Disease on EC 2.8.2.9 - tyrosine-ester sulfotransferase and Organism(s) Homo sapiens and UniProt Accession P50226
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Acute Kidney Injury
Hepatic sulfotransferase as a nephropreventing target by suppression of the uremic toxin indoxyl sulfate accumulation in ischemic acute kidney injury.
Acute Kidney Injury
Suppressed Hepatic Production of Indoxyl Sulfate Attenuates Cisplatin-Induced Acute Kidney Injury in Sulfotransferase 1a1-Deficient Mice.
Adenocarcinoma
Analysis of A4gnt Knockout Mice Reveals an Essential Role for Gastric Sulfomucins in Preventing Gastritis Cystica Profunda.
Adenocarcinoma
Association of elevated sulfatides and sulfotransferase activities with human renal cell carcinoma.
Adenocarcinoma
Cloning and expression of cDNA encoding human placental estrogen sulfotransferase.
Adenocarcinoma
Human uterine endometrial adenocarcinoma: characteristic acquirement of synthetic potentials for II3SO3-LacCer and ganglio series sulfoglycosphingolipids after transfer of the cancer cells to culture.
Adenocarcinoma
O-glycan biosynthesis in human colorectal adenoma cells during progression to cancer.
Adenocarcinoma, Mucinous
Specificities of N-acetylglucosamine-6-O-sulfotransferases in relation to L-selectin ligand synthesis and tumor-associated enzyme expression.
Alopecia
Characterization of follicular minoxidil sulfotransferase activity in a cohort of pattern hair loss patients from the Indian Subcontinent.
Alopecia
Doppler laser imaging predicts response to topical minoxidil in the treatment of female pattern hair loss.
Alopecia
Microneedling improves minoxidil response in androgenetic alopecia patients by upregulating follicular sulfotransferase enzymes.
Alopecia
Novel topical booster enhances follicular sulfotransferase activity in patients with androgenetic alopecia: a new strategy to improve minoxidil response.
Alopecia
Oral minoxidil bio-activation by hair follicle outer root sheath cell sulfotransferase enzymes predicts clinical efficacy in female pattern hair loss.
Alopecia
Sulfotransferase activity in plucked hair follicles predicts response to topical minoxidil in the treatment of female androgenetic alopecia.
Alopecia
Sulfotransferase activity in plucked hair follicles predicts response to topical minoxidil treatment in Brazilian female pattern hair loss patients.
Alopecia
The effect of topical minoxidil treatment on follicular sulfotransferase enzymatic activity.
Alopecia
Tretinoin enhances minoxidil response in androgenetic alopecia patients by upregulating follicular sulfotransferase enzymes.
Alzheimer Disease
Reduced sulfotransferase SULT2A1 activity in patients with Alzheimer's disease.
Arthritis, Rheumatoid
A HEV-restricted sulfotransferase is expressed in rheumatoid arthritis synovium and is induced by lymphotoxin-alpha/beta and TNF-alpha in cultured endothelial cells.
Brain Diseases
Molecular analysis of carbohydrate N-acetylgalactosamine 4-O sulfotransferase 8 (CHST8) as a candidate gene for bovine spongiform encephalopathy susceptibility.
Breast Neoplasms
Association between SULT1A1 Arg213His (rs9282861) Polymorphism and Risk of Breast Cancer: A Systematic Review and Meta-Analysis.
Breast Neoplasms
Association of sulfotransferase SULT1A1 with breast cancer risk: a meta-analysis of case-control studies with subgroups of ethnic and menopausal statue.
Breast Neoplasms
Biological responses of progestogen metabolites in normal and cancerous human breast.
Breast Neoplasms
Biotransformation of melatonin in human breast cancer cell lines: role of sulfotransferase 1A1.
Breast Neoplasms
Chondroitin sulfates play a major role in breast cancer metastasis: a role for CSPG4 and CHST11 gene expression in forming surface P-selectin ligands in aggressive breast cancer cells.
Breast Neoplasms
Control of sulfatase and sulfotransferase activities by medrogestone in the hormone-dependent MCF-7 and T-47D human breast cancer cell lines.
