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Information on EC 2.4.1.162 - aldose beta-D-fructosyltransferase
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2.4.1.162 aldose beta-D-fructosyltransferaseSpecify your search results
Word Map
- 2.4.1.162
- fructans
- streptococcus
- mutans
- fructooligosaccharides
- 1-kestose
- inulin
-
prebiotic
- salivarius
-
transfructosylation
-
glucosyltransferases
- levans
- levansucrase
- lolium
-
sucrose:sucrose
- perenne
-
cariogenic
- nystose
-
sucrose:fructan
- 6g-fft
- inulosucrase
- invertases
- ryegrass
-
inulin-type
-
pectinex
-
sucrose-containing
- chicory
-
sucrose-dependent
- sobrinus
-
fructan:fructan
- beta-fructofuranosidase
The enzyme appears in viruses and cellular organisms
Reaction Schemes
Synonyms
fructosyltransferase, 
more
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
beta-fructofuranoside, acceptor (aldose) fructosyltransferase
beta-fructosyl transferase
fructosyltransferase
FTF
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REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
alpha-D-aldosyl1 beta-D-fructoside + D-aldose2 = D-aldose1 + alpha-D-aldosyl2 beta-D-fructoside
-
-
-
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
hexosyl group transfer
-
-
-
-
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SYSTEMATIC NAME
IUBMB Comments
alpha-D-aldosyl-beta-D-fructoside:aldose 1-beta-D-fructosyltransferase
-
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CAS REGISTRY NUMBER
COMMENTARY
9031-67-8
-
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
1',6'-dichlorosucrose + fructose acceptor
?
-
1',6'-dichlorosucrose has some donor activity
-
-
?
alpha-D-galactopyranosyl-(1->6)-O-alpha-D-glucopyranosyl-(1->2)-D-fructofuranoside + sucrose
alpha-D-galactopyranosyl-(1->6)-O-alpha-D-glucopyranoside + ?
D-glucose 6-benzoate + sucrose
sucrose 6-benzoate + D-glucose
-
-
-
?
D-sucrose + D-galactose 6-acetate
D-glucose + beta-D-fructofuranosyl-(2,1)-D-6-O-acetyl-galactopyranoside
-
-
-
-
?
D-sucrose + D-gluconic acid
D-glucose + beta-D-fructofuranosyl-(2,1)-D-gluconic acid
-
-
-
-
?
raffinose + D-xylose
beta-D-fructofuranosyl-2,1-alpha-D-xylopyranoside + alpha-D-galactopyranosyl alpha-D-glucopyranoside
-
-
-
-
?
raffinose + galactose
beta-D-fructofuranosyl-2,1-D-galactopyranoside + alpha-D-galactopyranosyl alpha-D-glucopyranoside
-
-
-
?
raffinose + xylose
beta-D-fructofuranosyl-2,1-alpha-D-xylopyranoside + alpha-D-galactopyranosyl alpha-D-glucopyranoside
-
-
-
?
sucrose + 3-O-methyl alpha-D-glucose
D-glucose + beta-D-fructofuranosyl-(2->1)-3-O-methyl-alpha-D-glucopyranoside
sucrose + 3-O-methyl-D-glucose
D-glucose + beta-D-fructofuranosyl-(2,1)-3-O-methyl-D-glucoside
-
-
-
-
?
sucrose + 3-O-methyl-D-glucose
D-glucose + beta-D-fructofuranosyl-(2->1)-3-O-methyl-D-glucopyranoside
sucrose + 4-chloro-4-deoxy-D-galactose
D-glucose + beta-D-fructofuranosyl-(2->1)-4-deoxy-4-chloro-D-galactopyranoside
sucrose + 4-chloro-4-deoxy-D-glucose 6-acetate
D-glucose + beta-D-fructofuranosyl-(2->1)-4-chloro-4-deoxy-D-glucopyranoside 6-acetate
sucrose + 6-chloro-6-deoxy-D-glucose
D-glucose + beta-D-fructofuranosyl-(2,1)-6-chloro-6-deoxy-D-glucoside
-
-
-
-
?
