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Information on EC 2.4.99.4 - beta-galactoside alpha-2,3-sialyltransferase

for references in articles please use BRENDA:EC2.4.99.4
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IUBMB Comments
The acceptor is Galbeta1,3GalNAc-R, where R is H, a threonine or serine residue in a glycoprotein, or a glycolipid. Lactose can also act as acceptor. May be identical with EC 2.4.99.2 monosialoganglioside sialyltransferase.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
alpha 2,3-ST , alpha-2,3-sialyltransferase, alpha2-->3 sialyltransferase, alpha2-3-sialyltransferase 1, alpha3-SA-T, alpha3SA-T, beta-D-Gal-(1-3)-D-GalNAc alpha-(2-3)-sialyltransferase, beta-D-galactoside alpha2->3 sialyltransferase, beta-galactoside a-2,3-sialyltransferase, beta-galactoside alpha-2,3-sialyltransferase , more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
CMP-N-acetylneuraminate + beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R = CMP + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R
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