha-chymotrypsin in cataract surgery.]
Cataract
[EXPERIENCE WITH ALPHA-CHYMOTRYPSIN IN CATARACT SURGERY AND RESULTS WITH 125 CASES OF SIMULTANEOUS OPERATION ON BOTH EYES.]
Cataract
[Further observations on the use of alpha-chymotrypsin in cataract operations.]
Cataract
[Immediate detachment of the choroid and alpha-chymotrypsin in cataract extraction.]
Cataract
[Intracapsular cataract extraction by the pressure method with alpha-chymotrypsin.]
Cataract
[Metipranolol in the prevention of intraocular pressure elevation after cataract extraction]
Cataract
[ON RETRO-CORNEAL PIGMENTATION FOLLOWING TOTAL CATARACT EXTRACTION USING ALPHA-CHYMOTRYPSIN.]
Cataract
[Pathological-anatomical data on 2 eyes operated on for cataract with alpha-chymotrypsin.]
Cataract
[Retinal detachment in aphakic eye following cataract extraction with use of chymotrypsin]
Cataract
[Studies on the effect of the pancreatic enzymes alpha-chymotrypsin and trypsin on the lens capsule in cataract extraction with enzymatic zonulysis.]
Catheter-Related Infections
Prevention of catheter-related infections by a new, catheter-restricted antibiotic filling technique.
Catheter-Related Infections
Simultaneous measurement of metabolic flux in portally-drained viscera, liver, spleen, kidney and hindquarter in the conscious pig.
Celiac Disease
Comparative study of the estimation of exocrine pancreatic function using p-(N-acetyl-L-tyrosyl)- and p-(N-benzoyl-L-tyrosyl)aminobenzoic acid.
Celiac Disease
Role of pancreatic impairment in growth recovery during gluten-free diet in childhood celiac disease.
Cholestasis
Effect of bile duct obstruction on pancreatic enzyme secretion and intestinal proteolytic enzyme activity in the rat.
Chondrosarcoma
An amino acid sequence common to both cartilage proteoglycan and link protein.
Chondrosarcoma
Purification and characterization of a hyaluronan-binding protein from rat chondrosarcoma.
Choroid Diseases
[Various retinal & choroid diseases successfully treated with retrobulbar hydrocortisone and/or alpha-chymotrypsin.]
chymotrypsin deficiency
Cytochemical determination of granulocyte elastase and chymotrypsin in human myeloid cells and its application in acquired deficiency states and diagnosis of myeloid leukemia.
chymotrypsin deficiency
Pancreatic dysfunction and its association with fat malabsorption in HIV infected children.
Classical Swine Fever
[Studies on the increase of weights of lymphatic glands, of lymph and peritoneal fluid and their contents of chymotrypsin and virus in pigs suffering hog cholera (author's transl)]
coagulation factor viia deficiency
Molecular mechanism of dysfunctional factor VII associated with the homozygous missense mutation 331Gly to Ser.
Colitis
Unconjugated bilirubin ameliorates the inflammation and digestive protease increase in TNBS-induced colitis.
Colitis, Ulcerative
Colonic proteinases: increased activity in patients with ulcerative colitis.
Colitis, Ulcerative
Pancreatic and granulocytic endoproteases in faecal extracts from patients with active ulcerative colitis.
Colonic Diseases
[Trypsin and chymotrypsin in the differential diagnosis of inflammatory colonic diseases]
Colorectal Neoplasms
Serine protease modulation of Dependence Receptors and EMT protein expression.
Common Cold
[Alpha-chymotrypsin in tubal catarrh and chronic otitis. Complications and sequelae. Technic and results.]
Common Cold
[Chymotrypsin in the treatment of chronic catarrh and adhesive otitis in children]
Corneal Dystrophies, Hereditary
Influence of alpha chymotrypsin of endothelial corneal dystrophy.
Corneal Dystrophies, Hereditary
Influence of alpha-chymotrypsin on endothelial corneal dystrophy.
Corneal Injuries
[Experimental studies on corneal injuries by alpha-chymotrypsin and trypsin.]
Corneal Injuries
[EXPERIMENTAL STUDIES ON CORNEAL INJURY DUE TO ALPHA-CHYMOTRYPSIN. A CONTRIBUTION TO THE PROTECTIVE FUNCTION OF THE ENDOTHELIUM.]
Corneal Perforation
Corneal perforation in metaherpetic keratitis with virus inclusions treated with alpha chymotrypsin.
Crohn Disease
Levels of trypsin and alpha-chymotrypsin in feces from patients with Crohn's disease.
Crohn Disease
Usefulness of random fecal alpha 1-antitrypsin and chymotrypsin determinations in children.
Cystic Fibrosis
Chymotryptic activity in stool of low birth weight infants in the first week of life.
Cystic Fibrosis
Diagnosis of exocrine pancreatic insufficiency in cystic fibrosis by use of fluorescein dilaurate test.
Cystic Fibrosis
Effect of pancreozymin and secretin on intraluminal enterokinase, trypsin, and chymotrypsin activities of cystic fibrosis and control children.
Cystic Fibrosis
Faecal chymotrypsin concentrations in neonates with cystic fibrosis and healthy controls.
Cystic Fibrosis
Fecal chymotrypsin: a new diagnostic test for exocrine pancreatic insufficiency in children with cystic fibrosis.
Cystic Fibrosis
Fecal elastase-1 is superior to fecal chymotrypsin in the assessment of pancreatic involvement in cystic fibrosis.
Cystic Fibrosis
Immunoreactive trypsin, chymotrypsin, and pancreatic secretory trypsin inhibitor in cord blood from infants with cystic fibrosis.
Cystic Fibrosis
Indirect parameters of pancreatic function in cystic fibrosis (CF) during a controlled double-blind trial of pancreatic supplementation.
Cystic Fibrosis
Levels and molecular forms of immunoreactive trypsin and chymotrypsin in amniotic fluids from normal and cystic fibrosis fetus: evidence for a lack of activation of proteolytic zymogens in cystic fibrosis fetus.
Cystic Fibrosis
Rapid semiquantitative tests for trypsin and chymotrypsin application to screening for cystic fibrosis, enterokinase deficiency and pancreatic hypoplasia in neonates.
Cystic Fibrosis
Secretin pancreozymin stimulation test and confirmation of the diagnosis of cystic fibrosis.
Cystic Fibrosis
Sensitivity assessment of chymotrypsin faecal test in controlling malabsorption in cystic fibrosis.
Cystic Fibrosis
Stool trypsin and chymotrypsin. Value in the diagnosis of pancreatic insufficiency in cystic fibrosis.
Cystic Fibrosis
The assay of chymotrypsin in stool as a simple and effective test of exocrine pancreatic activity in cystic fibrosis.
Cystic Fibrosis
Titrimetric measurements of fecal trypsin and chymotrypsin in cystic fibrosis with pancreatic exocrine insufficiency.
Cystic Fibrosis
Usefulness of random fecal alpha 1-antitrypsin and chymotrypsin determinations in children.
Cystic Fibrosis
[Reduced activity of chymotrypsin in cystic fibrosis of the pancreas: enzyme deficiency or inactivated enzyme?]
Cysts
Acinar cell cystadenoma of the pancreas: a benign neoplasm or non-neoplastic ballooning of acinar and ductal epithelium?
Cysts
Detection of trypsin- and chymotrypsin-like proteases using p-nitroanilide substrates after sodium dodecyl sulphate polyacrylamide gel electrophoresis.
Cysts
Giardia cyst wall protein 1 is a lectin that binds to curled fibrils of the GalNAc homopolymer.
Cysts
Isolation and culture of rhesus monkey pancreatic ductules and ductule-like epithelium.
Dacryocystitis
[A combined use of alpha-chymotrypsin with corticosteroids in the treatment of chronic dacryocystitis and lacrimal duct stenosis]
Dehydration
Effect of dioxane on the structure and hydration-dehydration of alpha-chymotrypsin as measured by FTIR spectroscopy.
Dehydration
[Anomalous temperature dependence of the activity of immobilized alpha-chymotrypsin preparations]
Dementia, Vascular
Cerebrospinal fluid of patients with senile dementia of Alzheimer's type shows an increased inhibition of alpha-chymotrypsin.
Dengue
NMR and MD Studies Reveal That the Isolated Dengue NS3 Protease Is an Intrinsically Disordered Chymotrypsin Fold Which Absolutely Requests NS2B for Correct Folding and Functional Dynamics.
Dengue
Structurally- and dynamically-driven allostery of the chymotrypsin-like proteases of SARS, Dengue and Zika viruses.