sucrose + 6-chloro-6-deoxy-D-glucose
D-glucose + beta-D-fructofuranosyl-(2->1)-6-chloro-6-deoxy-D-glucoside
sucrose + 6-O-benzyl-D-glucose
D-glucose + beta-D-fructofuranosyl-(2,1)-6-O-benzyl-D-glucoside
-
-
-
-
?
sucrose + 6-O-benzyl-D-glucose
D-glucose + beta-D-fructofuranosyl-(2->1)-6-O-benzyl-D-glucoside
sucrose + 6-O-methyl-D-galactose
D-glucose + beta-D-fructofuranosyl-(2,1)-6-O-methyl-D-galactoside
-
-
-
-
?
sucrose + 6-O-methyl-D-galactose
D-glucose + beta-D-fructofuranosyl-(2->1)-6-O-methyl-D-galactoside
sucrose + 6-O-methyl-D-glucose
D-glucose + beta-D-fructofuranosyl-(2,1)-6-O-methyl-D-glucoside
-
-
-
-
?
sucrose + 6-O-methyl-D-glucose
D-glucose + beta-D-fructofuranosyl-(2->1)--6-O-methyl-D-glucoside
sucrose + cellobiose
D-glucose + beta-D-fructofuranosyl-(2,1)-cellobioside
-
-
-
-
?
sucrose + D-arabinose
D-glucose + beta-D-fructofuranosyl-(2,1)-D-arabinoside
-
-
-
-
?
sucrose + D-fucose
D-glucose + beta-D-fructofuranosyl-(2,1)-D-fucoside
-
-
-
-
?
sucrose + D-galactose
beta-D-fructofuranosyl-2,1-D-galactopyranoside + D-glucose
-
-
-
?
sucrose + D-galactose
D-glucose + beta-D-fructofuranosyl-(2,1)-D-galactopyranoside
-
-
-
-
?
sucrose + D-galactose 6-acetate
D-glucose + beta-D-fructofuranosyl-(2->1)-D-6-O-acetyl-galactopyranoside
sucrose + D-glucose 6-acetate
D-glucose + beta-D-fructofuranosyl-(2->1)-6-O-acetyl-D-glucoside
sucrose + D-glucose 6-phosphate
D-glucose + beta-D-fructofuranosyl-(2->1)-D-glucopyranoside 6-phosphate
sucrose + D-lactose
D-glucose + beta-D-fructofuranosyl-(2,1)-D-lactoside
-
-
-
-
?
sucrose + D-lyxose
D-glucose + beta-D-fructofuranosyl-(2,1)-D-lyxoside
-
-
-
-
?
sucrose + D-maltose
D-glucose + beta-D-fructofuranosyl-(2,1)-D-maltoside
-
-
-
-
?
sucrose + D-mannose
D-glucose + beta-D-fructofuranosyl-(2,1)-D-mannopyranoside
-
-
-
-
?
sucrose + D-ribose
D-glucose + beta-D-fructofuranosyl-(2,1)-D-riboside
-
-
-
-
?
sucrose + D-xylose
D-glucose + beta-D-fructofuranosyl-(2,1)-alpha-D-xylopyranoside
-
-
-
-
?
sucrose + D-xylose
D-glucose + beta-D-fructofuranosyl-2,1-alpha-D-xylopyranoside
-
-
-
-
?
sucrose + isomaltose
D-glucose + beta-D-fructofuranosyl-(2,1)-isomaltoside
-
-
-
-
?
sucrose + L-arabinose
D-glucose + beta-D-fructofuranosyl-(2,1)-L-arabinoside
-
-
-
-
?
sucrose + L-rhamnose
D-glucose + beta-D-fructofuranosyl-(2,1)-L-rhamnoside
-
-
-
-
?