Breast Neoplasms
Correlation of estrogen sulfotransferase activity and proliferation in normal and carcinomatous human breast. A hypothesis.
Breast Neoplasms
CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment.
Breast Neoplasms
Differential expression pattern of estrogen receptors, aromatase, and sulfotransferase in breast cancer tissue and corresponding lymph node metastases.
Breast Neoplasms
Effect of nomegestrol acetate on estrogen biosynthesis and transformation in MCF-7 and T47-D breast cancer cells.
Breast Neoplasms
Effect of nomegestrol acetate on human estrogen sulfotransferase activity in the hormone-dependent MCF-7 and T-47D breast cancer cell lines.
Breast Neoplasms
Estradiol-17beta sulfotransferase activity in canine osteosarcoma D17 cells.
Breast Neoplasms
Estrone sulfatase versus estrone sulfotransferase in human breast cancer: potential clinical applications.
Breast Neoplasms
Expression of aromatase and estrogen sulfotransferase in preinvasive and invasive breast cancer.
Breast Neoplasms
Expression of sulfotransferase isoform 1A1 (SULT1A1) in breast cancer cells significantly increases 4-hydroxytamoxifen-induced apoptosis.
Breast Neoplasms
Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer.
Breast Neoplasms
Human estrogen sulfotransferase (hEST1) activities and its mRNA in various breast cancer cell lines. Effect of the progestin, promegestone (R-5020).
Breast Neoplasms
Intratumoural mRNA expression of genes from the oestradiol metabolic pathway and clinical and histopathological parameters of breast cancer.
Breast Neoplasms
New developments in intracrinology of human breast cancer: estrogen sulfatase and sulfotransferase.
Breast Neoplasms
Phenol sulfotransferases: hormonal regulation, polymorphism, and age of onset of breast cancer.
Breast Neoplasms
Recent insight on the control of enzymes involved in estrogen formation and transformation in human breast cancer.
Breast Neoplasms
Resveratrol modulates human mammary epithelial cell O-acetyltransferase, sulfotransferase, and kinase activation of the heterocyclic amine carcinogen N-hydroxy-PhIP.
Breast Neoplasms
Selective spatial upregulation of intratumoral stromal aromatase in breast cancer patients: evidence for imbalance of local estrogen metabolism.
Breast Neoplasms
Sex-specific expression mechanism of hepatic estrogen inactivating enzyme and transporters in diabetic women.
Breast Neoplasms
Sulfation through the looking glass--recent advances in sulfotransferase research for the curious.
Breast Neoplasms
The metabolism and analysis of isoflavones and other dietary polyphenols in foods and biological systems.
Breast Neoplasms
UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients.
Carcinogenesis
2-Acetylaminofluorene-mediated alteration in the level of liver arylsulfotransferase IV during rat hepatocarcinogenesis.
Carcinogenesis
Aryl sulfotransferase IV deficiency in rat liver carcinogenesis initiated with diethylnitrosamine and promoted with N-2-fluorenylacetamide or its C-9-oxidized metabolites.
Carcinogenesis
Detection and Quantification of Specific DNA Adducts by Liquid Chromatography-Tandem Mass Spectrometry in the Livers of Rats Given Estragole at the Carcinogenic Dose.
Carcinogenesis
Hypomethylation of the rat aryl sulfotransferase IV gene and amplification of a DNA sequence during multistage 2-acetylaminofluorene hepatocarcinogenesis.
Carcinogenesis
N-hydroxy-2-acetylaminofluorene sulfotransferase: its probable role in carcinogenesis and in protein-(methion-S-yl) binding in rat liver.
Carcinogenesis
SULT1E1 inhibits cell proliferation and invasion by activating PPAR? in breast cancer.
Carcinogenesis
The natural basil flavonoid nevadensin protects against a methyleugenol-induced marker of hepatocarcinogenicity in male F344 rat.
Carcinoma
Arsenic methylation capability, myeloperoxidase and sulfotransferase genetic polymorphisms, and the stage and grade of urothelial carcinoma.
Carcinoma
Association of elevated sulfatides and sulfotransferase activities with human renal cell carcinoma.
