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Disease on EC 2.4.1.281 - 4-O-beta-D-mannosyl-D-glucose phosphorylase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
4-o-beta-d-mannosyl-d-glucose phosphorylase deficiency
The CGRP receptor component RAMP1 links sensory innervation with YAP activity in the regenerating liver.
Adenocarcinoma of Lung
Abnormal gene expression and gene fusion in lung adenocarcinoma with high-throughput RNA sequencing.
Adenomyosis
Possible involvement of neuropeptide and neurotransmitter receptors in Adenomyosis.
Asthma
Deficiency of RAMP1 attenuates antigen-induced airway hyperresponsiveness in mice.
Expression of functional receptor activity modifying protein 1 by airway epithelial cells with dysregulation in asthma.
Brain Ischemia
Pathophysiological roles of adrenomedullin-RAMP2 system in acute and chronic cerebral ischemia.
Carcinogenesis
RAMP1 Is a Direct NKX3.1 Target Gene Up-Regulated in Prostate Cancer that Promotes Tumorigenesis.
Carcinoma
Role of receptor activity modifying protein 1 in function of the calcium sensing receptor in the human TT thyroid carcinoma cell line.
Carcinoma, Hepatocellular
Receptor Activity-Modifying Protein 2 (RAMP2) alters glucagon receptor trafficking in hepatocytes with functional effects on receptor signalling.
Cardiomegaly
Cardiac adrenomedullin: its role in cardiac hypertrophy and heart failure.
Cardiomyopathies
Changes of adrenomedullin and receptor activity modifying protein 2 (RAMP2) in myocardium and aorta in rats with isoproterenol-induced myocardial ischemia.
Cardiovascular Diseases
Changes of adrenomedullin and receptor activity modifying protein 2 (RAMP2) in myocardium and aorta in rats with isoproterenol-induced myocardial ischemia.
Endothelial Restoration of Receptor Activity-Modifying Protein 2 Is Sufficient to Rescue Lethality, but Survivors Develop Dilated Cardiomyopathy.
Regulation of adrenomedullin and its family peptide by RAMP system--lessons from genetically engineered mice.
Unaltered mRNA expression of calcitonin-like receptor and receptor activity modifying proteins in human arteries in stroke and myocardial infarction.
Cerebral Infarction
Haplotype-based case-control study of receptor (calcitonin) activity-modifying protein-1 gene in cerebral infarction.
Colitis
RAMP1 suppresses mucosal injury from dextran sodium sulfate-induced colitis in mice.
COVID-19
Circulating Levels of Calcitonin Gene-Related Peptide Are Lower in COVID-19 Patients.
Diabetes Mellitus, Type 1
The role of adrenomedullin and receptors in glomerular hyperfiltration in streptozotocin-induced diabetic rats.
Endometriosis
Inhibition of receptor activity-modifying protein 1 suppresses the development of endometriosis and the formation of blood and lymphatic vessels.
Essential Hypertension
Haplotype-based, case-control study of the receptor (calcitonin) activity-modifying protein (RAMP) 1 gene in essential hypertension.
Fetal Death
Research resource: Haploinsufficiency of receptor activity-modifying protein-2 (RAMP2) causes reduced fertility, hyperprolactinemia, skeletal abnormalities, and endocrine dysfunction in mice.
Fetal Growth Retardation
Research resource: Haploinsufficiency of receptor activity-modifying protein-2 (RAMP2) causes reduced fertility, hyperprolactinemia, skeletal abnormalities, and endocrine dysfunction in mice.
Glaucoma, Open-Angle
Mutant RAMP2 causes primary open-angle glaucoma via the CRLR-cAMP axis.
Glomerulonephritis
Adrenomedullin (AM) and receptor-activity-modifying proteins in glomeruli with Thy.1 glomerulonephritis.
Heart Failure
Increased gene expression of adrenomedullin and adrenomedullin-receptor complexes, receptor-activity modifying protein (RAMP)2 and calcitonin-receptor-like receptor (CRLR) in the hearts of rats with congestive heart failure.
Increased myocardial expression of RAMP1 and RAMP3 in rats with chronic heart failure.
[Increased atria expression of receptor activity-modifying proteins in heart failure patients]
Hepatitis
RAMP1 in Kupffer cells is a critical regulator in immune-mediated hepatitis.
Hepatitis B, Chronic
Treated with interferon and the gene polymorphism of CGRP and its receptor.
Hyperalgesia
Expression of ASIC3 in the Trigeminal Nucleus Caudalis Plays a Role in a Rat Model of Recurrent Migraine.
Genetic enhancement of calcitonin gene-related Peptide-induced central sensitization to mechanical stimuli in mice.
Hypertension
Calcitonin gene-related peptide (CGRP) and its role in hypertension.
Haplotype-based case-control study of receptor (calcitonin) activity-modifying protein-1 gene in cerebral infarction.
Receptor activity-modifying protein 1 increases baroreflex sensitivity and attenuates Angiotensin-induced hypertension.
Hypertension, Pulmonary
[Changes of intermedin/adrenomedullin 2 and its receptors in the right ventricle of rats with chronic hypoxic pulmonary hypertension.]
Infertility
Receptor activity-modifying proteins 2 and 3 have distinct physiological functions from embryogenesis to old age.
Liver Cirrhosis
Cirrhosis decreases vasoconstrictor response to electrical field stimulation in rat mesenteric artery: role of calcitonin gene-related peptide.
