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Ligand S-adenosyl-L-homocysteine

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Basic Ligand Information

Molecular Structure
Picture of S-adenosyl-L-homocysteine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
Molfile
C14H20N6O5S
S-adenosyl-L-homocysteine
ZJUKTBDSGOFHSH-WFMPWKQPSA-N
Synonyms:
(2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}sulfanyl)butanoic acid, 5'-deoxy-5'-S-adenosyl-L-homocysteine, adenosyl-L-homocysteine, adenosylhomocysteine, AdoCys, Analogs of S-adenosyl-L-homocysteine, S-(5'-adenosyl)-L-homocysteine, S-5'-adenosyl-L-homocysteine, S-adenosyl-homocysteine, S-adenosyl-L-homocystein, S-adenosyl-L-homocysteine analogs, S-Adenosyl-L-homocysteine structural analogues, S-adenosylhomocysteine, S-adenosyl homocysteine, S-formycinylhomocysteine, Structure analogues of S-adenosyl-L-homocysteine

Related pathways

Pathway Source
Pathways
MetaCyc
(+)-pisatin biosynthesis, (S)-reticuline biosynthesis I, (S)-reticuline biosynthesis II, 1,3,5-trimethoxybenzene biosynthesis, 1-methylpyrrolinium biosynthesis more


Show all pahtways known for Show all BRENDA pathways known for S-adenosyl-L-homocysteine

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (36 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-L-homocysteine + (S)-reticuline = S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine
show the reaction diagram
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S-adenosyl-L-homocysteine + H2O = adenosine + L-homocysteine
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (3728 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2 [methionine synthase]-cob(II)alamin + NADPH + H+ + 2 S-adenosyl-L-methionine = 2 [methionine synthase]-methylcob(I)alamin + 2 S-adenosylhomocysteine + NADP+
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S-adenosyl-L-methionine + L-homocysteine = S-adenosyl-L-homocysteine + L-methionine
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S-adenosyl-L-methionine + demethylmacrocin = S-adenosyl-L-homocysteine + macrocin
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S-adenosyl-L-methionine + 6-hydroxymellein = S-adenosyl-L-homocysteine + 6-methoxymellein
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485093, -
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S-adenosyl-L-methionine + 6-demethylsterigmatocystin = S-adenosyl-L-homocysteine + sterigmatocystin
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S-adenosyl-L-methionine + sterigmatocystin = S-adenosyl-L-homocysteine + 8-O-methylsterigmatocystin
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S-adenosyl-L-methionine + anthranilate = S-adenosyl-L-homocysteine + N-methylanthranilate
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S-Adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine = S-Adenosyl-L-homocysteine + (S)-reticuline
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S-adenosyl-L-methionine + 10-hydroxydihydrosanguinarine = S-adenosyl-L-homocysteine + dihydrochelirubine
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S-adenosyl-L-methionine + myo-inositol = S-adenosyl-L-homocysteine + 1D-4-O-methyl-myo-inositol
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S-adenosyl-L-methionine + cobalt-precorrin-2 = S-adenosyl-L-homocysteine + cobalt-precorrin-3A
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S-adenosyl-L-methionine + cobalt-precorrin-6Y + 6 H+ = S-adenosyl-L-homocysteine + cobalt-precorrin-8X + 2 H2O
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S-adenosyl-L-methionine + 3'-demethylstaurosporine = S-adenosyl-L-homocysteine + staurosporine
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S-adenosyl-L-methionine + jasmonate = S-adenosyl-L-homocysteine + methyl jasmonate
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645945, -
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S-adenosyl-L-methionine + trans-aconitate = S-adenosyl-L-homocysteine + (E)-3-(methoxycarbonyl)pent-2-enedioate
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S-adenosyl-L-methionine + trans-aconitate = S-adenosyl-L-homocysteine + (E)-2-(methoxycarbonylmethyl)butenedioate
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S-adenosyl-L-methionine + a fatty acid = S-adenosyl-L-homocysteine + a fatty acid methyl ester