Carcinoma
Cancer-associated expression of glycolipid sulfotransferase gene in human renal cell carcinoma cells.
Carcinoma
Elevated serum level of glycolipid sulfotransferase in patients with hepatocellular carcinoma.
Carcinoma
Hepatocyte growth factor elevates the activity levels of glycolipid sulfotransferases in renal cell carcinoma cells.
Carcinoma
Human uterine endometrial adenocarcinoma: characteristic acquirement of synthetic potentials for II3SO3-LacCer and ganglio series sulfoglycosphingolipids after transfer of the cancer cells to culture.
Carcinoma
Inhibitory effects of sulfation inhibitors on initiation of pancreatic ductal carcinogenesis by N-nitrosobis(2-oxopropyl)amine in hamsters.
Carcinoma
Potential tumor markers for human gastric cancer: an elevation of glycan:sulfotransferases and a concomitant loss of alpha1,2-fucosyltransferase activities.
Carcinoma
Quantitative analysis of the association between sulfotransferase isoform 1A1 polymorphism and risk of urothelial carcinoma.
Carcinoma
[Characterization of glycolipid sulfotransferase fractionated from rat kidney and involvement of the enzyme in human cancer]
Carcinoma, Hepatocellular
2-Acetylaminofluorene-mediated alteration in the level of liver arylsulfotransferase IV during rat hepatocarcinogenesis.
Carcinoma, Hepatocellular
Basil extract inhibits the sulfotransferase mediated formation of DNA adducts of the procarcinogen 1'-hydroxyestragole by rat and human liver S9 homogenates and in HepG2 human hepatoma cells.
Carcinoma, Hepatocellular
Characterization of a complementary DNA for rat liver aryl sulfotransferase IV and use in evaluating the hepatic gene transcript levels of rats at various stages of 2-acetylaminofluorene-induced hepatocarcinogenesis.
Carcinoma, Hepatocellular
Development and application of test methods for the detection of dietary constituents which protect against heterocyclic aromatic amines.
Carcinoma, Hepatocellular
Development of a competitive reverse-transcription polymerase chain reaction for quantitative measurement of sulfotransferase subfamily 1A enzyme in human hepatoma cells.
Carcinoma, Hepatocellular
Dopamine-induced SULT1A3/4 promotes EMT and cancer stemness in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Down-regulation of dehydroepiandrosterone sulfotransferase gene in human hepatocellular carcinoma.
Carcinoma, Hepatocellular
Hypomethylation of the rat aryl sulfotransferase IV gene and amplification of a DNA sequence during multistage 2-acetylaminofluorene hepatocarcinogenesis.
Carcinoma, Hepatocellular
Inconsistent expression of glycolipid sulfotransferase activity between hepatoma and serum.
Carcinoma, Hepatocellular
Investigation of the genotoxic effects of 2-amino-9H-pyrido[2,3-b]indole in different organs of rodents and in human derived cells.
Carcinoma, Hepatocellular
LC-MS/MS quantification of sulfotransferases is better than conventional immunogenic methods in determining human liver SULT activities: implication in precision medicine.
Carcinoma, Hepatocellular
[Characterization of glycolipid sulfotransferase fractionated from rat kidney and involvement of the enzyme in human cancer]
Carcinoma, Intraductal, Noninfiltrating
Expression of aromatase and estrogen sulfotransferase in preinvasive and invasive breast cancer.
Carcinoma, Intraductal, Noninfiltrating
Intracrinology of sex steroids in ductal carcinoma in situ (DCIS) of human breast: comparison to invasive ductal carcinoma (IDC) and non-neoplastic breast.
Carcinoma, Renal Cell
Association of elevated sulfatides and sulfotransferase activities with human renal cell carcinoma.
Carcinoma, Renal Cell
Cancer-associated expression of glycolipid sulfotransferase gene in human renal cell carcinoma cells.
Carcinoma, Renal Cell
Elevated serum level of glycolipid sulfotransferase in patients with hepatocellular carcinoma.
Carcinoma, Renal Cell
Hepatocyte growth factor elevates the activity levels of glycolipid sulfotransferases in renal cell carcinoma cells.