sucrose + maltohexaose
D-glucose + beta-D-fructofuranosyl-(2,1)-maltohexaoside
-
-
-
-
?
sucrose + maltopentaose
D-glucose + beta-D-fructofuranosyl-(2,1)-maltopentaoside
-
-
-
-
?
sucrose + maltotetraose
D-glucose + beta-D-fructofuranosyl-(2,1)-maltotetraoside
-
-
-
-
?
sucrose + melibiose
D-glucose + beta-D-fructofuranosyl-(2,1)-mellibioside
-
-
-
-
?
sucrose + xylose
beta-D-fructofuranosyl-2,1-alpha-D-xylopyranoside + D-glucose
-
-
-
?
6,1',6'-trichlorosucrose + fructose acceptor
?
-
6, 1',6'-trichlorosucrose has some donor activity
-
-
?
6,1',6'-trichlorosucrose + fructose acceptor
?
Bacillus subtilis NCIB 11871
-
6, 1',6'-trichlorosucrose has some donor activity
-
-
?
alpha-D-galactopyranosyl-(1->6)-O-alpha-D-glucopyranosyl-(1->2)-D-fructofuranoside + sucrose
alpha-D-galactopyranosyl-(1->6)-O-alpha-D-glucopyranoside + ?
-
-
-
-
?
alpha-D-galactopyranosyl-(1->6)-O-alpha-D-glucopyranosyl-(1->2)-D-fructofuranoside + sucrose
alpha-D-galactopyranosyl-(1->6)-O-alpha-D-glucopyranoside + ?
-
-
-
-
?
fructose donor + fructose acceptor
D-aldose + D-aldosyl beta-D-fructoside
-
-
the products can act as acceptors for further reactions, leading to oligosaccharides or polysaccharides
?
fructose donor + fructose acceptor
D-aldose + D-aldosyl beta-D-fructoside
-
the donor must be a beta-fructosyl ring attached to the anomeric carbon of an aldose by an 1, 2 link, acceptors can be monomeric or oligomeric hexoses or pentoses, no acceptors are inosital, 2-deoxyglucose, glucosamine
-
?
fructose donor + fructose acceptor
D-aldose + D-aldosyl beta-D-fructoside
-
-
the products can act as acceptors for further reactions, leading to oligosaccharides or polysaccharides
?
fructose donor + fructose acceptor
D-aldose + D-aldosyl beta-D-fructoside
-
the donor must be a beta-fructosyl ring attached to the anomeric carbon of an aldose by an 1, 2 link, acceptors can be monomeric or oligomeric hexoses or pentoses, no acceptors are inosital, 2-deoxyglucose, glucosamine
-
?
sucrose + 3-O-methyl alpha-D-glucose
D-glucose + beta-D-fructofuranosyl-(2->1)-3-O-methyl-alpha-D-glucopyranoside
-
-
-
-
?
sucrose + 3-O-methyl alpha-D-glucose
D-glucose + beta-D-fructofuranosyl-(2->1)-3-O-methyl-alpha-D-glucopyranoside
-
-
-
-
?
sucrose + 3-O-methyl-D-glucose
D-glucose + beta-D-fructofuranosyl-(2->1)-3-O-methyl-D-glucopyranoside
-
-
-
-
?
sucrose + 3-O-methyl-D-glucose
D-glucose + beta-D-fructofuranosyl-(2->1)-3-O-methyl-D-glucopyranoside
-
-
-
-
?
sucrose + 4-chloro-4-deoxy-D-galactose
D-glucose + beta-D-fructofuranosyl-(2->1)-4-deoxy-4-chloro-D-galactopyranoside
-
-
-
-
?
sucrose + 4-chloro-4-deoxy-D-galactose
D-glucose + beta-D-fructofuranosyl-(2->1)-4-deoxy-4-chloro-D-galactopyranoside
-
-
-
-
?
