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Information on EC 2.5.1.18 - glutathione transferase

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EC Tree
IUBMB Comments
A group of enzymes of broad specificity. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. Also catalyses the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange.
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This record set is specific for:
UNIPROT: Q2YFE3
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Reaction Schemes
Synonyms
gst, glutathione s-transferase, gstm1, gstp1, gstt1, glutathione-s-transferase, glutathione transferase, gsta1, gst pi, gstm3, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
glutathione S-transferase
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glutathione S-alkyl transferase
-
-
-
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glutathione S-aralkyltransferase
-
-
-
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glutathione S-aryltransferase
-
-
-
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glutathione S-transferase
-
-
-
-
glutathione S-transferase X
-
-
-
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GSH S-transferase
-
-
-
-
GSHTase-P
-
-
-
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S-(hydroxyalkyl)glutathione lyase
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
aryl group transfer
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-
-
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SYSTEMATIC NAME
IUBMB Comments
RX:glutathione R-transferase
A group of enzymes of broad specificity. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. Also catalyses the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange.
CAS REGISTRY NUMBER
COMMENTARY hide
50812-37-8
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
delta class GST; housedust mite, delta class GST isozyme
SwissProt
Manually annotated by BRENDA team
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
Q2YFE3_DERPT
228
0
26652
TrEMBL
-
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
orf Dp7018E11, DNA and amino acid sequence determination and analysis, phylogenetic analysis
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Dougall, A.; Holt, D.C.; Fischer, K.; Currie, B.J.; Kemp, D.J.; Walton, S.F.
Identification and characterization of Sarcoptes scabiei and Dermatophagoides pteronyssinus glutathione S-transferases: implication as a potential major allergen in crusted scabies
Am. J. Trop. Med. Hyg.
73
977-984
2005
Dermatophagoides pteronyssinus (P46419), Dermatophagoides pteronyssinus (Q2YFE3), Dermatophagoides pteronyssinus (Q2YFE4), Dermatophagoides pteronyssinus (Q2YFE5), Dermatophagoides pteronyssinus, Sarcoptes scabiei (Q2YFE6), Sarcoptes scabiei (Q2YFE7), Sarcoptes scabiei (Q2YFE8), Sarcoptes scabiei (Q2YFE9), Sarcoptes scabiei (Q5ISV1), Sarcoptes scabiei (Q8I9R9), Sarcoptes scabiei
Manually annotated by BRENDA team