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S-adenosyl-L-methionine + 7,4'-dihydroxyisoflavone = S-adenosyl-L-homocysteine + 4'-hydroxy-7-methoxyisoflavone
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S-adenosyl-L-methionine + cobalt-factor II = S-adenosyl-L-homocysteine + cobalt-factor III
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S-adenosyl-L-methionine + precorrin-5 + H2O = S-adenosyl-L-homocysteine + precorrin-6A + acetate
show the reaction diagram
- , 3209, 644278
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S-adenosyl-L-methionine + vitexin 2''-O-beta-L-rhamnoside = S-adenosyl-L-homocysteine + 7-O-methylvitexin 2''-O-beta-L-rhamnoside
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S-adenosyl-L-methionine + isoliquiritigenin = S-adenosyl-L-homocysteine + 2'-O-methylisoliquiritigenin
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S-adenosyl-L-methionine + xanthosine = S-adenosyl-L-homocysteine + 7-methylxanthosine
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S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid methylene fatty acid
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S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + N,N,N-trimethylglycine
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4'-demethylrebeccamycin + S-adenosyl-L-methionine = rebeccamycin + S-adenosyl-L-homocysteine
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S-adenosyl-L-methionine + chloride = S-adenosyl-L-homocysteine + methyl chloride
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S-adenosyl-L-methionine + uridine2552 in 23S rRNA = S-adenosyl-L-homocysteine + 2'-O-methyluridine2552 in 23S rRNA
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S-adenosyl-L-methionine + uridine2791 in 21S rRNA = S-adenosyl-L-homocysteine + 2'-O-methyluridine2791 in 21S rRNA
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S-adenosyl-L-methionine + guanine527 in 16S rRNA = S-adenosyl-L-homocysteine + N7-methylguanine527 in 16S rRNA
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S-adenosyl-L-methionine + guanine1207 in 16S rRNA = S-adenosyl-L-homocysteine + N2-methylguanine1207 in 16S rRNA
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S-adenosyl-L-methionine + guanine1835 in 23S rRNA = S-adenosyl-L-homocysteine + N2-methylguanine1835 in 23S rRNA
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S-adenosyl-L-methionine + cytosine967 in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine967 in 16S rRNA
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S-adenosyl-L-methionine + pseudouridine1915 in 23S rRNA = S-adenosyl-L-homocysteine + N3-methylpseudouridine1915 in 23S rRNA
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S-adenosyl-L-methionine + 1,4-alpha-D-glucooligosaccharide = S-adenosyl-L-homocysteine + oligosaccharide containing 6-methyl-D-glucose units
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485196, -
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S-adenosyl-L-methionine + adenine1618 in 23S rRNA = S-adenosyl-L-homocysteine + 6-methyladenine1618 in 23S rRNA
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S-adenosyl-L-methionine + guanosine2251 in 23S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylguanosine2251 in 23S rRNA
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S-adenosyl-L-methionine + cytidine2498 in 23S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytidine2498 in 23S rRNA
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S-adenosyl-L-methionine + guanine745 in 23S rRNA = S-adenosyl-L-homocysteine + N1-methylguanine745 in 23S rRNA
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S-adenosyl-L-methionine + uracil1939 in 23S rRNA = S-adenosyl-L-homocysteine + 5-methyluracil1939 in 23S rRNA
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S-adenosyl-L-methionine + uracil1498 in 16S rRNA = S-adenosyl-L-homocysteine + N3-methyluracil1498 in 16S rRNA
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cobalt-precorrin-5B + S-adenosyl-L-methionine = cobalt-precorrin-6A + S-adenosyl-L-homocysteine
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cobalt-precorrin-6B + S-adenosyl-L-methionine = cobalt-precorrin-7 + S-adenosyl-L-homocysteine + CO2
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S-adenosyl-L-methionine + uridine2479 in 23S rRNA = S-adenosyl-L-homocysteine + 2'-O-methyluridine2479 in 23S rRNA