Carcinoma, Renal Cell
Sulfolipids and glycolipid sulfotransferase activities in human renal cell carcinoma cells.
Carcinoma, Renal Cell
[Characterization of glycolipid sulfotransferase fractionated from rat kidney and involvement of the enzyme in human cancer]
Carcinoma, Squamous Cell
Human uterine endometrial adenocarcinoma: characteristic acquirement of synthetic potentials for II3SO3-LacCer and ganglio series sulfoglycosphingolipids after transfer of the cancer cells to culture.
Cardiovascular Diseases
Metabolism, Protein Binding, and Renal Clearance of Microbiota-Derived p-Cresol in Patients with CKD.
Cerebral Infarction
Effect of the combination of astragaloside IV and Panax notoginseng saponins on pyroptosis and necroptosis in rat models of cerebral ischemia-reperfusion.
Chondrosarcoma
Epigenetics: methylation-associated repression of heparan sulfate 3-O-sulfotransferase gene expression contributes to the invasive phenotype of H-EMC-SS chondrosarcoma cells.
Choriocarcinoma
Human uterine endometrial adenocarcinoma: characteristic acquirement of synthetic potentials for II3SO3-LacCer and ganglio series sulfoglycosphingolipids after transfer of the cancer cells to culture.
Colonic Neoplasms
Metabolic differences and their impact on human disease Sulfotransferase and colorectal cancer.
Colorectal Neoplasms
A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer.
Colorectal Neoplasms
Metabolic differences and their impact on human disease Sulfotransferase and colorectal cancer.
Colorectal Neoplasms
[A case-control study on the association between the genetic polymorphism of sulfotransferase 1A1, diet and susceptibility of colorectal cancer]
Congenital Abnormalities
Regulation of expression of the rodent cytosolic sulfotransferases.
Corneal Dystrophies, Hereditary
Measurement of activities of human serum sulfotransferases which transfer sulfate to the galactose residues of keratan sulfate and to the nonreducing end N-acetylglucosamine residues of N-acetyllactosamine trisaccharide: comparison between normal controls and patients with macular corneal dystrophy.
Corneal Dystrophies, Hereditary
Serum sulfotransferase levels in patients with macular corneal dystrophy type I.
COVID-19
Relationships between hyperinsulinaemia, magnesium, vitamin D, thrombosis and COVID-19: rationale for clinical management.
Cystic Fibrosis
Regulation of hepatic sulfotransferase (SULT) 1E1 expression and effects on estrogenic activity in cystic fibrosis (CF).
Cystic Fibrosis
Repression of CFTR activity in human MMNK-1 cholangiocytes induces sulfotransferase 1E1 expression in co-cultured HepG2 hepatocytes.
Dehydration
Crystallization of retinol dehydratase from Spodoptera frugiperda: improvement of crystal quality by modification by ethylmercurythiosalicylate.
Encephalopathy, Bovine Spongiform
Molecular analysis of carbohydrate N-acetylgalactosamine 4-O sulfotransferase 8 (CHST8) as a candidate gene for bovine spongiform encephalopathy susceptibility.
Endometrial Neoplasms
Aberrant pre-receptor regulation of estrogen and progesterone action in endometrial cancer.
Endometrial Neoplasms
Effective Selection of a Well-Differentiated Type of Human Uterine Endometrial Carcinoma Cells by Transfection of the Sulfotransferase Gene and Possible Association of Sulfoglycolipids With Well-Differentiated Phenotypes.
Endometrial Neoplasms
Estrogen productivity of endometrium and endometrial cancer tissue; influence of aromatase on proliferation of endometrial cancer cells.
Endometrial Neoplasms
Expression analysis of estrogen-metabolizing enzymes in human endometrial cancer.
Endometrial Neoplasms
SULT1E1 inhibits cell proliferation and invasion by activating PPAR? in breast cancer.
Eosinophilia
Astragaloside IV attenuates allergic inflammation by regulation Th1/Th2 cytokine and enhancement CD4(+)CD25(+)Foxp3 T cells in ovalbumin-induced asthma.
Erectile Dysfunction
Sulfation of apomorphine by human sulfotransferases: evidence of a major role for the polymorphic phenol sulfotransferase, SULT1A1.
