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Information on EC 2.1.1.353 - demethylluteothin O-methyltransferase

for references in articles please use BRENDA:EC2.1.1.353

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IUBMB Comments

The enzyme, characterized from the bacterium Streptomyces thioluteus, participates in the biosynthesis of the antibiotic aureothin. An orthologous enzyme in the bacteria Streptomyces orinoci and Streptomyces spectabilis catalyses a similar reaction in the biosynthesis of spectinabilin.

The expected taxonomic range for this enzyme is: Streptomyces thioluteus

Synonyms
AurI, aurl, gamma-pyrone methyltransferase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + demethylluteothin = S-adenosyl-L-homocysteine + luteothin
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
aureothin biosynthesis, spectinabilin biosynthesis
Highest Expressing Human Cell Lines
Cell Line Links Gene Links