sucrose + 4-chloro-4-deoxy-D-glucose 6-acetate
D-glucose + beta-D-fructofuranosyl-(2->1)-4-chloro-4-deoxy-D-glucopyranoside 6-acetate
-
-
-
-
?
sucrose + 4-chloro-4-deoxy-D-glucose 6-acetate
D-glucose + beta-D-fructofuranosyl-(2->1)-4-chloro-4-deoxy-D-glucopyranoside 6-acetate
-
-
-
-
?
sucrose + 6-chloro-6-deoxy-D-glucose
D-glucose + beta-D-fructofuranosyl-(2->1)-6-chloro-6-deoxy-D-glucoside
-
-
-
-
?
sucrose + 6-chloro-6-deoxy-D-glucose
D-glucose + beta-D-fructofuranosyl-(2->1)-6-chloro-6-deoxy-D-glucoside
-
-
-
-
?
sucrose + 6-deoxy-D-glucose
D-glucose + beta-D-fructofuranosyl-(2->1)-6-deoxy-D-glucoside
-
-
-
-
?
sucrose + 6-deoxy-D-glucose
D-glucose + beta-D-fructofuranosyl-(2->1)-6-deoxy-D-glucoside
-
-
-
-
?
sucrose + 6-O-benzyl-D-glucose
D-glucose + beta-D-fructofuranosyl-(2->1)-6-O-benzyl-D-glucoside
-
-
-
-
?
sucrose + 6-O-benzyl-D-glucose
D-glucose + beta-D-fructofuranosyl-(2->1)-6-O-benzyl-D-glucoside
-
-
-
-
?
sucrose + 6-O-methyl-D-galactose
D-glucose + beta-D-fructofuranosyl-(2->1)-6-O-methyl-D-galactoside
-
-
-
-
?
sucrose + 6-O-methyl-D-galactose
D-glucose + beta-D-fructofuranosyl-(2->1)-6-O-methyl-D-galactoside
-
-
-
-
?
sucrose + 6-O-methyl-D-glucose
D-glucose + beta-D-fructofuranosyl-(2->1)--6-O-methyl-D-glucoside
-
-
-
-
?
sucrose + 6-O-methyl-D-glucose
D-glucose + beta-D-fructofuranosyl-(2->1)--6-O-methyl-D-glucoside
-
-
-
-
?
sucrose + cellobiose
D-glucose + beta-D-fructofuranosyl-(2->1)-cellobioside
-
-
-
-
?
sucrose + cellobiose
D-glucose + beta-D-fructofuranosyl-(2->1)-cellobioside
-
-
-
-
?
sucrose + D-arabinose
D-glucose + beta-D-fructofuranosyl-(2->1)-D-arabinoside
-
-
-
-
?
sucrose + D-arabinose
D-glucose + beta-D-fructofuranosyl-(2->1)-D-arabinoside
-
-
-
-
?
sucrose + D-galactose
D-glucose + beta-D-fructofuranosyl-(2->1)-D-galactopyranoside
-
-
-
-
?
sucrose + D-galactose
D-glucose + beta-D-fructofuranosyl-(2->1)-D-galactopyranoside
-
-
-
-
?
sucrose + D-galactose 6-acetate
D-glucose + beta-D-fructofuranosyl-(2->1)-D-6-O-acetyl-galactopyranoside
-
-
-
-
?
sucrose + D-galactose 6-acetate
D-glucose + beta-D-fructofuranosyl-(2->1)-D-6-O-acetyl-galactopyranoside
-
-
-
-
?
sucrose + D-gluconic acid
D-glucose + beta-D-fructofuranosyl-(2->1)-D-gluconic acid
-
-
-
-
?
sucrose + D-gluconic acid
D-glucose + beta-D-fructofuranosyl-(2->1)-D-gluconic acid
-
-
-
-
?
