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Information on EC 2.4.1.50 - procollagen galactosyltransferase and Organism(s) Mus musculus and UniProt Accession Q8K297

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EC Tree
     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.50 procollagen galactosyltransferase
IUBMB Comments
Involved in the synthesis of carbohydrate units in the complement system (cf. EC 2.4.1.66 procollagen glucosyltransferase).
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This record set is specific for:
Mus musculus
UNIPROT: Q8K297
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Word Map
The taxonomic range for the selected organisms is: Mus musculus
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
glt25d1, b3galt6, colgalt2, glt25d2, collagen galactosyltransferase, colgalt1, galactosyltransferase ii, hydroxylysyl galactosyltransferase, beta3galt6, collagen beta(1-o)galactosyltransferase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
collagen galactosyltransferase
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collagen hydroxylysyl galactosyltransferase
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-
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collagen hydroxylysyl glycosylsyltransferase
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galactosyltransferase, uridine diphosphogalactose-collagen
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hydroxylysine galactosyltransferase
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lysyl hydroxylase 3
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UDP galactose-collagen galactosyltransferase
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UDPgalactose:5-hydroxylysine-collagen galactosyltransferase
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uridine diphosphogalactose-collagen galactosyltransferase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hexosyl group transfer
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
UDP-galactose:procollagen-5-hydroxy-L-lysine D-galactosyltransferase
Involved in the synthesis of carbohydrate units in the complement system (cf. EC 2.4.1.66 procollagen glucosyltransferase).
CAS REGISTRY NUMBER
COMMENTARY hide
9028-07-3
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
UniProt
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
mice fed a standard chow or high-fat diet for 5 weeks show significantly decreased level of GLT25D1 which coincides with a decrease in high-molecular-weight adiponectin
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
GT251_MOUSE
617
0
71061
Swiss-Prot
Secretory Pathway (Reliability: 1)
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Risteli, M.; Ruotsalainen, H.; Salo, A.M.; Sormunen, R.; Sipilae, L.; Baker, N.L.; Lamande, S.R.; Vimpari-Kauppinen, L.; Myllylae, R.
Reduction of lysyl hydroxylase 3 causes deleterious changes in the deposition and organization of extracellular matrix
J. Biol. Chem.
284
28204-28211
2009
Homo sapiens (O60568), Mus musculus
Manually annotated by BRENDA team
Webster, J.A.; Yang, Z.; Kim, Y.H.; Loo, D.; Mosa, R.M.; Li, H.; Chen, C.
Collagen beta (1-O) galactosyltransferase 1 (GLT25D1) is required for the secretion of high molecular weight adiponectin and affects lipid accumulation
Biosci. Rep.
37
BSR20170105
2017
Homo sapiens (Q8NBJ5), Homo sapiens, Mus musculus (Q8K297)
Manually annotated by BRENDA team