Exanthema
12-OH-nevirapine sulfate, formed in the skin, is responsible for nevirapine-induced skin rash.
Fatty Liver
Astragaloside IV inhibits protein tyrosine phosphatase 1B and improves insulin resistance in insulin-resistant HepG2 cells and triglyceride accumulation in oleic acid (OA)-treated HepG2 cells.
Glioma
Effects of methyl mercury and triethyllead on Na+K+ATPase and pyruvate dehydrogenase activities in glioma C6 cells.
Herpes Simplex
Biosynthesis of 3-O-sulfated heparan sulfate: unique substrate specificity of heparan sulfate 3-O-sulfotransferase isoform 5.
Herpes Simplex
Structural analysis of the sulfotransferase (3-o-sulfotransferase isoform 3) involved in the biosynthesis of an entry receptor for herpes simplex virus 1.
Herpes Simplex
Sulfotransferase and Heparanase: Remodeling Engines in Promoting Virus Infection and Disease Development.
Herpes Simplex
Zebrafish 3-O-Sulfotransferase-4 Generated Heparan Sulfate Mediates HSV-1 Entry and Spread.
Huntington Disease
Acetaminophen sulfation in patients with Parkinson's disease or Huntington's disease is not impaired.
Hyperthyroidism
Serum concentration of androstenediol and androstenediol sulfate in patients with hyperthyroidism and hypothyroidism.
Infections
Glycosylation-related gene expression profiling in brain and spleen of scrapie-affected mouse.
Infections
Molecular cloning of a sulfotransferase in Arabidopsis thaliana and regulation during development and in response to infection with pathogenic bacteria.
Insulin Resistance
Astragaloside IV inhibits protein tyrosine phosphatase 1B and improves insulin resistance in insulin-resistant HepG2 cells and triglyceride accumulation in oleic acid (OA)-treated HepG2 cells.
Intellectual Disability
Platelet abnormalities in aggressive subjects with mental deficiency.
Ischemic Stroke
Epistasis analysis for estrogen metabolic and signaling pathway genes on young ischemic stroke patients.
Joint Dislocations
Further delineation of CANT1 phenotypic spectrum and demonstration of its role in proteoglycan synthesis.
Kidney Neoplasms
Cancer-associated alternative usage of multiple promoters of human GalCer sulfotransferase gene.
Kidney Neoplasms
Purification and characterization of 3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase from human renal cancer cells.
Kidney Neoplasms
Pyridoxal 5'-phosphate binds to a lysine residue in the adenosine 3'-phosphate 5'-phosphosulfate recognition site of glycolipid sulfotransferase from human renal cancer cells.
Kidney Neoplasms
Regulation of activity levels of glycolipid sulfotransferases by transforming growth factor alpha in renal cell carcinoma cells.
Kidney Neoplasms
[Studies on the regulation of glycolipid sulfotransferase activity in human renal cancer cells]
Leukemia
Changes in heparan sulfate sulfotransferases and cell-surface heparan sulfate during SKM-1 cells granulocytic differentiation and A549 cells epithelial-mesenchymal transition.
Leukemia
Principal drug-metabolizing enzyme systems in L1210 leukemia sensitive or resistant to BCNU in vivo.
Leukemia, Lymphocytic, Chronic, B-Cell
Deregulation of the carbohydrate (chondroitin 4) sulfotransferase 11 (CHST11) gene in a B-cell chronic lymphocytic leukemia with a t(12;14)(q23;q32).
Liver Cirrhosis
Elevated serum level of glycolipid sulfotransferase in patients with hepatocellular carcinoma.
Liver Diseases
Altered UDP-glucuronosyltransferase and sulfotransferase expression and function during progressive stages of human nonalcoholic fatty liver disease.
Liver Diseases
Astragaloside IV inhibits protein tyrosine phosphatase 1B and improves insulin resistance in insulin-resistant HepG2 cells and triglyceride accumulation in oleic acid (OA)-treated HepG2 cells.
Liver Diseases
Downregulation of sulfotransferase expression and activity in diseased human livers.