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S-adenosyl-L-methionine + guanine2535 in 23S rRNA = S-adenosyl-L-homocysteine + N1-methylguanine2535 in 23S rRNA
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S-adenosyl-L-methionine + uridine44 in tRNASer = S-adenosyl-L-homocysteine + 2'-O-methyluridine44 in tRNASer
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S-adenosyl-L-methionine + guanine10 in tRNA = S-adenosyl-L-homocysteine + N2-methylguanine10 in tRNA
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2 S-adenosyl-L-methionine + adenine57/adenine58 in tRNA = 2 S-adenosyl-L-homocysteine + N1-methyladenine57/N1-methyladenine58 in tRNA
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S-adenosyl-L-methionine + adenine37 in tRNA1(Val) = S-adenosyl-L-homocysteine + N6-methyladenine37 in tRNA1(Val)
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S-adenosyl-L-methionine + cytidine1409 in 16S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytidine1409 in 16S rRNA
show the reaction diagram
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S-adenosyl-L-methionine + adenosine1067 in 23S rRNA = S-adenosyl-L-homocysteine + 2'-O-methyladenosine1067 in 23S rRNA
show the reaction diagram
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2 S-adenosyl-L-methionine + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose = 2 S-adenosyl-L-homocysteine + dTDP-3-dimethylamino-3,6-dideoxy-alpha-D-galactopyranose
show the reaction diagram
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S-adenosyl-L-methionine + mycinamicin VI = S-adenosyl-L-homocysteine + mycinamicin III
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S-adenosyl-L-methionine + L-olivosyl-erythronolide B = S-adenosyl-L-homocysteine + L-oleandrosyl-erythronolide B
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S-adenosyl-L-methionine + 5-guanidino-2-oxopentanoate = S-adenosyl-L-homocysteine + 5-guanidino-3-methyl-2-oxopentanoate
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S-adenosyl-L-methionine + geranyl diphosphate = S-adenosyl-L-homocysteine + (E)-2-methylgeranyl diphosphate
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S-adenosyl-L-methionine + pseudouridine54 in tRNA = S-adenosyl-L-homocysteine + N1-methylpseudouridine54 in tRNA
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S-adenosyl-L-methionine + 4-dimethylallyl-L-tryptophan = S-adenosyl-L-homocysteine + 4-dimethylallyl-L-abrine
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S-adenosyl-L-methionine + guanine2069 in 23S rRNA = S-adenosyl-L-homocysteine + N7-methylguanine2069 in 23S rRNA
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S-adenosyl-L-methionine + tellurite = S-adenosyl-L-homocysteine + methanetelluronate
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S-adenosyl-L-methionine + (+)-6a-hydroxymaackiain = S-adenosyl-L-homocysteine + (+)-pisatin
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S-adenosyl-L-methionine + gibberellin A9 = S-adenosyl-L-homocysteine + methyl gibberellin A9
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S-adenosyl-L-methionine + anthranilate = S-adenosyl-L-homocysteine + O-methyl anthranilate
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S-adenosyl-L-methionine + trans-anol = S-adenosyl-L-homocysteine + trans-anethole
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S-adenosyl-L-methionine + emodin = S-adenosyl-L-homocysteine + questin
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S-adenosyl-L-methionine + 8-demethylnovobiocic acid = S-adenosyl-L-homocysteine + novobiocic acid
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S-adenosyl-L-methionine + demethyldecarbamoylnovobiocin = S-adenosyl-L-homocysteine + decarbamoylnovobiocin
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S-adenosyl-L-methionine + adenine2142 in 25S rRNA = S-adenosyl-L-homocysteine + N1-methyladenine2142 in 25S rRNA
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S-adenosyl-L-methionine + aklanonate = S-adenosyl-L-homocysteine + methyl aklanonate
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cobalt-precorrin-7 + S-adenosyl-L-methionine = cobalt-precorrin-8 + S-adenosyl-L-homocysteine
