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The enzyme recognizes the sequence beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl (known as type 1 histo-blood group precursor disaccharide) in non-reducing termini of glycan moieties in glycoproteins and glycolipids . When acting on gangloside GM1a, it forms gangloside GD1a .
alpha(2,3)-sialyltransferase IV, alpha(2,3)sialyltransferase, alpha(2,3)sialyltransferases, alpha-2,3-sialyltransferase IV, alpha2,3(N) sialyltransferase, alpha2,3(N)ST, alpha2,3(O) sialyltransferase, alpha2,3(O)ST, alpha2,3-ST, CMP-N-acetylneuraminate:D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-(1<->1)-ceramide N-acetylneuraminyltransferase, more