Diabetes Mellitus, Type 1
Exocrine pancreatic function in tropical fibrocalculous pancreatic diabetes.
Diabetes Mellitus, Type 2
Exocrine pancreatic function in tropical fibrocalculous pancreatic diabetes.
Diabetes Mellitus, Type 2
Nutritional markers in patients with diabetes and pancreatic exocrine failure.
Duodenogastric Reflux
Short-term inhibition of duodenal tryptic activity does not affect human pancreatic, biliary, or gastric function.
Encephalitis, Tick-Borne
Immunogenicity of tick-borne encephalitis virus glycoprotein fragments: epitope-specific analysis of the antibody response.
Encephalomyelitis
Anti-inflammatory effect of chymotrypsin to autoimmune response against CNS is dose-dependent.
Encephalomyelitis, Autoimmune, Experimental
Anti-inflammatory effect of chymotrypsin to autoimmune response against CNS is dose-dependent.
Endometrial Neoplasms
Characterization of a 54 kDa, alpha 1-antitrypsin-like protein isolated from ascitic fluid of an endometrial cancer patient.
Endometriosis
A clinical pregnancy after a simple method of zona cutting, cryopreservation, and zygote intrafallopian transfer.
enteropeptidase deficiency
Rapid semiquantitative tests for trypsin and chymotrypsin application to screening for cystic fibrosis, enterokinase deficiency and pancreatic hypoplasia in neonates.
Epidermolysis Bullosa, Junctional
Elevated serum chymotrypsin levels in a patient with junctional epidermolysis bullosa. Normalization after UVB therapy with good clinical response.
Exocrine Pancreatic Insufficiency
13C-starch breath test--comparative clinical evaluation of an indirect pancreatic function test.
Exocrine Pancreatic Insufficiency
A new faecal chymotrypsin method for evaluating the exocrine pancreatic function in patients with different pancreatic diseases.
Exocrine Pancreatic Insufficiency
A new method of testing pancreatin therapy in vivo by the use of a peroral chymotrypsin substrate 4-(N-acetyl-L-tyrosyl)aminobenzoic acid.
Exocrine Pancreatic Insufficiency
A single-specimen fecal chymotrypsin test in the diagnosis of pancreatic insufficiency: correlation with secretin-cholecystokinin and NBT-PABA tests.
Exocrine Pancreatic Insufficiency
Adequate enzymatic substitution in treating exocrine pancreatic insufficiency.
Exocrine Pancreatic Insufficiency
Biochemical tests in the diagnosis of chronic pancreatitis and in the evaluation of pancreatic insufficiency.
Exocrine Pancreatic Insufficiency
Comparative clinical evaluation of the 13C-mixed triglyceride breath test as an indirect pancreatic function test.
Exocrine Pancreatic Insufficiency
Diagnostic Performance of Measurement of Fecal Elastase-1 in Detection of Exocrine Pancreatic Insufficiency: Systematic Review and Meta-analysis.
Exocrine Pancreatic Insufficiency
Diagnostic value of the fecal chymotrypsin test in pancreatic insufficiency, particularly chronic pancreatitis: correlation with the pancreozymin-secretin test, fecal fat excretion and final clinical diagnosis.
Exocrine Pancreatic Insufficiency
Exocrine pancreatic function in tropical fibrocalculous pancreatic diabetes.
Exocrine Pancreatic Insufficiency
Faecal chymotrypsin assay in tropical and alcoholic chronic pancreatitis.
Exocrine Pancreatic Insufficiency
Faecal elastase 1: a novel, highly sensitive, and specific tubeless pancreatic function test.
Exocrine Pancreatic Insufficiency
Faecal elastase 1: not helpful in diagnosing chronic pancreatitis associated with mild to moderate exocrine pancreatic insufficiency.
Exocrine Pancreatic Insufficiency
Failure to thrive: the earliest feature of cystic fibrosis in infants diagnosed by neonatal screening.
Exocrine Pancreatic Insufficiency
Fecal chymotrypsin and elastase-1 determination on one single stool collected at random: diagnostic value for exocrine pancreatic status.
Exocrine Pancreatic Insufficiency
Fecal chymotrypsin levels in children with pancreatic insufficiency.
Exocrine Pancreatic Insufficiency
Fecal chymotrypsin: a new diagnostic test for exocrine pancreatic insufficiency in children with cystic fibrosis.
Exocrine Pancreatic Insufficiency
Fecal elastase-1 as a test for pancreatic function: a review.
Exocrine Pancreatic Insufficiency
Fecal elastase-1 determination: 'gold standard' of indirect pancreatic function tests?
Exocrine Pancreatic Insufficiency
Improved sensitivity of the BTPABA pancreatic function test in animals with meals of raw egg white.
Exocrine Pancreatic Insufficiency
Molecular Dynamics-Guided Design of a Functional Protein-ATRP Conjugate That Eliminates Protein-Protein Interactions.
Exocrine Pancreatic Insufficiency
Now that fecal elastase is available in the United States, should clinicians start using it?
Exocrine Pancreatic Insufficiency
Pancreatic function tests in the rat model of chronic pancreatic insufficiency.
Exocrine Pancreatic Insufficiency
Proteases in the evaluation of pancreatic function and pancreatic disease.
Exocrine Pancreatic Insufficiency
Specificity of the BT-PABA test for the diagnosis of exocrine pancreatic insufficiency in the dog.
Exocrine Pancreatic Insufficiency
Stool trypsin and chymotrypsin. Value in the diagnosis of pancreatic insufficiency in cystic fibrosis.
Exocrine Pancreatic Insufficiency
The effect of exocrine pancreatic function on chloramphenicol pharmacokinetics in patients with cystic fibrosis.
Exocrine Pancreatic Insufficiency
Total pancreatic insufficiency in pigs: a model to study intestinal enzymes and plasma levels of digestive hormones after pancreatic supplementation by a whole pancreas preparation.
Exocrine Pancreatic Insufficiency
Usefulness of random fecal alpha 1-antitrypsin and chymotrypsin determinations in children.
Exocrine Pancreatic Insufficiency
[Determination and clinical relevance of fecal pancreatic elastase in dogs]
Exocrine Pancreatic Insufficiency
[Determination of chymotrypsin in feces and the peptide-PABA test in exocrine pancreatic insufficiency]
Exocrine Pancreatic Insufficiency
[Determination of chymotrypsin in feces as screening method for exocrine pancreatic insufficiency]
Exocrine Pancreatic Insufficiency
[Determination of fecal chymotrypsin as a screening test for exocrine pancreatic insufficiency: studies on the reliability of various methods]
Exocrine Pancreatic Insufficiency
[DETERMINATION OF TRYPSIN AND CHYMOTRYPSIN ACTIVITY IN STOOLS. A SPECIFIC SENSITIVE METHOD FOR THE DEMONSTRATION OF EXOCRINE PANCREATIC INSUFFICIENCY.]
Exocrine Pancreatic Insufficiency
[Diagnosis of pancreatic diseases in childhood (author's transl)]
Exocrine Pancreatic Insufficiency
[Evaluation of exocrine pancreatic insufficiency in cirrhotic patients,using the fecal chymotrypsin test]
Exocrine Pancreatic Insufficiency
[Exocrine pancreatic insufficiency. Chymotrypsin determination and peptide PABA test]
Exocrine Pancreatic Insufficiency
[Fecal chymotrypsin test in the diagnosis of pancreatic insufficiency]
Exocrine Pancreatic Insufficiency
[Measurement of fecal chymotrypsin. Clinical and methodological aspects (author's transl)]
Exocrine Pancreatic Insufficiency
[Modified ALTAB test in the diagnosis of exocrine pancreatic insufficiency]
Exocrine Pancreatic Insufficiency
[On the determination of trypsin and chymotrypsin activity in the feces of dogs and their significance in the diagnosis of chronic exocrine pancreatic insufficiency]
Exocrine Pancreatic Insufficiency
[Photometric determination of chymotrypsin in feces of the dog. A new method in the diagnosis of chronic exocrine pancreatic insufficiency]
Exocrine Pancreatic Insufficiency
[Serum paraaminobenzoic acid following the use of N-benzoyl-L-tyrosyl-paraaminobenzoic acid in the diagnosis of pancreatic insufficiency]
Exocrine Pancreatic Insufficiency
[Significance of immunoreactive lipase in the diagnosis of pancreatic diseases]
Exocrine Pancreatic Insufficiency
[The PABA-peptide test: a method in diagnosis of exocrine pancreatic insufficiency (author's transl)]
Eye Hemorrhage
[Lens dislocation into the vitreous body after intravitreal administration of chymotrypsin in hemophthalmos]
Fallopian Tube Diseases
[Feminine sterility of tubal obstruction treated with alpha-chymotrypsin and antibiotics]
Fetal Resorption
Preliminary evaluation of maternotoxic effect of Ascaris alpha-chymotrypsin inhibitor in mice.