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S-adenosyl-L-methionine + 6-hydroxytryprostatin B = S-adenosyl-L-homocysteine + tryprostatin A
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S-adenosyl-L-methionine + [ribosomal protein L3]-L-glutamine = S-adenosyl-L-homocysteine + [ribosomal protein L3]-N5-methyl-L-glutamine
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S-adenosyl-L-methionine + N-terminal L-alanine-[cypemycin] = S-adenosyl-L-homocysteine + N-terminal N,N-dimethyl-L-alanine-[cypemycin]
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S-adenosyl-L-methionine + 3-hydroxy-5-methylnaphthoate = S-adenosyl-L-homocysteine + 3-methoxy-5-methylnaphthoate
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S-adenosyl-L-methionine + 2,7-dihydroxy-5-methyl-1-naphthoate = S-adenosyl-L-homocysteine + 2-hydroxy-7-methoxy-5-methyl-1-naphthoate
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S-adenosyl-L-methionine + L-tyrosine = S-adenosyl-L-homocysteine + 3-methyl-L-tyrosine
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S-adenosyl-L-methionine + 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C = S-adenosyl-L-homocysteine + 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C
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S-adenosyl-L-methionine + 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C = S-adenosyl-L-homocysteine + 8-demethyl-8-(2,3-dimethyl-alpha-L-rhamnosyl)-tetracenomycin C
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S-adenosyl-L-methionine + 8-demethyl-8-(2,3-O-dimethyl-alpha-L-rhamnosyl)-tetracenomycin C = S-adenosyl-L-homocysteine + 8-demethyl-8-(2,3,4-O-trimethyl-alpha-L-rhamnosyl)-tetracenomycin C
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2 S-adenosyl-L-methionine + cytidine 5'-[[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate] + reduced acceptor = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + cytidine 5'-[[hydroxy(2-hydroxypropyl)phosphonoyl]phosphate] + oxidized acceptor
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S-adenosyl-L-methionine + cytosine2278 in 25S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine2278 in 25S rRNA
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S-adenosyl-L-methionine + uracil2843 in 25S rRNA = S-adenosyl-L-homocysteine + N3-methyluracil2843 in 25S rRNA
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S-adenosyl-L-methionine + uracil2634 in 25S rRNA = S-adenosyl-L-homocysteine + N3-methyluracil2634 in 25S rRNA
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4 S-adenosyl-L-methionine + 2-[(3S)-3-carboxy-3-aminopropyl]-L-histidine-[translation elongation factor 2] = 4 S-adenosyl-L-homocysteine + diphthine methyl ester-[translation elongation factor 2]
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S-adenosyl-L-methionine + 27-O-demethylrifamycin SV = S-adenosyl-L-homocysteine + rifamycin SV
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S-adenosyl-L-methionine + a (4E,8E)-sphinga-4,8-dienine ceramide = S-adenosyl-L-homocysteine + a 9-methyl-(4E,8E)-sphinga-4,8-dienine ceramide
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S-adenosyl-L-methionine + [trehalose-6-phosphate synthase]-L-cysteine = S-adenosyl-L-homocysteine + [trehalose-6-phosphate synthase]-S-methyl-L-cysteine
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S-adenosyl-L-methionine + (-)-pluviatolide = S-adenosyl-L-homocysteine + (-)-bursehernin
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S-adenosyl-L-methionine + dTDP-4-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose = S-adenosyl-L-homocysteine + dTDP-alpha-D-forosamine
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2 S-adenosyl-L-methionine + N-acetyldemethylphosphinothricin + reduced acceptor = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + N-acetylphosphinothricin + oxidized acceptor
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S-adenosyl-L-methionine + phenazine-1-carboxylate = S-adenosyl-L-homocysteine + 5-methylphenazine-1-carboxylate
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S-adenosyl-L-methionine + N-demethylindolmycin = S-adenosyl-L-homocysteine + indolmycin
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S-adenosyl-L-methionine + (-)-5'-demethylyatein = S-adenosyl-L-homocysteine + (-)-yatein
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S-adenosyl-L-methionine + guanosine18 in tRNATyr = S-adenosyl-L-homocysteine + 2'-O-methylguanosine18 in tRNATyr