Liver Neoplasms
2-Acetylaminofluorene-mediated alteration in the level of liver arylsulfotransferase IV during rat hepatocarcinogenesis.
Liver Neoplasms
Reaction product inactivation of aryl sulfotransferase IV following electrophilic substitution by the sulfuric acid ester of N-hydroxy-2-acetylaminofluorene.
Lung Neoplasms
Changes in heparan sulfate sulfotransferases and cell-surface heparan sulfate during SKM-1 cells granulocytic differentiation and A549 cells epithelial-mesenchymal transition.
Lung Neoplasms
Sulfotransferase (SULT) 1A1 polymorphism as a predisposition factor for lung cancer: a case-control analysis.
Lymphatic Metastasis
Differential expression pattern of estrogen receptors, aromatase, and sulfotransferase in breast cancer tissue and corresponding lymph node metastases.
Mastocytoma
Functional analysis of conserved cysteines in heparan sulfate N-deacetylase-N-sulfotransferases.
Melanoma
Human Natural Killer-1 Sulfotransferase (HNK-1ST)-induced Sulfate Transfer Regulates Laminin-binding Glycans on ?-Dystroglycan.
Melanoma
Human uterine endometrial adenocarcinoma: characteristic acquirement of synthetic potentials for II3SO3-LacCer and ganglio series sulfoglycosphingolipids after transfer of the cancer cells to culture.
Melanoma
Melanoma Cell Adhesion and Migration Is Modulated by the Uronyl 2-O Sulfotransferase.
Myocardial Infarction
HIF-1? signaling activation by post-ischemia treatment with astragaloside IV attenuates myocardial ischemia-reperfusion injury.
Neoplasm Metastasis
Differential expression pattern of estrogen receptors, aromatase, and sulfotransferase in breast cancer tissue and corresponding lymph node metastases.
Neoplasm Metastasis
Mechanism of regulation and suppression of melanoma invasiveness by novel retinoic acid receptor-gamma target gene carbohydrate sulfotransferase 10.
Neoplasms
2-Acetylaminofluorene-mediated alteration in the level of liver arylsulfotransferase IV during rat hepatocarcinogenesis.
Neoplasms
Aryl sulfotransferase IV deficiency in rat liver carcinogenesis initiated with diethylnitrosamine and promoted with N-2-fluorenylacetamide or its C-9-oxidized metabolites.
Neoplasms
Changes in heparan sulfate sulfotransferases and cell-surface heparan sulfate during SKM-1 cells granulocytic differentiation and A549 cells epithelial-mesenchymal transition.
Neoplasms
Characterization of a complementary DNA for rat liver aryl sulfotransferase IV and use in evaluating the hepatic gene transcript levels of rats at various stages of 2-acetylaminofluorene-induced hepatocarcinogenesis.
Neoplasms
Comparison of mouse and human colon tumors with regard to phase I and phase II drug-metabolizing enzyme systems.
Neoplasms
Cytochrome P450 (CYP) 1A2, sulfotransferase (SULT) 1A1, and N-acetyltransferase (NAT) 2 polymorphisms and susceptibility to urothelial cancer.
Neoplasms
Dehydroepiandrosterone sulfotransferase as a possible shunt for the control of steroid metabolism in human mammary carcinoma.
Neoplasms
Differential expression pattern of estrogen receptors, aromatase, and sulfotransferase in breast cancer tissue and corresponding lymph node metastases.
Neoplasms
Discovery of Carbohydrate Sulfotransferase Inhibitors from a Kinase-Directed Library We thank Sharon Long and Dave Keating for providing both the NodH sulfotransferase and APS Kinase during our preliminary experiments and Jack Kirsch for numerous helpful conversations. J.I.A. and K.G.B were supported by NIH Molecular Biophysics Training Grant (No. T32GM0895). This research was funded by grants to C.R.B. from the Pew Scholars Program, the W. M. Keck Foundation and the American Cancer Society (Grant No. RPG9700501BE).
Neoplasms
Effects of partial hepatectomy and dietary phenobarbital on liver and mammary tumorigenesis by two N-hydroxy-N-acylaminobiphenyls in female CD rats.