sucrose + D-glucose 6-acetate
D-glucose + beta-D-fructofuranosyl-(2->1)-6-O-acetyl-D-glucoside
-
-
-
-
?
sucrose + D-glucose 6-acetate
D-glucose + beta-D-fructofuranosyl-(2->1)-6-O-acetyl-D-glucoside
-
-
-
-
?
sucrose + D-glucose 6-phosphate
D-glucose + beta-D-fructofuranosyl-(2->1)-D-glucopyranoside 6-phosphate
-
-
-
-
?
sucrose + D-glucose 6-phosphate
D-glucose + beta-D-fructofuranosyl-(2->1)-D-glucopyranoside 6-phosphate
-
-
-
-
?
sucrose + D-mannose
D-glucose + beta-D-fructofuranosyl-(2->1)-D-mannopyranoside
-
-
-
-
?
sucrose + D-mannose
D-glucose + beta-D-fructofuranosyl-(2->1)-D-mannopyranoside
-
-
-
-
?
sucrose + D-ribose
D-glucose + beta-D-fructofuranosyl-(2->1)-D-riboside
-
-
-
-
?
sucrose + D-ribose
D-glucose + beta-D-fructofuranosyl-(2->1)-D-riboside
-
-
-
-
?
sucrose + D-xylose
D-glucose + beta-D-fructofuranosyl-(2->1)-alpha-D-xylopyranoside
-
-
-
-
?
sucrose + D-xylose
D-glucose + beta-D-fructofuranosyl-(2->1)-alpha-D-xylopyranoside
-
-
-
-
?
sucrose + isomaltose
D-glucose + beta-D-fructofuranosyl-(2->1)-isomaltoside
-
-
-
-
?
sucrose + isomaltose
D-glucose + beta-D-fructofuranosyl-(2->1)-isomaltoside
-
-
-
-
?
sucrose + L-arabinose
D-glucose + beta-D-fructofuranosyl-(2->1)-L-arabinoside
-
-
-
-
?
sucrose + L-arabinose
D-glucose + beta-D-fructofuranosyl-(2->1)-L-arabinoside
-
-
-
-
?
sucrose + L-fucose
D-glucose + beta-D-fructofuranosyl-(2->1)-L-fucoside
-
-
-
-
?
sucrose + L-fucose
D-glucose + beta-D-fructofuranosyl-(2->1)-L-fucoside
-
-
-
-
?
sucrose + L-rhamnose
D-glucose + beta-D-fructofuranosyl-(2->1)-L-rhamnoside
-
-
-
-
?
sucrose + L-rhamnose
D-glucose + beta-D-fructofuranosyl-(2->1)-L-rhamnoside
-
-
-
-
?
sucrose + lactose
D-glucose + beta-D-fructofuranosyl-(2->1)-lactoside
-
-
-
-
?
sucrose + lyxose
D-glucose + beta-D-fructofuranosyl-(2->1)-lyxoside
-
-
-
-
?
sucrose + maltohexaose
D-glucose + beta-D-fructofuranosyl-(2->1)-maltohexaoside
-
-
-
-
?
sucrose + maltohexaose
D-glucose + beta-D-fructofuranosyl-(2->1)-maltohexaoside
-
-
-
-
?
sucrose + maltopentaose
D-glucose + beta-D-fructofuranosyl-(2->1)-maltopentaoside
-
-
-
-
?
sucrose + maltopentaose
D-glucose + beta-D-fructofuranosyl-(2->1)-maltopentaoside
-
-
-
-
?
sucrose + maltose
D-glucose + beta-D-fructofuranosyl-(2->1)-maltoside
-
-
-
-
?
sucrose + maltotriose
D-glucose + beta-D-fructofuranosyl-(2->1)-maltotrioside
-
-
-
-
?
sucrose + maltotriose
D-glucose + beta-D-fructofuranosyl-(2->1)-maltotrioside
-
-
-
-
?
sucrose + melibiose
D-glucose + beta-D-fructofuranosyl-(2->1)-melibioside
-
-
-
-
?
sucrose + melibiose
D-glucose + beta-D-fructofuranosyl-(2->1)-melibioside
-
-
-
-
?
sucrose + xylitol
D-glucose + beta-D-fructofuranosyl-(2->1)-xylitol
-
-
-
-
?
additional information
?