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2 S-adenosyl-L-methionine + protoheme + 2 reduced flavodoxin = S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + anaerobilin + Fe2+ + 2 oxidized flavodoxin
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S-adenosyl-L-methionine + an ornithine lipid = S-adenosyl-L-homocysteine + an N,N,N-trimethylornithine lipid
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S-adenosyl-L-methionine + (+)-kolavelool = S-adenosyl-L-homocysteine + (+)-O-methylkolavelool
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S-adenosyl-L-methionine + nocamycin E = S-adenosyl-L-homocysteine + nocamycin I
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S-adenosyl-L-methionine + 3-O-acetyl-4'-O-demethylpapaveroxine = S-adenosyl-L-homocysteine + 3-O-acetylpapaveroxine
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S-adenosyl-L-methionine + demethylluteothin = S-adenosyl-L-homocysteine + luteothin
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S-adenosyl-L-methionine + (2E,6E)-farnesyl diphosphate = S-adenosyl-L-homocysteine + pre-sodorifen diphosphate
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S-adenosyl-L-methionine + 3,3'-di-O-methyl-4alpha-mannobiose = S-adenosyl-L-homocysteine + 1,3,3'-tri-O-methyl-4alpha-mannobiose
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S-adenosyl-L-methionine + a [histone H3]-N6,N6-dimethyl-L-lysine9 = S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine9
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S-adenosyl-L-methionine + (2R)-2-hydroxy-4-(methylsulfanyl)butanoate = S-adenosyl-L-homocysteine + (2R)-4-(dimethylsulfaniumyl)-2-hydroxybutanoate
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S-adenosyl-L-methionine + O-demethylpuromycin = S-adenosyl-L-homocysteine + puromycin
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S-adenosyl-L-methionine + 3-amino-2,4-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-amino-2-hydroxy-4-methoxybenzoate
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S-adenosyl-L-methionine + 5-dehydro-6-demethoxy-6-hydroxyfumagillol = S-adenosyl-L-homocysteine + 5-dehydrofumagillol
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S-adenosyl-L-methionine + myo-inositol = S-adenosyl-L-homocysteine + 1D-3-O-methyl-myo-inositol + H+
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S-adenosyl-L-methionine + gentamicin X2 = S-adenosyl-L-homocysteine + G418
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S-adenosyl-L-methionine + norajmaline = S-adenosyl-L-homocysteine + ajmaline
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S-adenosyl-L-methionine + ajmaline = S-adenosyl-L-homocysteine + 4-methylajmaline
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S-adenosyl-L-methionine + 10-hydroxystrychnine = S-adenosyl-L-homocysteine + beta-colubrine
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2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L-homocysteine + pterostilbene
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S-adenosyl-L-methionine + myo-inositol = S-adenosyl-L-homocysteine + D-bornesitol
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S-adenosyl-L-methionine + 6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol = S-adenosyl-L-homocysteine + 6-carboxymethyl-3,5-dimethyl-4-hydroxypyridin-2-ol
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S-adenosyl-L-methionine + nicotinate = S-adenosyl-L-homocysteine + methyl nicotinate
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zymosterol + S-adenosyl-L-methionine = fecosterol + S-adenosyl-L-homocysteine
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S-adenosyl-L-methionine + putrescine = S-adenosyl-L-homocysteine + N-methylputrescine
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S-adenosyl-L-methionine + adenine in tRNA = S-adenosyl-L-homocysteine + N6-methyladenine in tRNA
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S-adenosyl-L-methionine + cytochrome c L-lysine = S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine
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S-adenosyl-L-methionine + calmodulin L-lysine = S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine
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S-adenosyl-L-methionine + 5-aminomethyl-2-thiouridine in tRNA = S-adenosyl-L-homocysteine + 5-methylaminomethyl-2-thiouridylate in tRNA
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S-adenosyl-L-methionine + licodione = S-adenosyl-L-homocysteine + 2'-O-methyllicodione
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S-adenosyl-L-methionine + xanthotoxol = S-adenosyl-L-homocysteine + xanthotoxin
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S-adenosyl-L-methionine + isoorientin = S-adenosyl-L-homocysteine + isoscoparin
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S-adenosyl-L-methionine + 3',4',5,7-tetrahydroxy-3-methoxyflavone = S-adenosyl-L-homocysteine + 3',4',5-trihydroxy-3,7-dimethoxyflavone
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S-adenosyl-L-methionine + 3',4',5-trihydroxy-3,7-dimethoxyflavone = S-adenosyl-L-homocysteine + 3',5-dihydroxy-3,4',7-trimethoxyflavone
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S-adenosyl-L-methionine + 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone = S-adenosyl-L-homocysteine + 3',4',5-trihydroxy-3,6,7-trimethoxyflavone
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S-adenosyl-L-methionine + pyridine = S-adenosyl-L-homocysteine + N-methylpyridinium
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S-adenosyl-L-methionine + 3-hydroxyanthranilate = S-adenosyl-L-homocysteine + 3-hydroxy-4-methylanthranilate
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S-adenosyl-L-methionine + 16-methoxy-2,3-dihydro-3-hydroxytabersonine = S-adenosyl-L-homocysteine + deacetoxyvindoline
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S-adenosyl-L-methionine + cytosine32 in tRNASer/Thr = S-adenosyl-L-homocysteine + N3-methylcytosine32 in tRNASer/Thr
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S-adenosyl-L-methionine + [Sul7d-chromatin-protein] L-lysine = S-adenosyl-L-homocysteine + [Sul7d-chromatin-protein] N6-methyl-L-lysine
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S-adenosyl-L-methionine + DNA containing the recognition sequence GGCC = S-adenosyl-L-homocysteine + DNA containing the recognition sequence GGmCC
show the reaction diagram
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S-adenosyl-L-methionine + DNA containing the recognition sequence 5'-GTAC-3' = S-adenosyl-L-homocysteine + DNA containing the methylated recognition sequence 5'-GTm6AC-3'
show the reaction diagram
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S-adenosyl-L-methionine + uridine1369 in 16S rRNA = S-adenosyl-L-homocysteine + 2'-O-methyluridine1369 in 16S rRNA
show the reaction diagram
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S-adenosyl-L-methionine + guanine1370 in 16S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylguanine1370 in 16S rRNA
show the reaction diagram
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guanine1145 in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylguanine1145 in 16S rRNA + S-adenosyl-L-homocysteine
show the reaction diagram
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S-adenosyl-L-methionine + 4-methoxybenzoate = methyl 4-methoxybenzoate + S-adenosyl-L-homocysteine
show the reaction diagram
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S-adenosyl-L-methionine + adenine1322 in 28S rRNA = S-adenosyl-L-homocysteine + N1-methyladenine1322 in 28S rRNA
show the reaction diagram
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tRNAHis + S-adenosyl-L-methionine = methylated tRNAHis + S-adenosyl-L-homocysteine
show the reaction diagram
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2 S-adenosyl-L-methionine + [eEF2]-L-lysine613 = 2 S-adenosyl-L-homocysteine + [eEF2]-N6,N6-dimethyl-L-lysine613
show the reaction diagram
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3 S-adenosyl-L-methionine + [eEF1A]-L-lysine36 = 3 S-adenosyl-L-homocysteine + [eEF1A]-N6,N6,N6-trimethyl-L-lysine36
show the reaction diagram
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3 S-adenosyl-L-methionine + [ATPSc]-L-lysine43 = 3 S-adenosyl-L-homocysteine + [ATPSc]-N6,N6,N6-trimethyl-L-lysine43
show the reaction diagram
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3 S-adenosyl-L-methionine + [adenine nucleotide translocase]-L-lysine52 = 3 S-adenosyl-L-homocysteine + [adenine nucleotide translocase]-N6,N6,N6-trimethyl-L-lysine52