Foot-and-Mouth Disease
Effect of trypsin and chymotrypsin on the polypeptides of large and small plaque variants of foot-and-mouth disease virus: relationship to specific antigenicity and infectivity.
Foot-and-Mouth Disease
Immunogenic and cell attachment sites of FMDV: further evidence for their location in a single capsid polypeptide.
Foot-and-Mouth Disease
The influence of the host cell, ionic strength and chymotrypsin on foot-and-mouth disease virus electrophoretic mobility.
Gastroenteritis
Usefulness of random fecal alpha 1-antitrypsin and chymotrypsin determinations in children.
Gastrointestinal Diseases
Comparative clinical evaluation of the 13C-mixed triglyceride breath test as an indirect pancreatic function test.
Gastrointestinal Diseases
Faecal elastase 1: a novel, highly sensitive, and specific tubeless pancreatic function test.
Giardiasis
Secretin-cerulein test and fecal chymotrypsin concentration in children with intestinal giardiasis.
Glaucoma
Dose relationship of alpha chymotrypsin in production of glaucoma after cataract extraction.
Glaucoma
Experimental glaucoma significantly decreases atrial natriuretic factor (ANF) receptors in the ciliary processes of the rabbit eye.
Glaucoma
Further studies on glaucoma following cataract extraction associated with the use of alpha-chymotrypsin.
Glaucoma
Immunoreactive atrial natriuretic factor in aqueous humor: its concentration is increased with high intraocular pressure in rabbit eyes.
Glaucoma
Oculohypotensive effect of angiotensin-converting enzyme inhibitors in acute and chronic models of glaucoma.
Glaucoma
The effect of pneumoperitoneum on intraocular pressure in rabbits with alpha-chymotrypsin-induced glaucoma.
Glaucoma
[Effects of trabeculectomy combined with amniotic membrane and extracellular matrix of conjunctiva on filtering bleb in rabbits eyes]
Glaucoma
[Experimental alpha-chymotrypsin model of glaucoma in the rabbit: histopathological studies (author's transl)]
Glaucoma
[Shunt tube implantation combining amniotic membrane transplantation and implantation of Molteno implant for glaucoma after penetrating keratoplasty]
Glioma
Interleukin-2 and lymphokine activated killer (LAK) cells in the treatment of malignant glioma: clinical and experimental studies.
Glioma
Lymphokine activated killer (LAK) cell mediated killing of human glioma: effect of pretreating glioma with various membrane modifying agents.
Glioma
Lymphokine activated killer (LAK) cell-mediated lysis of murine glioma: trypsin-chymotrypsin-sensitive glioma protein is responsible for tumor-selective recognition by LAK cells.
Glomerulonephritis
[Affinity sorbents with tripeptide morpholine ligands for isolation of proteases]
Gonorrhea
[Functional indices of the hypophysis, gonads and adrenal cortex during the treatment of patients with gonorrheal inflammation of the scrotal organs using proteolytic enzymes]
Granuloma
[Influence of alpha-chymotrypsin on the distribution of tritiated tetracycline in rats with an experimental granuloma]
Granuloma
[The pharmacokinetics of kanamycin, including granuloma penetration, in rats treated with chymotrypsin]
Granulomatous Disease, Chronic
Cytochemical determination of granulocyte elastase and chymotrypsin in human myeloid cells and its application in acquired deficiency states and diagnosis of myeloid leukemia.
Graves Disease
Prevalence and significance of steatorrhea in patients with active Graves' disease.
Heart Failure
Nutritional leucine supplementation attenuates cardiac failure in tumour-bearing cachectic animals.
Hemophilia B
Characterisation of factor IX with a glycine-to-valine missense mutation at residue 190 in a patient with severe haemophilia B.
Hepatitis A
Protease digestion of hepatitis A virus: disparate effects on capsid proteins, antigenicity, and infectivity.
Hepatitis B
Entry of duck hepatitis B virus into primary duck liver and kidney cells after discovery of a fusogenic region within the large surface protein.
Hepatitis C
Structure-activity relationships for the selectivity of hepatitis C virus NS3 protease inhibitors.
Herpes Simplex
The unique N terminus of the herpes simplex virus type 1 large subunit is not required for ribonucleotide reductase activity.
Herpes Zoster
A clinical pregnancy after a simple method of zona cutting, cryopreservation, and zygote intrafallopian transfer.
Herpes Zoster
A survey of the effects of proteases and glycosidases on culture of rabbit morulae to blastocysts.
Herpes Zoster
Beneficial effect of serum on the fertilizability of mouse oocytes matured in vitro.
Herpes Zoster
Blocking of human sperm-zona interaction by monoclonal antibodies to a glycoprotein family (ZP4) of porcine zona pellucida.
Herpes Zoster
Characterization of the binding of recombinant mouse sperm fertilin beta subunit to mouse eggs: evidence for adhesive activity via an egg beta1 integrin-mediated interaction.
Herpes Zoster
Clinical evaluation of three approaches to micromanipulation-assisted fertilization.
Herpes Zoster
Collagenase as an agent for dissolving the zona pellucida of hamster and mouse oocytes.
Herpes Zoster
Comparison of embryonic developmental competence of mouse oocytes grown with and without serum.
Herpes Zoster
Cortical reaction and zona hardening in mouse oocytes following exposure to ethanol.
Herpes Zoster
Cytoskeletal organization and zona sensitivity to digestion by chymotrypsin of frozen-thawed mouse oocytes.
Herpes Zoster
Effect of treating sperm with low hypo-osmotic swelling test scores with chymotrypsin on pregnancy rates after conventional in vitro fertilization-embryo transfer.
Herpes Zoster
Effects of fetuin on zona pellucida hardening, fertilization and embryo development in cattle.
Herpes Zoster
Enzymatic characterization of zona pellucida hardening in human eggs and embryos.
Herpes Zoster
Fetal calf serum increased the zona pellucida penetrability of rat oocytes matured in vitro.
Herpes Zoster
Fetuin inhibits zona pellucida hardening and conversion of ZP2 to ZP2f during spontaneous mouse oocyte maturation in vitro in the absence of serum.
Herpes Zoster
Hardening of zona pellucida of mouse oocytes and embryos in vivo and in vitro.
Herpes Zoster
Investigation of some antimicrobial procedures on the in vitro development of early murine embryos aimed toward developing methods for the disinfection of mammalian embryos prior to transfer.
Herpes Zoster
Maturation of hamster oocytes under chemically defined conditions and sperm penetration through the zona pellucida.
Herpes Zoster
Mouse egg extracellular coat is a matrix of interconnected filaments possessing a structural repeat.
Herpes Zoster
Oocyte proteomics: localisation of mouse zona pellucida protein 3 to the plasma membrane of ovulated mouse eggs.
Herpes Zoster
Sperm penetration of rat eggs in vitro after dissolution of zona pellucida by chymotrypsin.
Herpes Zoster
Studies on zona hardening in rat oocytes that are matured in vitro in a serum-free medium.
Herpes Zoster
The effect on fertilization of exposure of mouse oocytes to dimethyl sulfoxide: an optimal protocol.
Herpes Zoster
The influence of cooling on the properties of the zona pellucida of the mouse oocyte.
Herpes Zoster
Zona pellucida solubility and cortical granule complements in human oocytes following assisted reproductive techniques.
Hyperinsulinism
Relationship between circulating levels of pancreatic proteolytic enzymes and pancreatic hormones.
Hyperlipidemias
Blood lipids, fecal fat and chymotrypsin excretion in the dog: influence of age, body weight and sex.
Hypersensitivity
The role of amino-terminal alanine in the control of conformation and activity of alpha-chymotrypsin.
Hypersensitivity
[Anaphylactoid reaction to trypsin following local administration of Dontisolon ointment]
Hypertension
Antioxidant status in rabbit aqueous humor after instillation of ascorbyl laurate-based nanostructures.
Hypertension
Renin inhibitors. Improvements in the stability and biological activity of small peptides containing novel Leu-Val replacements.
Hypertension
[Effect of timolol and acetazolamide on intraocular hypertension after intracapsular lens extraction with alpha-chymotrypsin (author's transl)]
Hypothyroidism
Protease inhibitors in sera as possible indicators of familial hypothyroidism.