Neoplasms
Estrogen-metabolizing gene polymorphisms in the assessment of female hormone-dependent cancer risk.
Neoplasms
Expanding the view of breast cancer metabolism: Promising molecular targets and therapeutic opportunities.
Neoplasms
Expression of aromatase and estrogen sulfotransferase in preinvasive and invasive breast cancer.
Neoplasms
Expression of sulfotransferase SULT1A1 in cancer cells predicts susceptibility to the novel anticancer agent NSC-743380.
Neoplasms
Feminization as a result of both peripheral conversion of androgens and direct estrogen production from an adrenocortical carcinoma.
Neoplasms
Human uterine endometrial adenocarcinoma: characteristic acquirement of synthetic potentials for II3SO3-LacCer and ganglio series sulfoglycosphingolipids after transfer of the cancer cells to culture.
Neoplasms
Inflammatory cues modulate the expression of secretory product genes, Golgi sulfotransferases and sulfomucin production in LS174T cells.
Neoplasms
Inhibition by pentachlorophenol of the initiating and promoting activities of 1'-hydroxysafrole for the formation of enzyme-altered foci and tumors in rat liver.
Neoplasms
Malabaricone C-containing mace extract inhibits safrole bioactivation and DNA adduct formation both in vitro and in vivo.
Neoplasms
Paclitaxel inhibits N-acetyltransferase activity and gene expression in human stomach tumor cells (SC-M1).
Neoplasms
Phylogenomic approaches to common problems encountered in the analysis of low copy repeats: the sulfotransferase 1A gene family example.
Neoplasms
Polymorphisms in hormone metabolism and growth factor genes and mammographic density in Norwegian postmenopausal hormone therapy users and non-users.
Neoplasms
Principal xenobiotic-metabolizing enzyme systems in human head and neck squamous cell carcinoma.
Neoplasms
Species differences of glucuronidation and sulfation in relation to hepatocarcinogenesis.
Neoplasms
Strong evidence from studies with brachymorphic mice and pentachlorophenol that 1'-sulfoöxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1'-hydroxysafrole in mouse liver.
Neoplasms
Structure of a human carcinogen-converting enzyme, SULT1A1. Structural and kinetic implications of substrate inhibition.
Neoplasms
Sulfolipids and glycolipid sulfotransferase activities in human renal cell carcinoma cells.
Neoplasms
Sulfotransferase SULT1A1 Arg213His polymorphism with cancer risk: a meta-analysis of 53 case-control studies.
Neoplasms
Tandem mass spectrometry analysis of N2-(trans-Isoestragol-3'-yl)-2'-deoxyguanosine as a strategy to study species differences in sulfotransferase conversion of the proximate carcinogen 1'-hydroxyestragole.
Neoplasms
The pattern of glycosyl- and sulfotransferase activities in cancer cell lines: a predictor of individual cancer-associated distinct carbohydrate structures for the structural identification of signature glycans.
Neoplasms
UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients.
Neoplasms
[Characterization of glycolipid sulfotransferase fractionated from rat kidney and involvement of the enzyme in human cancer]
Neuralgia
Regulation of the KATP-JNK gap junction signaling pathway by immunomodulator astragaloside IV attenuates neuropathic pain.
Neuroblastoma
Proteomic study of amyloid beta (25-35) peptide exposure to neuronal cells: Impact on APE1/Ref-1's protein-protein interaction.
Neurodegenerative Diseases
Sulfotransferase 1A3/4 copy number variation is associated with neurodegenerative disease.
Neuronal Ceroid-Lipofuscinoses
Chromosome 16 microdeletion in a patient with juvenile neuronal ceroid lipofuscinosis (Batten disease).
Non-alcoholic Fatty Liver Disease
Altered UDP-glucuronosyltransferase and sulfotransferase expression and function during progressive stages of human nonalcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Astragaloside IV inhibits protein tyrosine phosphatase 1B and improves insulin resistance in insulin-resistant HepG2 cells and triglyceride accumulation in oleic acid (OA)-treated HepG2 cells.
Obesity
Drug-metabolizing enzyme and transporter expression in a mouse model of diabetes and obesity.