The gene expression of adrenomedullin, calcitonin-receptor-like receptor and receptor activity modifying proteins (RAMPs) in CCl4-induced rat liver cirrhosis.
Lung Neoplasms
Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation.
Lymphedema
RAMP1 signaling improves lymphedema and promotes lymphangiogenesis in mice.
Migraine Disorders
Aberrant DNA methylation pattern may enhance susceptibility to migraine: A novel perspective.
Association study of the calcitonin gene-related polypeptide-alpha (CALCA) and the receptor activity modifying 1 (RAMP1) genes with migraine.
CGRP Signaling via CALCRL Increases Chemotherapy Resistance and Stem Cell Properties in Acute Myeloid Leukemia.
DNA methylation of RAMP1 gene in migraine: an exploratory analysis.
Immunohistochemical localization of the calcitonin gene-related peptide binding site in the primate trigeminovascular system using functional antagonist antibodies.
Ramping it up: RAMP1 and the implications for migraine.
Role of calcitonin gene-related peptide in light-aversive behavior: implications for migraine.
Sensitization of calcitonin gene-related peptide receptors by receptor activity-modifying protein-1 in the trigeminal ganglion.
Neoplasm Metastasis
Deficiency of the adrenomedullin-RAMP3 system suppresses metastasis through the modification of cancer-associated fibroblasts.
Expression of adrenomedullin in human colorectal tumors and its role in cell growth and invasion in vitro and in xenograft growth in vivo.
The endothelial adrenomedullin-RAMP2 system regulates vascular integrity and suppresses tumour metastasis.
Neoplasms
Adrenomedullin 2 attenuates LPS-induced inflammation in microglia cells by receptor-mediated cAMP-PKA pathway.
Adrenomedullin blockade suppresses growth of human hormone independent prostate tumor xenograft in mice.
Deficiency of the adrenomedullin-RAMP3 system suppresses metastasis through the modification of cancer-associated fibroblasts.
Expression of adrenomedullin 2/intermedin in human adrenal tumors and attached non-neoplastic adrenal tissues.
Expression of adrenomedullin in human colorectal tumors and its role in cell growth and invasion in vitro and in xenograft growth in vivo.
Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation.
Neuropeptide-induced modulation of carcinogenesis in a metastatic breast cancer cell line (MDA-MB-231LUC+).
RAMP1 Is a Direct NKX3.1 Target Gene Up-Regulated in Prostate Cancer that Promotes Tumorigenesis.
The endothelial adrenomedullin-RAMP2 system regulates vascular integrity and suppresses tumour metastasis.
Neuroblastoma
Differential expression of adrenomedullin and its receptor component, receptor activity modifying protein (RAMP) 2 during hypoxia in cultured human neuroblastoma cells.
Interaction of receptor-activity-modifying protein1 with tubulin.
Pancreatic Neoplasms
Adrenomedullin is induced by hypoxia and enhances pancreatic cancer cell invasion.
Adrenomedullin promotes the growth of pancreatic ductal adenocarcinoma through recruitment of myelomonocytic cells.
Pancreatitis
The neuropeptide receptor subunit RAMP1 constrains the innate immune response during acute pancreatitis in mice.
Periodontitis
Gene expression analysis of neuropeptides in oral mucosa during periodontal disease in non-human primates.
Peritonitis
Deficiency of the CGRP receptor component RAMP1 attenuates immunosuppression during the early phase of septic peritonitis.
Pheochromocytoma
Expression and effect of adrenomedullin in pheochromocytoma.
Photophobia
Role of calcitonin gene-related peptide in light-aversive behavior: implications for migraine.
Pre-Eclampsia
Evidence for decreased calcitonin gene-related peptide (CGRP) receptors and compromised responsiveness to CGRP of fetoplacental vessels in preeclamptic pregnancies.
Placental gene expression of calcitonin gene-related peptide and nitric oxide synthases in preeclampsia: effects of magnesium sulfate.
Prostatic Neoplasms
Adrenomedullin blockade suppresses growth of human hormone independent prostate tumor xenograft in mice.
Novel biomarkers for prostate cancer including noncoding transcripts.
RAMP1 Is a Direct NKX3.1 Target Gene Up-Regulated in Prostate Cancer that Promotes Tumorigenesis.
Pulmonary Fibrosis
Regulation of myofibroblast differentiation and bleomycin-induced pulmonary fibrosis by adrenomedullin.
Sepsis
Decreased gene expression of adrenomedullin receptor in mouse lungs during sepsis.
Stroke
Genetic Variants of RAMP2 and CLR are Associated with Stroke.
Thyroid Neoplasms
Role of receptor activity modifying protein 1 in function of the calcium sensing receptor in the human TT thyroid carcinoma cell line.
Ureteral Obstruction
Intermedin is upregulated and attenuates renal fibrosis by inhibition of oxidative stress in rats with unilateral ureteral obstruction.
Rat receptor-activity-modifying proteins (RAMPs) for adrenomedullin/CGRP receptor: cloning and upregulation in obstructive nephropathy.
Vascular Calcification
Alterations of adrenomedullin and its receptor system components in calcified vascular smooth muscle cells.
Vascular Diseases
Receptor activity-modifying protein-1 augments cerebrovascular responses to calcitonin gene-related peptide and inhibits angiotensin II-induced vascular dysfunction.
Wiskott-Aldrich Syndrome
Receptor Activity-Modifying Protein 2 (RAMP2) alters glucagon receptor trafficking in hepatocytes with functional effects on receptor signalling.