Hypotrichosis
Autosomal ichthyosis with hypotrichosis syndrome displays low matriptase proteolytic activity and is phenocopied in ST14 hypomorphic mice.
Ichthyosis
Autosomal ichthyosis with hypotrichosis syndrome displays low matriptase proteolytic activity and is phenocopied in ST14 hypomorphic mice.
Infections
A protein secreted in vivo by Echinococcus granulosus inhibits elastase activity and neutrophil chemotaxis.
Infections
Action of chymotrypsin on experimental Plasmodium berghei infection in albino mice.
Infections
Analysis of Rickettsia typhi-infected and uninfected cat flea (Ctenocephalides felis) midgut cDNA libraries: deciphering molecular pathways involved in host response to R. typhi infection.
Infections
Cells and viruses with mutations affecting viral entry are selected during persistent infections of L cells with mammalian reoviruses.
Infections
Changes in the intestinal enzyme activity of lambs during chronic infection with Trichostrongylus vitrinus.
Infections
Characterization of avian reovirus-induced cell fusion: the role of viral structural proteins.
Infections
Cytoplasmic trafficking of minute virus of mice: low-pH requirement, routing to late endosomes, and proteasome interaction.
Infections
Evaluation of a protease activation mutant of Sendai virus as a potent live vaccine.
Infections
Identification of the 33-kDa alkaline protease of Aspergillus fumigatus in vitro and in vivo.
Infections
Intact intestinal mRNAs and intestinal epithelial cell esterase, but not Cryptosporidium parvum, reach mesenteric lymph nodes of infected mice.
Infections
Isolation and characterization of phagosomes containing Chlamydia psittaci from L cells.
Infections
Metarhizium anisopliae host-pathogen interaction: differential immunoproteomics reveals proteins involved in the infection process of arthropods.
Infections
Negative Pressure Wound Therapy With Chymotrypsin Irrigation: A Maximal Implant Retention Procedure Treating the Exposure/Infection of Titanium Mesh in Cranioplasty.
Infections
Prevention of catheter-related infections by a new, catheter-restricted antibiotic filling technique.
Infections
Reduced Virion-Associated ?1 Fibers on Oncolytic Reovirus Variants Promotes Adaptation towards Tumorigenic Cells.
Infections
Role of inhibitors of serine peptidases in protecting Leishmania donovani against the hydrolytic peptidases of sand fly midgut.
Infections
Stunting syndrome in broilers: effect of glucose or maltose supplementation on digestive organs, intestinal disaccharidases, and some blood metabolites.
Infections
Toward the physiological basis for increased Agrotis ipsilon multiple nucleopolyhedrovirus infection following feeding of Agrotis ipsilon larvae on transgenic corn expressing Cry1Fa2.
Infections
Transient high level mammalian reovirus replication in a bat epithelial cell line occurs without cytopathic effect.
Infections
Xylanase supplementation of a wheat-based diet improved nutrient digestion and mRNA expression of intestinal nutrient transporters in broiler chickens infected with Clostridium perfringens.
Infections
[Clinical evaluation of the effect of a combination of tetracycline-L-methylenbysine with trypsin and alpha-chymotrypsin on acute and chronic oral infections]
Infections
[Studies on the increase of weights of lymphatic glands, of lymph and peritoneal fluid and their contents of chymotrypsin and virus in pigs suffering hog cholera (author's transl)]
Infections
[The treatment of urinary tract infection following transurethral prostatic resection by use of alpha-chymotrypsin enteric-coated tablet]
Infertility
[Feminine sterility of tubal obstruction treated with alpha-chymotrypsin and antibiotics]
Infertility
[Treatment of tubal infertility by combined abdominal vacuum decompression, hydrotubation and the intramuscular administration of chymotrypsin]
Infertility
[Treatment of tubal sterility by means of abdominal vacuum decompression in combination with hydrotubation and the intramuscular administration of chymotrypsin]
Infertility, Male
[Shenfu Qiangjing decoction improves non-inflammatory and non-liquefied semen in kidney-yang deficiency men]
Influenza, Human
Improved data visualization techniques for analyzing macromolecule structural changes.
Keratitis
Corneal perforation in metaherpetic keratitis with virus inclusions treated with alpha chymotrypsin.
Keratitis
DISCUSSION OF THE POSSIBLE MECHANISMS OF ACTION OF 5-IODO-2'-DEOXYURIDINE (IDU,IUDR) AND CHYMOTRYPSIN IN THE TREATMENT OF HERPES SIMPLEX KERATITIS.
Keratitis, Dendritic
FURTHER EVALUATION OF THE USE OF CHYMOTRYPSIN IN THE TREATMENT OF DENDRITIC KERATITIS.
Keratitis, Herpetic
DISCUSSION OF THE POSSIBLE MECHANISMS OF ACTION OF 5-IODO-2'-DEOXYURIDINE (IDU,IUDR) AND CHYMOTRYPSIN IN THE TREATMENT OF HERPES SIMPLEX KERATITIS.
Ketosis
Ketosis resistant diabetes of the young: a profile of its exocrine and endocrine pancreatic dysfunction.
Kidney Diseases
[Usefulness of the peroral test with the chymotrypsin substrate 4-(N-acetyl-L-tyrosyl)aminobenzoic acid in patients with kidney diseases]
Kidney Failure, Chronic
Alterations of exocrine pancreas in end-stage renal disease. Do they reflect a clinically relevant uremic pancreopathy?
Kwashiorkor
Exocrine pancreatic function of children from the Ivory Coast compared to French children. Effect of kwashiorkor.
Leg Ulcer
Degradation of eschar from venous leg ulcers using a recombinant chymotrypsin from Lucilia sericata.
Lens Subluxation
[Lens dislocation into the vitreous body after intravitreal administration of chymotrypsin in hemophthalmos]
Leukemia
Bromelain proteinases modulate the cd44 expression on human molt-4/8 leukemia and sk-mel-28 melanoma-cells in-vitro.
Leukemia
Characterization of glucocorticoid receptors and glucocorticoid receptor mRNA in human leukemia cells: stabilization of the receptor by diisopropylfluorophosphate.
Leukemia
Heterogeneity of cell surface structures involved in cytotoxicity mediated by lymphokine activated killer cells.
Leukemia
Human T-cell leukemia-associated cell surface glycoprotein GP37: studies with three monoclonal antibodies and a rabbit antiserum.
Leukemia, Myeloid
Cytochemical determination of granulocyte elastase and chymotrypsin in human myeloid cells and its application in acquired deficiency states and diagnosis of myeloid leukemia.
Liver Cirrhosis, Alcoholic
Pancreatic secretion after secretin and cholecystokinin stimulation in chronic alcoholics with and without cirrhosis.
Liver Neoplasms
Inhibitory properties of camel whey protein hydrolysates toward liver cancer cells, dipeptidyl peptidase-IV, and inflammation.
Lung Injury
Suppression of superantigen-induced lung injury and vasculitis by preadministration of human urinary trypsin inhibitor.
Lung Neoplasms
Identification and Target-Modification of SL-BBI: A Novel Bowman-Birk Type Trypsin Inhibitor from Sylvirana latouchii.
Lung Neoplasms
Jizanpeptins, Cyanobacterial Protease Inhibitors from a Symploca sp. Cyanobacterium Collected in the Red Sea.
Lung Neoplasms
The use of chymotrypsin for the concentration of sputum in the cytologic diagnosis of lung cancer.
Lymphoma
Absence in glucocorticoid-resistant mouse lymphoma P1798 of a glucocorticoid receptor domain responsible for biological effects.
Lymphoma, B-Cell
Evidence for a functional receptor for cyclosporin A on the surface of lymphocytes.
Malaria
Analysis of Erythrocyte Invasion Mechanisms of Plasmodium falciparum Clinical Isolates Across 3 Malaria-Endemic Areas in Ghana.
Malaria
Chymotrypsin genes in the malaria mosquitoes Anopheles aquasalis and Anopheles darlingi.
Malaria
Erythrocyte invasion and merozoite ligand gene expression in severe and mild Plasmodium falciparum malaria.
Malaria
Expression and characterisation of Plasmodium falciparum acidic basic repeat antigen expressed in Escherichia coli.
Malnutrition
Comparative changes between pancreas and pancreatic juice digestive enzyme contents during nutritional rehabilitation following severe protein malnutrition in the rat.
Mastocytoma
Characterisation of tryptase and a granzyme H-like chymase isolated from equine mastocytoma tissue.
Maxillary Sinusitis
[Enzymatic study on the mucus membrane in upper maxillary sinusitis and the effects of radioactive iodine-labelled alpha-chymotrypsin on protease activity]
Maxillary Sinusitis
[Treatment of chronic maxillary sinusitis by sinus lavage, alpha-chymotrypsin instillations and an appropriate antibiotic.]