Osteochondrodysplasias
Further delineation of CANT1 phenotypic spectrum and demonstration of its role in proteoglycan synthesis.
Osteochondrodysplasias
Spondyloepiphyseal dysplasia, chondroitin sulfate type: a possible defect of PAPS--chondroitin sulfate sulfotransferase in humans.
Parkinson Disease
Acetaminophen sulfation in patients with Parkinson's disease or Huntington's disease is not impaired.
Parkinson Disease
Sulfation of apomorphine by human sulfotransferases: evidence of a major role for the polymorphic phenol sulfotransferase, SULT1A1.
Pheochromocytoma
Proteomic study of amyloid beta (25-35) peptide exposure to neuronal cells: Impact on APE1/Ref-1's protein-protein interaction.
Phyllodes Tumor
Selective spatial upregulation of intratumoral stromal aromatase in breast cancer patients: evidence for imbalance of local estrogen metabolism.
Polycystic Kidney Diseases
Decreased sulfotransferase SULT1C2 gene expression in DPT-induced polycystic kidney.
Polycystic Ovary Syndrome
Effect of insulin and testosterone on androgen production and transcription of SULT2A1 in the NCI-h295r adrenocortical cell line.
Prostatic Neoplasms
Inhibitory Interplay of SULT2B1b Sulfotransferase with AKR1C3 Aldo-keto Reductase in Prostate Cancer.
Prostatic Neoplasms
SULT2B1b sulfotransferase: induction by vitamin D receptor and reduced expression in prostate cancer.
Prostatic Neoplasms
TNF? enhances the motility and invasiveness of prostatic cancer cells by stimulating the expression of selective glycosyl- and sulfotransferase genes involved in the synthesis of selectin ligands.
Pulmonary Disease, Chronic Obstructive
Increased levels of enzymes involved in local estradiol synthesis in chronic obstructive pulmonary disease.
Rhinitis, Allergic
miR-487b mitigates allergic rhinitis through inhibition of the IL-33/ST2 signaling pathway.
Sarcoma
Human uterine endometrial adenocarcinoma: characteristic acquirement of synthetic potentials for II3SO3-LacCer and ganglio series sulfoglycosphingolipids after transfer of the cancer cells to culture.
Sarcoma
Potential tumor markers for human gastric cancer: an elevation of glycan:sulfotransferases and a concomitant loss of alpha1,2-fucosyltransferase activities.
Sepsis
Astragaloside IV attenuates inflammatory reaction via activating immune function of regulatory T-cells inhibited by HMGB1 in mice.
Spinal Cord Injuries
The Adhesion Molecule-Characteristic HNK-1 Carbohydrate Contributes to Functional Recovery After Spinal Cord Injury in Adult Zebrafish.
Starvation
[Effect of starvation and acetone on the enzyme systems of biotransformation and toxicity of xenobiotics--CYP2E1 substrates in rats]
Thymoma
Sulfated syndecan 1 is critical to preventing cellular senescence by modulating fibroblast growth factor receptor endocytosis.
Tuberculosis
Molecular cloning and expression of a novel glycolipid sulfotransferase in Mycobacterium tuberculosis.
Tuberculosis
Overproduction, purification and preliminary X-ray diffraction analysis of a sulfotransferase from Mycobacterium tuberculosis H37Rv.
tyrosine-ester sulfotransferase deficiency
Aryl sulfotransferase IV deficiency in rat liver carcinogenesis initiated with diethylnitrosamine and promoted with N-2-fluorenylacetamide or its C-9-oxidized metabolites.
tyrosine-ester sulfotransferase deficiency
Upregulation of UGT2B4 Expression by 3'-Phosphoadenosine-5'-Phosphosulfate Synthase Knockdown: Implications for Coordinated Control of Bile Acid Conjugation.
Urinary Bladder Neoplasms
Polymorphisms for aromatic amine metabolism in humans: relevance for human carcinogenesis.
Virus Diseases
Sulfotransferase and Heparanase: Remodeling Engines in Promoting Virus Infection and Disease Development.
Wilms Tumor
[Characterization of glycolipid sulfotransferase fractionated from rat kidney and involvement of the enzyme in human cancer]