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The expected taxonomic range for this enzyme is: Rattus norvegicus
Synonyms
alpha-glucose 1-phosphate phosphodiesterase, more
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alpha-glucose 1-phosphate phosphodiesterase
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6-(D-glucose-1-phospho)-D-mannosylglycoprotein + H2O = alpha-D-glucose 1-phosphate + D-mannosylglycoprotein
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hydrolysis of phosphoric diester
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6-(D-glucose-1-phospho)-D-mannosylglycoprotein glucose-1-phosphohydrolase
The enzyme is specific for the product of EC 2.7.8.19 UDP-glucose---glycoprotein glucose phosphotransferase.
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6-(D-glucose-1-phospho)-D-mannosylglycoprotein + H2O
D-glucose alpha-1-phosphate + D-mannosylglycoprotein
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Substrates: enzyme is unable to remove alpha-glucose-1-phosphate from UDPglucose or glycosylphosphoryldolichol
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6-(D-glucose-1-phospho)-D-mannosylglycoprotein + H2O
D-glucose alpha-1-phosphate + D-mannosylglycoprotein
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6-(D-glucose-1-phospho)-D-mannosylglycoprotein + H2O
D-glucose alpha-1-phosphate + D-mannosylglycoprotein
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Substrates: important in the regulation of secretion, reaction accompanying regulated secretory release
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6-(D-glucose-1-phospho)-D-mannosylglycoprotein + H2O
D-glucose alpha-1-phosphate + D-mannosylglycoprotein
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Substrates: important in the regulation of secretion, reaction accompanying regulated secretory release
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PO43-
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phosphate is able to even partially slow the degradation
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not effectively inhibited by castanospermine, 1-deoxynojirimycin, bromoconduritol, tartrate, fluoride, molybdate or beta-glycerophosphate
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2 - 3.2
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isoelectric focusing
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rat, Sprague-Dawley
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brenda
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brenda
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brenda
Highest Expressing Human Cell Lines
Cell Line Links
Gene Links
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Srisomsap, C.; Richardson, K.L.; Jay, J.C.; Marchase, R.B.
An alpha-glucose-1-phosphate phosphodiesterase is present in rat liver cytosol
J. Biol. Chem.
264
20540-20546
1989
Rattus norvegicus
brenda
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