Measles
[Intramuscular alpha-chymotrypsin in the treatment of acute obstructive respiratory syndrome of the child, as a complication of measles]
Meconium Ileus
Faecal chymotrypsin concentrations in neonates with cystic fibrosis and healthy controls.
Melanoma
Heterogeneity of cell surface structures involved in cytotoxicity mediated by lymphokine activated killer cells.
Melanoma
Mixture of trypsin, chymotrypsin and papain reduces formation of metastases and extends survival time of C57Bl6 mice with syngeneic melanoma B16.
Melanoma
Polyenzyme preparation Wobe-Mugos inhibits growth of solid tumors and development of experimental metastases in mice.
Melanoma
Role of the alpha 5 beta 1 integrin receptor in the proliferative response of quiescent human melanoma cells to fibronectin.
Melanoma, Experimental
Mixture of trypsin, chymotrypsin and papain reduces formation of metastases and extends survival time of C57Bl6 mice with syngeneic melanoma B16.
Multiple Sclerosis
Anti-inflammatory effect of chymotrypsin to autoimmune response against CNS is dose-dependent.
Mumps
Conversion of nonfusing mumps virus infections to fusing infections by selective proteolysis of the HN glycoprotein.
myeloperoxidase deficiency
Cytochemical determination of granulocyte elastase and chymotrypsin in human myeloid cells and its application in acquired deficiency states and diagnosis of myeloid leukemia.
Myotonic Dystrophy
Leukocyte protease activities in myotonic dystrophy: studies on effects of protease inhibitors.
Neoplasm Metastasis
Antiproliferative activity of Lavatera cashmeriana- protease inhibitors towards human cancer cells.
Neoplasm Metastasis
Deoxyribonuclease treatment prevents blood-borne liver metastasis of cutaneously transplanted tumour cells in mice.
Neoplasm Metastasis
Effects of serine protease and deoxyribonuclease on intravascular tumor cell arrest in rat blood-borne lung metastasis.
Neoplasm Metastasis
Mixture of trypsin, chymotrypsin and papain reduces formation of metastases and extends survival time of C57Bl6 mice with syngeneic melanoma B16.
Neoplasm Metastasis
Serine protease-induced enhancement of blood-borne metastasis of rat ascites tumour cells and its prevention with deoxyribonuclease.
Neoplasms
A primary pure pancreatic-type acinar cell carcinoma of the stomach: a case report.
Neoplasms
Acinar cell carcinoma of the pancreas metastatic to the ovary: a report of 4 cases.
Neoplasms
Antimetastatic activity of boro-amino acid analog protease inhibitors against B16BL6 melanoma in vivo.
Neoplasms
Antiproliferative activity of Lavatera cashmeriana- protease inhibitors towards human cancer cells.
Neoplasms
Chymotrypsin B Cached in Rat Liver Lysosomes and Involved in Apoptotic Regulation through a Mitochondrial Pathway.
Neoplasms
Cytomorphologic and immunophenotypical features of acinar cell neoplasms of the pancreas.
Neoplasms
Degradation of immobilized soluble elastin by tumor cells in culture: quantitation by ELISA.
Neoplasms
Deoxyribonuclease treatment prevents blood-borne liver metastasis of cutaneously transplanted tumour cells in mice.
Neoplasms
Differential effects of serine proteases on the migration of normal and tumor cells: implications for tumor microenvironment.
Neoplasms
Differential release of active proteinase inhibitors by two rat mammary adenocarcinoma variants possessing different metastatic potentials.
Neoplasms
Effect of administration of crystalline chymotrypsin upon the Beard test for malignancy.
Neoplasms
Effect of the gastrin-releasing peptide antagonist BIM 26226 and lanreotide on an acinar pancreatic carcinoma.
Neoplasms
Effects of serine protease and deoxyribonuclease on intravascular tumor cell arrest in rat blood-borne lung metastasis.
Neoplasms
Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition.
Neoplasms
Evidence for the inhibition of trypsin by thiols. The mechanism of enzyme-inhibitor complex formation.
Neoplasms
Exogenous proteases confer a significant chemopreventive effect in experimental tumor models.
Neoplasms
Interleukin-2 and lymphokine activated killer (LAK) cells in the treatment of malignant glioma: clinical and experimental studies.
Neoplasms
Intraductal Tubulopapillary Neoplasm of the Pancreas Masquerading as Pancreatic Neuroendocrine Carcinoma: Review of the Literature with a Case Report.
Neoplasms
Lymphokine activated killer (LAK) cell mediated killing of human glioma: effect of pretreating glioma with various membrane modifying agents.
Neoplasms
Mining the cinnabaramide biosynthetic pathway to generate novel proteasome inhibitors.
Neoplasms
Mixture of trypsin, chymotrypsin and papain reduces formation of metastases and extends survival time of C57Bl6 mice with syngeneic melanoma B16.
Neoplasms
Non-pancreatic proteases of the chymotrypsin family. II. Two proteases from a mouse mast cell tumor.
Neoplasms
Oral therapy with proteolytic enzymes decreases excessive TGF-beta levels in human blood.
Neoplasms
Pancreatic acinar cell carcinoma. An analysis of cell lineage markers, p53 expression, and Ki-ras mutation.
Neoplasms
Pancreatic secretory abnormalities precede appearance of tumors of the pancreas in hamsters treated with bis-(2-oxopropyl)-N-nitrosamine.
Neoplasms
Pancreatic-type Acinar Cell Carcinoma of the Stomach Included in Multiple Primary Carcinomas.
Neoplasms
Papillary cystic tumor of the pancreas. An analysis of cellular differentiation by electron microscopy and immunohistochemistry.
Neoplasms
Parenteral administration of chymotrypsin for the early detection of cancer cells in sputum.
Neoplasms
Point, minute and small cancers of the stomach at the early developmental stage detected by improved chymotrypsin lavage method for diagnostic cytology.
Neoplasms
Prevalence and prognostic significance of acinar cell differentiation in pancreatic endocrine tumors.
Neoplasms
Selective depletion of tumour suppressors Deleted in Colorectal Cancer (DCC) and neogenin by environmental and endogenous serine proteases: linking diet and cancer.
Neoplasms
Serine protease-induced enhancement of blood-borne metastasis of rat ascites tumour cells and its prevention with deoxyribonuclease.
Neoplasms
Sodium butyrate improved intestinal immune function associated with NF-?B and p38MAPK signalling pathways in young grass carp (Ctenopharyngodon idella).
Neoplasms
Stimulation of reactive oxygen species production and cytotoxicity in human neutrophils in vitro and after oral administration of a polyenzyme preparation.
Neoplasms
Symplocamide A, a potent cytotoxin and chymotrypsin inhibitor from the marine Cyanobacterium Symploca sp.
Neoplasms
The cytologic diagnosis of gastric cancer of chymotrypsin lavage. II. The detection of early malignancy.
Neoplasms
The effect of administration of crystalline chymotrypsin upon placental transplants, spontaneous tumors and Jensen sarcoma in rats.
Neoplasms
The prevalence of pancreatic acinar differentiation in gastric adenocarcinoma: report of a case and immunohistochemical study of 111 additional cases.
Neoplasms
[Chymotripsin-like activity and subunit composition of proteasomes in human cancers].
Neoplasms
[Reactions of derivatives of beta-lactam antibiotics with non-antibacterial biological activity]
Neoplasms
[Successful Surgical Resection of Expansive-Growth Acinar Cell Carcinoma-A Case Report].
Neoplasms
[Use of chymotrypsin in the surgical treatment of benign tumors and tumor-like diseases of the bones in children]
Neuroblastoma
Evidence that neutral sphingomyelinase of cultured murine neuroblastoma cells is oriented externally on the plasma membrane.
Neurodegenerative Diseases
Effects of [6]-shogaol on cholinergic signaling in HT22 cells following neuronal damage induced by hydrogen peroxide.
Newcastle Disease
Crystallization of Newcastle disease virus hemagglutinin-neuraminidase glycoprotein.
Ocular Hypertension
A water-soluble carbon monoxide-releasing molecule (CORM-3) lowers intraocular pressure in rabbits.
Ocular Hypertension
Aqueous humor dynamics in alpha-chymotrypsin-induced ocular hypertensive rabbits.
Ocular Hypertension
Hemin, an inducer of heme oxygenase-1, lowers intraocular pressure in rabbits.
Ocular Hypertension
Ocular hypotensive action of topical flunarizine in the rabbit: role of sigma 1 recognition sites.