-
-
when oligosaccharide acceptors are used, the acceptor activity decreases with increasing size, as in the homologous series maltose, maltotriose, maltotetrose, etc., reactivity also decreases with the size of the molecule in the homologous series sucrose, raffinose, stachyose, and verbascose, inulin and levan, and also levan that is partially hydrolysed with acid, do not act as donors, lactulose, isomaltulose, D-glucose-1-phosphate, methyl beta-D-glucoside, and D-xylulose are unreactive
-
-
?
additional information
?
-
Bacillus subtilis NCIB 11871
-
when oligosaccharide acceptors are used, the acceptor activity decreases with increasing size, as in the homologous series maltose, maltotriose, maltotetrose, etc., reactivity also decreases with the size of the molecule in the homologous series sucrose, raffinose, stachyose, and verbascose, inulin and levan, and also levan that is partially hydrolysed with acid, do not act as donors, lactulose, isomaltulose, D-glucose-1-phosphate, methyl beta-D-glucoside, and D-xylulose are unreactive
-
-
?
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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
fructose donor + fructose acceptor
D-aldose + D-aldosyl beta-D-fructoside
-
-
the products can act as acceptors for further reactions, leading to oligosaccharides or polysaccharides
?
fructose donor + fructose acceptor
D-aldose + D-aldosyl beta-D-fructoside
-
-
the products can act as acceptors for further reactions, leading to oligosaccharides or polysaccharides
?
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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
additional information
-
p-hydroxymercuribenzoate does not affect fructosyl transferase activity, the fructosyl transferase is completely resistant to endogenous proteases and to trypsin
-
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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
sucrose
-
the fructosyl transferase activity in strain NCIB 11871 is induced only by sucrose, other sugars tested as inducers (glucose, fructose, maltose, and cellobiose) are ineffective
additional information
-
the fructosyl transferase is unaffected by anionic, cationic, or nonionic detergents such as SDS, cetyltrimethylammonium bromide, and Triton X-100
-
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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Dehydration
Use of spent osmotic solutions for the production of fructooligosaccharides by Aspergillus oryzae N74.
Dehydration
Water stress drastically reduces root growth and inulin yield in Cichorium intybus (var. sativum) independently of photosynthesis.
Dental Caries
Biochemical characterization and evaluation of virulence of a fructosyltransferase-deficient mutant of Streptococcus mutans V403.
Dental Caries
Differential expression profiles of Streptococcus mutans ftf, gtf and vicR genes in the presence of dietary carbohydrates at early and late exponential growth phases.
Dental Caries
Immunization with dextransucrases, levansucrases, and glycosidic hydrolases from oral streptococci. II. Immunization with glucosyltransferases, fructosyltransferases, and glycosidic hydrolases from oral streptococci in monkeys.
Dental Caries
Regulation of the gtfBC and ftf genes of Streptococcus mutans in biofilms in response to pH and carbohydrate.
Periodontal Diseases
Effects of biosurfactant produced by Lactobacillus casei on gtfB, gtfC, and ftf gene expression level in S. mutans by real-time RT-PCR.
Periodontal Diseases
Effects of Lactobacillus reuteri-derived biosurfactant on the gene expression profile of essential adhesion genes (gtfB, gtfC and ftf) of Streptococcus mutans.
Stomatognathic Diseases
In vitro real-time interactions of cranberry constituents with immobilized fructosyltransferase.
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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
additional information
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the purified enzyme is concentrated 33fold and has an activity of 32 nmol/ml/min