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Information on EC 2.5.1.23 - sym-norspermidine synthase

for references in articles please use BRENDA:EC2.5.1.23

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IUBMB Comments

The enzyme has been originally characterized from the protist Euglena gracilis [1,2]. The enzyme from the archaeon Sulfolobus solfataricus can transfer the propylamine moiety from S-adenosyl 3-(methylsulfanyl)propylamine to putrescine, sym-norspermidine and spermidine with lower efficiency . cf. EC 2.5.1.16 (spermidine synthase) and EC 2.5.1.22 (spermine synthase).

The expected taxonomic range for this enzyme is: Eukaryota, Archaea

Synonyms
HbSpe 1, propylaminc transferase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl 3-(methylsulfanyl)propylamine + propane-1,3-diamine = S-methyl-5'-thioadenosine + bis(3-aminopropyl)amine
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
long-chain polyamine biosynthesis
Highest Expressing Human Cell Lines
Cell Line Links Gene Links