Ocular Hypertension
Oculohypotensive effect of angiotensin-converting enzyme inhibitors in acute and chronic models of glaucoma.
Ocular Hypertension
Oculohypotensive effect of perindopril in acute and chronic models of glaucoma in rabbits.
Ocular Hypertension
The effect of topical CS-088, an angiotensin AT1 receptor antagonist, on intraocular pressure and aqueous humor dynamics in rabbits.
Ocular Hypertension
The effect of topical dihydroergocristine on the intraocular pressure in alpha-chymotrypsin-induced ocular hypertensive rabbits.
Ocular Hypertension
Topical application of a nitric oxide synthase inhibitor reduces intraocular pressure in rabbits with experimental glaucoma.
Ocular Hypertension
[Experimental alpha-chymotrypsin model of glaucoma in the rabbit: histopathological studies (author's transl)]
Opportunistic Infections
Pancreatic dysfunction and its association with fat malabsorption in HIV infected children.
Osteochondritis
[Peridural administration of drugs in root-compression forms of lumbar osteochondrosis]
Osteomyelitis
[Clinical application of vacuum sealing drainage combined with chymotrypsin in the treatment of post-traumatic mandibular osteomyelitis].
Osteosarcoma
Molecular mechanisms of Polyphyllin I-induced apoptosis and reversal of the epithelial-mesenchymal transition in human osteosarcoma cells.
Otitis
[Alpha-chymotrypsin in tubal catarrh and chronic otitis. Complications and sequelae. Technic and results.]
Otitis Media
THE USE OF ALPHA-CHYMOTRYPSIN IN THE MIDDLE EAR IN MUCOID OTITIS MEDIA (GLUE EAR).
Ovarian Cysts
MUC-6 mucin is a major component of "blood group substance" from human ovarian cyst fluid.
Pancreatic Diseases
13C labelled cholesteryl octanoate breath test for assessing pancreatic exocrine insufficiency.
Pancreatic Diseases
A new faecal chymotrypsin method for evaluating the exocrine pancreatic function in patients with different pancreatic diseases.
Pancreatic Diseases
Activities of gamma-glutamyl transferase, 5'-nucleotidase and alkaline phosphatase in human duodenal aspirate.
Pancreatic Diseases
Biochemical tests in the diagnosis of chronic pancreatitis and in the evaluation of pancreatic insufficiency.
Pancreatic Diseases
Diagnostic value of fecal chymotrypsin and trypsin assessment for detection of pancreatic disease. A comparative study.
Pancreatic Diseases
Label-free fluorometric detection of chymotrypsin activity using graphene oxide/nucleic-acid-stabilized silver nanoclusters hybrid materials.
Pancreatic Diseases
Limitations of faecal elastase-1 and chymotrypsin as tests of exocrine pancreatic disease in adults.
Pancreatic Diseases
MEASUREMENT OF TRYPSIN AND CHYMOTRYPSIN ACTIVITY IN STOOLS TO DETECT CHRONIC PANCREATIC DISEASE.
Pancreatic Diseases
Pancreolauryl test. Evaluation of a tubeless pancreatic function test in comparison with other indirect and direct tests for exocrine pancreatic function.
Pancreatic Diseases
Relationship between PABA and Lundh tests: lack of influence of duodenal pH in vivo.
Pancreatic Diseases
Stool chymotrypsin activity measured by a spectrophotometric procedure to identify pancreatic disease in infants.
Pancreatic Diseases
The fecal chymotrypsin photometric assay in the evaluation of exocrine pancreatic capacity. Comparison with other direct and indirect pancreatic function tests.
Pancreatic Diseases
Thr28, Nle31 CCK-9--an useful CCK analogue in stimulation tests of pancreatic exocrine function.
Pancreatic Diseases
Trypsin and chymotrypsin as aids in the diagnosis of pancreatic disease.
Pancreatic Diseases
Trypsin and chymotrypsin determinations in human duodenal aspirate under the influence of continuous secretin-pancreozymin stimulation as an aid in the diagnosis of pancreatic disease.
Pancreatic Diseases
[Analysis of pancreatic function. Determination of fecal chymotrypsin and the secretin-pancreozymin test. Comparative study]
Pancreatic Diseases
[Critical studies on the diagnostic significance of chymotrypsin determination in pancreatic diseases]
Pancreatic Diseases
[Determination of chymotrypsin in feces using SUPHEPA for the diagnosis of pancreatic diseases]
Pancreatic Diseases
[Determination of chymotrypsin in the stool by succinyl-L-phenylalanin-P-nitraniliden (Suphepa) in the diagnosis of pancreatic diseases (author's transl)]
Pancreatic Diseases
[Determination of chymotrypsin in the stool in chronic pancreatic diseases associated with exocrine insufficiency]
Pancreatic Diseases
[Diagnostic value of chymotrypsin and trypsin activity determination in the feces in the diagnosis of pancreatic disease]
Pancreatic Diseases
[Diagnostic value of fecal chymotrypsin determination in pancreatic diseases]
Pancreatic Diseases
[PABA test versus chymotrypsin and fat determinations in the stool in pancreatic functional diagnosis]
Pancreatic Diseases
[Significance of the evocation test, chymotrypsin and lipid determination in feces for the diagnosis of pancreatic diseases]
Pancreatic Fistula
Pancreatic Chymotrypsin Activity Rather Than Amylase Level Better Predicts Postoperative Pancreatic Fistula.
Pancreatic Fistula
Pancreatic Chymotrypsin Activity Rather Than Amylase Level Better Predicts Postoperative Pancreatic Fistula: Retraction.
Pancreatic Neoplasms
A novel transmembrane serine protease (TMPRSS3) overexpressed in pancreatic cancer.
Pancreatic Neoplasms
Identification of various types of ?2-HS glycoprotein in sera of patients with pancreatic cancer: Possible implication in resistance to protease treatment.
Pancreatitis
"In vivo" and "in vitro" inhibition of human pancreatic chymotrypsin A by serum inhibitors.
Pancreatitis
Acute pancreatitis associated with severe acute respiratory syndrome coronavirus-2 infection: a case report and review of the literature.
Pancreatitis
Associations between gastrointestinal humoral factors and pancreatic proteolytic enzymes in alcohol-related versus non-alcohol-related pancreatitis.
Pancreatitis
Chymotrypsin Reduces the Severity of Secretagogue-Induced Pancreatitis in Mice.
Pancreatitis
Comparative study of the estimation of exocrine pancreatic function using p-(N-acetyl-L-tyrosyl)- and p-(N-benzoyl-L-tyrosyl)aminobenzoic acid.
Pancreatitis
Degradation and inactivation of plasma tumor necrosis factor-alpha by pancreatic proteases in experimental acute pancreatitis.
Pancreatitis
Differences in time course of hepatocyte and pancreocyte damage after incubation with trypsin, chymotrypsin and 2.4-dinitrophenol.
Pancreatitis
Evidence of intracellular activation of serine proteases in acute cerulein-induced pancreatitis in rats.
Pancreatitis
Exocrine pancreatic function (serum immunoreactive trypsin, fecal chymotrypsin, and pancreatic isoamylase) in Indian diabetics.
Pancreatitis
Human acute pancreatitis: its pathogenesis in the light of immunocytochemical and ultrastructural findings in acinar cells.
Pancreatitis
Inhibition of human pancreatic proteinases by human plasma alpha2-antiplasmin and antithrombin.
Pancreatitis
Involvement of heparin cofactor II in chymotrypsin neutralization and in the pancreatic proteinase-antiproteinase interaction during acute pancreatitis in man.
Pancreatitis
Loss of chymotrypsin-like protease (CTRL) alters intrapancreatic protease activation but not pancreatitis severity in mice.
Pancreatitis
Raf-1 Kinase Inhibitory Protein (RKIP)-mediates Ethanol-induced Sensitization of Secretagogue Signaling in Pancreatic Acinar Cells.
Pancreatitis
Soybean trypsin inhibitor and cerulein accelerate recovery of cerulein-induced pancreatitis in rats.
Pancreatitis
The role of nitric oxide in caerulein-induced acute pancreatitis and the recovery process after inflammatory damage.
Pancreatitis
[Significance of immunoreactive lipase in the diagnosis of pancreatic diseases]
Pancreatitis
[Therapeutic effects of human urinary trypsin inhibitor on acute experimental pancreatitis]
Pancreatitis, Acute Necrotizing
Acute hemorrhagic pancreatic necrosis in mice. Intraparenchymal activation of zymogens, and other enzyme changes in pancreas and serum.