show the reaction diagram
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3 S-adenosyl-L-methionine + [Ca2+-binding protein CaM]-L-lysine115 = 3 S-adenosyl-L-homocysteine + [Ca2+-binding protein CaM]-N6,N6,N6-trimethyl-L-lysine115
show the reaction diagram
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3 S-adenosyl-L-methionine + [KIN17]-L-lysine135 = 3 S-adenosyl-L-homocysteine + [KIN17]-N6,N6,N6-trimethyl-L-lysine135
show the reaction diagram
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[ribosomal protein RPL3]-L-histidine245 + S-adenosyl-L-methionine = [ribosomal protein RPL3]-N3-methyl-L-histidine245 + S-adenosyl-L-homocysteine
show the reaction diagram
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3 S-adenosyl-L-methionine + [eEF1A]-L-lysine79 = 3 S-adenosyl-L-homocysteine + [eEF1A]-N6,N6,N6-trimethyl-L-lysine79
show the reaction diagram
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S-adenosyl-L-methionine + 1,3-dimethylxanthine = S-adenosyl-L-homocysteine + 1,3,7-trimethylxanthine
show the reaction diagram
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S-adenosyl-L-methionine + adenosine in 18S rRNA = S-adenosyl-L-homocysteine + N6-methyladenosine in 18S rRNA
show the reaction diagram
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S-adenosyl-L-methionine + 1,3,7-trimethylurate = S-adenosyl-L-homocysteine + theacrine
show the reaction diagram
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S-adenosyl-L-methionine + xanthosine = S-adenosyl-L-homocysteine + 3-methylxanthosine
show the reaction diagram
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S-adenosyl-L-methionine + uridine3039 in 16S rRNA = S-adenosyl-L-homocysteine + 2'-O-methyluridine3039 in 16S rRNA
show the reaction diagram
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S-adenosyl-L-methionine + guanine2574 in 23S rRNA = S-adenosyl-L-homocysteine + N7-methylguanine2574 in 23S rRNA
show the reaction diagram
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2 S-adenosyl-L-methionine + 7'-O-demethylcephaeline = 2 S-adenosyl-L-homocysteine + emetine
show the reaction diagram
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acetyl-CoA + malonyl-CoA + [2-methylbutanoate polyketide synthase] + 2 NADPH + 2 H+ + S-adenosyl-L-methionine = (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] + 2 CoA + CO2 + 2 NADP+ + S-adenosyl-L-homocysteine + H2O
show the reaction diagram
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N6-dimethylallyladenine37 in tRNA + sulfur-(sulfur carrier) + 2 S-adenosyl-L-methionine = 2-methylthio-N6-dimethylallyladenine37 in tRNA + S-adenosyl-L-homocysteine + (sulfur carrier) + L-methionine + 5'-deoxyadenosine
show the reaction diagram
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N6-L-threonylcarbamoyladenine37 in tRNA + sulfur-(sulfur carrier) + 2 S-adenosyl-L-methionine = 2-methylthio-N6-L-threonylcarbamoyladenine37 in tRNA + S-adenosyl-L-homocysteine + (sulfur carrier) + L-methionine + 5'-deoxyadenosine
show the reaction diagram
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2 ATP + S-adenosyl-L-methionine + anthranilate + L-phenylalanine = cyclopeptine + 2 AMP + 2 diphosphate + S-adenosyl-L-homocysteine
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (92 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-L-homocysteine + H2O + O2 = 4-thioadenosyl-2-oxobutyrate + NH3 + H2O2
show the reaction diagram
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S-adenosyl-L-homocysteine + (S)-reticuline = S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine
show the reaction diagram
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S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine = S-adenosyl-L-methionine + phosphatidylethanolamin
show the reaction diagram
S-adenosyl-L-homocysteine + [large subunit of spinach Rubisco-human carbonic anhydrase II fusion protein]-L-lysine = S-adenosyl-L-homocysteine + [large subunit of spinach Rubisco-human carbonic anhydrase II fusion protein]-N6,N6,N6-trimethyl-L-lysine
show the reaction diagram
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S-adenosyl-L-homocysteine + 6,7-dihydroxy-3'-methoxyisoflavone = ?
show the reaction diagram
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S-5'-adenosyl-L-homocysteine + H2O = ?
