show all | hide all No of entries

Information on EC 2.7.4.3 - adenylate kinase and Organism(s) Arabidopsis thaliana and UniProt Accession O82514

for references in articles please use BRENDA:EC2.7.4.3
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
Inorganic triphosphate can also act as donor.
Specify your search results
Select one or more organisms in this record:
This record set is specific for:
Arabidopsis thaliana
UNIPROT: O82514
Word Map
The taxonomic range for the selected organisms is: Arabidopsis thaliana
The enzyme appears in selected viruses and cellular organisms
Synonyms
phosphotransferase, myokinase, adenylate kinase 1, nonstructural protein 4b, cinap, adenylate kinase 2, adenylokinase, atp:amp phosphotransferase, structural maintenance of chromosome protein, adenylate kinase 5, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
5'-AMP-kinase
-
-
-
-
adenylate kinase 6
302
-
adenylic kinase
-
-
-
-
adenylokinase
-
-
-
-
kinase, adenylate (phosphorylating)
-
-
-
-
kinase, myo- (phosphorylating)
-
-
-
-
myokinase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phospho group transfer
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
ATP:AMP phosphotransferase
Inorganic triphosphate can also act as donor.
CAS REGISTRY NUMBER
COMMENTARY hide
9013-02-9
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + AMP
ADP + ADP
show the reaction diagram
-
ATP is the preferred phosphate donor and AMP is the best phosphate acceptor
-
-
?
additional information
?
-
interaction between mitochondrial adenylate kinase and nucleoside diphosphate kinase. Adenylate kinase stimulates nucleoside diphosphate kinase activity, whereas nucleoside diphosphate kinase inhibits adenylate kinase activity. the net effect may be unchanged ADP production albeit with different rates of substrate consumption
-
-
-
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
additional information
?
-
O82514
interaction between mitochondrial adenylate kinase and nucleoside diphosphate kinase. Adenylate kinase stimulates nucleoside diphosphate kinase activity, whereas nucleoside diphosphate kinase inhibits adenylate kinase activity. the net effect may be unchanged ADP production albeit with different rates of substrate consumption
-
-
-
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Mg2+
-
required for activity
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
isoform AK1
UniProt
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
most highly expressed isoform AK1
Manually annotated by BRENDA team
isoforms AMK3 and AMK4
Manually annotated by BRENDA team
additional information
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
-
the absence of denylate kinase 6 reduces stem elongation but does not delay development
physiological function
-
adenylate kinase 6 is an essential stem growth factor in Arabidopsis
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
Sequence
KAD4_ARATH
246
0
26932
Swiss-Prot
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
22600
-
x * 22600, calculated from amino acid sequence
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
?
-
x * 22600, calculated from amino acid sequence; x * 27000-28000, SDS-PAGE
additional information
interaction between mitochondrial adenylate kinase and nucleoside diphosphate kinase. Adenylate kinase stimulates nucleoside diphosphate kinase activity, whereas nucleoside diphosphate kinase inhibits adenylate kinase activity. The net effect may be unchanged ADP production albeit with different rates of substrate consumption
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
PURIFICATION/commentary
ORGANISM
UNIPROT
LITERATURE
Ni-affinity column chromatography and Superdex-75 gel filtration
-
CLONED/commentary
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli
expressed in Escherichia coli BL21(DE3) cells
-
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Lange, P.R.; Geserick, C.; Tischendorf, G.; Zrenner, R.
Functions of chloroplastic adenylate kinases in Arabidopsis
Plant Physiol.
146
492-504
2008
Arabidopsis thaliana, Arabidopsis thaliana (Q8VYL1), Arabidopsis thaliana (Q9FIJ7)
Manually annotated by BRENDA team
Johansson, M.; Hammargren, J.; Uppsaell, E.; MacKenzie, A.; Knorpp, C.
The activities of nucleoside diphosphate kinase and adenylate kinase are influenced by their interaction
Plant Sci.
174
192-199
2008
Arabidopsis thaliana (O82514)
Manually annotated by BRENDA team
Feng, X.; Yang, R.; Zheng, X.; Zhang, F.
Identification of a novel nuclear-localized adenylate kinase 6 from Arabidopsis thaliana as an essential stem growth factor
Plant Physiol. Biochem.
61
180-186
2012
Arabidopsis thaliana
Manually annotated by BRENDA team
Select items on the left to see more content.