Pancreatitis, Alcoholic
[Fecal elastase-1 determination in the diagnosis of chronic pancreatitis]
Pancreatitis, Chronic
A preliminary report on urinary BT-PABA/PAS excretion index, serum pancreatic isoamylase and faecal chymotrypsin tests of pancreatic dysfunction in Sowetan Africans.
Pancreatitis, Chronic
A single-specimen fecal chymotrypsin test in the diagnosis of pancreatic insufficiency: correlation with secretin-cholecystokinin and NBT-PABA tests.
Pancreatitis, Chronic
Adequate enzymatic substitution in treating exocrine pancreatic insufficiency.
Pancreatitis, Chronic
Assessment of exocrine pancreatic dysfunction in chronic pancreatitis.
Pancreatitis, Chronic
Clinical evaluation of the faecal elastase test in the diagnosis and staging of chronic pancreatitis.
Pancreatitis, Chronic
Comparative study of the estimation of exocrine pancreatic function using p-(N-acetyl-L-tyrosyl)- and p-(N-benzoyl-L-tyrosyl)aminobenzoic acid.
Pancreatitis, Chronic
Diagnosis of chronic pancreatitis using noninvasive tests of exocrine pancreatic function--comparison to duodenal intubation tests.
Pancreatitis, Chronic
Diagnostic value of the fecal chymotrypsin test in pancreatic insufficiency, particularly chronic pancreatitis: correlation with the pancreozymin-secretin test, fecal fat excretion and final clinical diagnosis.
Pancreatitis, Chronic
Duodenal secretion and fecal excretion of pancreatic elastase-1 in healthy humans and patients with chronic pancreatitis.
Pancreatitis, Chronic
Evaluation of the secretin-cholecystokinin test for chronic pancreatitis by discriminant analysis.
Pancreatitis, Chronic
Faecal chymotrypsin assay in tropical and alcoholic chronic pancreatitis.
Pancreatitis, Chronic
Limitations of faecal chymotrypsin as a screening test for chronic pancreatitis.
Pancreatitis, Chronic
Oral administration of chymotrypsin labile peptide for a new test of exocrine pancreatic function (PET) in comparison and pancreozymin-secretin test.
Pancreatitis, Chronic
Relationship between PABA and Lundh tests: lack of influence of duodenal pH in vivo.
Pancreatitis, Chronic
The fecal chymotrypsin photometric assay in the evaluation of exocrine pancreatic capacity. Comparison with other direct and indirect pancreatic function tests.
Pancreatitis, Chronic
The usefulness of serum PABA measurement after BT-PABA administration in the diagnosis of chronic pancreatitis.
Pancreatitis, Chronic
Use of caerulein with submaximal doses of secretin as a test of pancreatic function in man.
Pancreatitis, Chronic
[Chymotrypsin activity and vitamin D and calcium metabolism in chronic pancreatitis]
Pancreatitis, Chronic
[Chymotrypsin activity in the stool: comparison of a new photometric technic and the standard titrimetric method]
Pancreatitis, Chronic
[Comparative study between the Lundh test and fecal chymotrypsin in chronic pancreatitis]
Pancreatitis, Chronic
[Comparison of three indirect pancreatic function tests in severe chronic pancreatitis--personal observations]
Pancreatitis, Chronic
[Determining chymotrypsin level in stools in the diagnosis of chronic pancreatitis]
Pancreatitis, Chronic
[Excretory pancreatic function: comparison of indirect function tests with the secretin-cholecystokinin test]
Pancreatitis, Chronic
[Fecal elastase-1 determination in the diagnosis of chronic pancreatitis]
Pancreatitis, Chronic
[Modified ALTAB test in the diagnosis of exocrine pancreatic insufficiency]
Pancreatitis, Chronic
[PABA test versus chymotrypsin and fat determinations in the stool in pancreatic functional diagnosis]
Parotitis
Chymotrypsin with sialendoscopy-assisted surgery for the treatment of chronic obstructive parotitis.
Pelvic Inflammatory Disease
[Association of essential oils of turpentine and chymotrypsin in the therapy of adnexitis.]
Penile Induration
[The action of ultrasonics on Peyronie's disease, accelerated by alpha-chymotrypsin.]
Penile Induration
[The action of ultrssonics in La Peyronie's disease accelerated with alpha-chymotrypsin.]
Periarthritis
[alpha-Chymotrypsin (quimotrase) in the therapy of periarthritis of the shoulder.]
Periarthritis
[Local alpha-chymotrypsin as selective therapy of scapulohumeral periarthritis.]
Periarthritis
[New studies of therapy of scapulo-humeral periarthritis with alpha chymotrypsin.]
Periarthritis
[Therapy of periarthritis of the shoulder- and elbow joints with hydrocortisone and chymotrypsin]
Periarthritis
[Treatment of scapulo-humeral periarthritis with alpha-chymotrypsin and rehabilitation]
Periodontal Pocket
Inhibitory effect of serum globulins on the adhesion of Prevotella nigrescens to hydroxyapatite.
Periodontitis
Salivary collagenase. Origin, characteristics and relationship to periodontal health.
Peripheral Vascular Diseases
Clinical studies on the use of parenteral trypsin and chymotrypsin in peripheral vascular disease.
Persistent Infection
Reovirus variants selected during persistent infections of L cells contain mutations in the viral S1 and S4 genes and are altered in viral disassembly.
Phlebitis
[The treatment of sprains and superficial phlebitis with a pommade of synthesized heparinoid base and alpha-chymotrypsin. Personal experience over 2 years with 85 patients]
Plasmacytoma
Evidence for a functional receptor for cyclosporin A on the surface of lymphocytes.
Pleural Effusion
The use of chymotrypsin as an adjuvant therapy in the treatment of tubercular pleural effusion.
Pleural Effusion
[Association of trypsin and chymotrypsin in pleural effusions of diverse etiology]
Pneumonia
[Use of chymotrypsin in complex therapy of chronic pneumonia and its effect on pharmacokinetics of penicillin]
Polyneuropathies
In vitro degradation of amyloid material by four proteases in tissue of a patient with familial amyloidotic polyneuropathy.
Pre-Eclampsia
Chymotrypsin Enhances Soluble Fms-Like Tyrosine Kinase 1 Production Through Protease-Activated Receptor 2 in Placenta-Derived Immortalized Human Trophoblast Cells.
Pre-Eclampsia
Endothelial angiotensin II generation induced by placenta-derived factors from preeclampsia.
Pre-Eclampsia
Protease chymotrypsin mediates the endothelial expression of P- and E-selectin, but not ICAM and VCAM, induced by placental trophoblasts from pre-eclamptic pregnancies.
Proctocolitis
[Tryptic enzymes in the differential diagnosis of inflammatory diseases of the colon (author's transl)]
Protein Deficiency
Exocrine pancreatic function in protein-deficient patas monkeys studied by means of a test meal and an indirect pancreatic function test.
Protein-Energy Malnutrition
[Comparative study of the effects of 2 types of protein-energy malnutrition followed by a balanced realimentation on trypsin and chymotrypsin activity of the pancreas and the pancreatic juice of the rat]
Proteinuria
Antimicrobial gentamicin activity in the presence of exogenous protease inhibitor (Bowman-Birk inhibitor) in gentamicin-induced nephrotoxicity in rats.
Psoriasis
Decreased specific anti-elastase activity in the uninvolved skin of patients with psoriasis.
Psychomotor Agitation
Toxicity to the pea aphid Acyrthosiphon pisum of anti-chymotrypsin isoforms and fragments of Bowman-Birk protease inhibitors from pea seeds.
Pulmonary Alveolar Proteinosis
Pulmonary alveolar proteinosis. Remission after therapy with trypsin and chymotrypsin.
Pulmonary Disease, Chronic Obstructive
A study on the possible role of chymotrypsin in the aetiology of equine chronic obstructive pulmonary disease (COPD).
Pulmonary Disease, Chronic Obstructive
Characterizing the Dynamics and Ligand-Specific Interactions in the Human Leukocyte Elastase through Molecular Dynamics Simulations.
Pulmonary Emphysema
[Trypsin plus chymotrypsin in chronic bronchitic forms with pulmonary emphysema.]
Pulpitis
The effect of a proteolytic enzyem mixture (Orenzyme-Forte) on experimentally induced pulpitis.
Pyoderma
Chymar ointment. A preliminary report of its use in pyodermas and other dermatoses.
Respiratory Hypersensitivity
A study on the possible role of chymotrypsin in the aetiology of equine chronic obstructive pulmonary disease (COPD).
Retinal Detachment
[Retinal detachment in aphakic eye following cataract extraction with use of chymotrypsin]
Retinoblastoma
Identification of discrete structural domains in the retinoblastoma protein. Amino-terminal domain is required for its oligomerization.
Sarcoma, Avian
Analysis of the catalytic domain of phosphotransferase activity of two avian sarcoma virus-transforming proteins.
Sarcoma, Experimental
The effect of administration of crystalline chymotrypsin upon placental transplants, spontaneous tumors and Jensen sarcoma in rats.
Severe Acute Respiratory Syndrome
Dissection study on the severe acute respiratory syndrome 3C-like protease reveals the critical role of the extra domain in dimerization of the enzyme: defining the extra domain as a new target for design of highly specific protease inhibitors.
Severe Acute Respiratory Syndrome
Identification of 22 N-glycosites on spike glycoprotein of SARS-CoV-2 and accessible surface glycopeptide motifs: implications for vaccination and antibody therapeutics.
Shock, Septic
Exocrine pancreatic function in critically ill patients: septic shock versus non-septic patients.
Sinusitis
[An experience in the use of alpha-chymotrypsin in treatment of paranasal sinusitis]
Sinusitis
[EXPERIENCES WITH THE USE OF ALPHA-CHYMOTRYPSIN NEBULIZER IN THE TREATMENT OF MULTIPLE SINUSITIS.]
Skin Diseases
Chymar ointment. A preliminary report of its use in pyodermas and other dermatoses.
Skin Diseases
Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition.
Staphylococcal Infections
Effect of hydrocortisone and chymotrypsin in experimental staphylococcal infections in rabbits.
Staphylococcal Infections
[Action of lincomycin, chymotrypsin and their combinations on the course of experimental staphylococcal infection]
Staphylococcal Infections
[Aspects of the therapeutic action of proteolytic enzymes and antibiotics in experimental staphylococcal infection. The effect of lincomycin, chymotrypsin and their combinations on leukocyte phagocytic activity]
Staphylococcal Infections
[Effect of chlorophyllypt and chymotrypsin on the course of experimental staphylococcal infection]
Staphylococcal Infections
[Effect of lincomycin, chymotrypsin and their combinations on the splenic plasmacytic reaction and the antibody titer in experimental staphylococcal infection]
Staphylococcal Infections
[Therapeutic action of proteolytic enzymes and antibiotics in experimental staphylococcal infection. The effect of lincomycin, chymotrypsin and their combinations on the level of autoplaque-forming cells in the blood and the immune adherence reaction of staphylococci]
Starvation
Effect of whey proteins, their oligopeptide hydrolysates and free amino acid mixtures on growth and nitrogen retention in fed and starved rats.
Starvation
Structural refinement of insecticidal plant proteinase inhibitors from Nicotiana alata.
Starvation
The effect of feeding on the secretion of pepsin, trypsin and chymotrypsin in the Atlantic salmon,Salmo salar L.
Steatorrhea
Comparative diagnostic accuracy of four tubeless pancreatic function tests in chronic pancreatitis.
Steatorrhea
Effect of whey proteins, their oligopeptide hydrolysates and free amino acid mixtures on growth and nitrogen retention in fed and starved rats.
Steatorrhea
Exocrine pancreatic function in children with progressive familial intrahepatic cholestasis type 2.
Steatorrhea
Pancreolauryl test. Evaluation of a tubeless pancreatic function test in comparison with other indirect and direct tests for exocrine pancreatic function.
Steatorrhea
Secondary impairment of pancreatic function as a cause of severe malabsorption in intestinal giardiasis: a case report.
Steatorrhea
[Echostructure of the pancreas. Comparison with exocrine secretory activity of the pancreas in patients with diabetes mellitus]
Steatorrhea
[Evaluation of exocrine pancreatic function by the haptocorrin degradation test of the duodenal fluid collected by endoscopy]
Steatorrhea
[The significance of the evocative test in the diagnosis of chronic pancreatitis (author's transl)]
Stomach Neoplasms
A simplified technique using chymotrypsin lavage for the cytological diagnosis of gastric cancer.
Stomach Neoplasms
Point, minute and small cancers of the stomach at the early developmental stage detected by improved chymotrypsin lavage method for diagnostic cytology.
Stomach Neoplasms
The cytologic diagnosis of gastric cancer of chymotrypsin lavage. II. The detection of early malignancy.
Stomach Neoplasms
The prevalence of pancreatic acinar differentiation in gastric adenocarcinoma: report of a case and immunohistochemical study of 111 additional cases.
Stomach Neoplasms
[Cytodiagnosis of gastric cancer. Evaluation of results obtained by washing the stomach with chymotrypsin and physiologic saline solutions]
Stomach Neoplasms
[Cytological study of alpha-chymotrypsin stomach washing in diagnosis of stomach neoplasms - analysis of 600 cases]
Strabismus
Use of intramuscular chymotrypsin in controlling tissue reaction following strabismus surgery. A preliminary study.
Subarachnoid Hemorrhage
[Use of alpha-chymotrypsin in the treatment of subarachnoid hemorrhage]
Swine Vesicular Disease
[Studies on the increase of weights of lymphatic glands, of lymph and peritoneal fluid and their contents of chymotrypsin and virus in pigs suffering hog cholera (author's transl)]
Syphilis
[Effect of different doses of the novocaine salt of benzylpenicillin and its combination with chymotrypsin on the penicillin content of the blood serum in syphilis patients]
Syphilis
[The efficacy of using chymotrypsin in the combined treatment of syphilis patients]
Thrombasthenia
Aggregation of chymotrypsin-treated thrombasthenic platelets is mediated by fibrinogen binding to glycoproteins IIb and IIIa.
Thrombophlebitis
[Intramuscular administration of combined trypsin and chymotrypsin in therapy of thrombophlebitis of obstetric and gynecological origin.]
Thrombosis
Non-isotopic method for quantitation of platelets and erythrocytes in experimental thrombi.
Tuberculosis
Antigenic epitopes on Mycobacterium tuberculosis recognized by antibodies in tuberculosis and mouse antisera.
Tuberculosis
Isolation of tuberculin peptides from tuberculin purified protein derivative (PPD).
Tuberculosis
[The use of chymotrypsin by parenteral route in chemio-antibiotic combinations in the treatment of primary lymph nodal tuberculosis of childhood.]
Tuberculosis, Pulmonary
[The use of chymopsin and chymotrypsin in antibacterial therapy and surgical treatment of patients with pulmonary tuberculosis]
Tumor Virus Infections
INDUCTION OF TUMORS IN DOMESTIC RABBITS WITH NUCLEIC ACID PREPARATIONS FROM PARTIALLY PURIFIED SHOPE PAPILLOMA VIRUS AND FROM EXTRACTS OF THE PAPILLOMAS OF DOMESTIC AND COTTONTAIL RABBITS.
Urinary Bladder Neoplasms
Specific sequences of fibronectin activate the protein kinase C signal transduction pathway in invasive bladder cancer.
Urinary Tract Infections
[The treatment of urinary tract infection following transurethral prostatic resection by use of alpha-chymotrypsin enteric-coated tablet]
Uterine Cervical Neoplasms
Characterization of the anti-cancer-cell parasporal proteins of a Bacillus thuringiensis isolate.
Uterine Cervical Neoplasms
Purification and identification of novel cytotoxic oligopeptides from soft coral Sarcophyton glaucum.
Vaccinia
Mechanism of inhibition of vaccinia DNA topoisomerase by novobiocin and coumermycin.
Vaccinia
THE LS-ANTIGEN OF VACCINIA : IV. CHEMICAL ANALYSIS OF LS AND THE EFFECT OF CHYMOTRYPSIN ON LS.
Waldenstrom Macroglobulinemia
Primary structure of human J chain: isolation and characterization of tryptic and chymotryptic peptides of human J chain.
Whooping Cough
Dissociation of catalytic and invasive activities of Bordetella pertussis adenylate cyclase.
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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
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ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SOURCE
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
additional information
SDS-PAGE of partial purified chymotrypsin results in the resolution of bands of 31 and 29 kDa, in addition to others with masses lower than 14 kDa
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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Lopes, A.R.; Sato, P.M.; Terra, W.R.
Insect chymotrypsins: chloromethyl ketone inactivation and substrate specificity relative to possible coevolutional adaptation of insects and plants
Arch. Insect Biochem. Physiol.
70
188-203
2009
Bos taurus, Tenebrio molitor, Diatraea saccharalis, Periplaneta americana (Q1M0X9), Spodoptera frugiperda (Q86M89), Spodoptera frugiperda
brenda
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Release 2023.1 (January 2023)
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