show the reaction diagram
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S-adenosyl-L-homocysteine + H2O = adenosine + L-homocysteine
show the reaction diagram
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S-adenosyl-L-homocysteine + H2O = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (17606 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-L-methionine + N-benzoyl-4-hydroxyanthranilate = S-adenosyl-L-homocysteine + N-benzoyl-4-methoxyanthranilate
show the reaction diagram
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S-adenosyl-L-methionine + glucuronoxylan D-glucuronate = S-adenosyl-L-homocysteine + glucuronoxylan 4-O-methyl-D-glucuronate
show the reaction diagram
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S-adenosyl-L-methionine + 10-hydroxydihydrosanguinarine = S-adenosyl-L-homocysteine + dihydrochelirubine
show the reaction diagram
7392, -
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S-adenosyl-L-methionine + 12-hydroxydihydrochelirubine = S-adenosyl-L-homocysteine + dihydromacarpine
show the reaction diagram
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S-Adenosyl-L-methionine + 6-O-methylnorlaudanosoline = S-Adenosyl-L-homocysteine + nororientaline
show the reaction diagram
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S-Adenosyl-L-methionine + [cytochrome c]-methionine = S-Adenosyl-L-homocysteine + [cytochrome c]-S-methyl-methionine
show the reaction diagram
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S-adenosyl-L-methionine + 3'-demethylstaurosporine = S-adenosyl-L-homocysteine + staurosporine
show the reaction diagram
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S-adenosyl-L-methionine + xanthosine = S-adenosyl-L-homocysteine + 7-methylxanthosine
show the reaction diagram
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S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + N,N,N-trimethylglycine
show the reaction diagram
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S-adenosyl-L-methionine + uridine2552 in 23S rRNA = S-adenosyl-L-homocysteine + 2'-O-methyluridine2552 in 23S rRNA
show the reaction diagram
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S-adenosyl-L-methionine + uridine2791 in 21S rRNA = S-adenosyl-L-homocysteine + 2'-O-methyluridine2791 in 21S rRNA
show the reaction diagram
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S-adenosyl-L-methionine + guanine527 in 16S rRNA = S-adenosyl-L-homocysteine + N7-methylguanine527 in 16S rRNA
show the reaction diagram
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S-adenosyl-L-methionine + guanine1207 in 16S rRNA = S-adenosyl-L-homocysteine + N2-methylguanine1207 in 16S rRNA
show the reaction diagram
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S-adenosyl-L-methionine + guanine1835 in 23S rRNA = S-adenosyl-L-homocysteine + N2-methylguanine1835 in 23S rRNA
show the reaction diagram
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S-adenosyl-L-methionine + cytosine967 in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine967 in 16S rRNA
show the reaction diagram
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S-adenosyl-L-methionine + pseudouridine1915 in 23S rRNA = S-adenosyl-L-homocysteine + N3-methylpseudouridine1915 in 23S rRNA
show the reaction diagram
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S-adenosyl-L-methionine + 1,4-alpha-D-glucooligosaccharide = S-adenosyl-L-homocysteine + oligosaccharide containing 6-methyl-D-glucose units
show the reaction diagram
485196, -
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S-adenosyl-L-methionine + adenine1618 in 23S rRNA = S-adenosyl-L-homocysteine + 6-methyladenine1618 in 23S rRNA
show the reaction diagram
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S-adenosyl-L-methionine + guanosine2251 in 23S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylguanosine2251 in 23S rRNA
show the reaction diagram
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S-adenosyl-L-methionine + cytidine2498 in 23S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytidine2498 in 23S rRNA
show the reaction diagram
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S-adenosyl-L-methionine + guanine745 in 23S rRNA = S-adenosyl-L-homocysteine + N1-methylguanine745 in 23S rRNA
show the reaction diagram
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S-adenosyl-L-methionine + uracil1939 in 23S rRNA = S-adenosyl-L-homocysteine + 5-methyluracil1939 in 23S rRNA
show the reaction diagram
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S-adenosyl-L-methionine + cytosine1962 in 23S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine1962 in 23S rRNA
show the reaction diagram
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S-adenosyl-L-methionine + uracil1498 in 16S rRNA = S-adenosyl-L-homocysteine + N3-methyluracil1498 in 16S rRNA
show the reaction diagram
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cobalt-precorrin-5B + S-adenosyl-L-methionine = cobalt-precorrin-6A + S-adenosyl-L-homocysteine
show the reaction diagram
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cobalt-precorrin-6B + S-adenosyl-L-methionine = cobalt-precorrin-7 + S-adenosyl-L-homocysteine + CO2
show the reaction diagram
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S-adenosyl-L-methionine + uridine2479 in 23S rRNA = S-adenosyl-L-homocysteine + 2'-O-methyluridine2479 in 23S rRNA
show the reaction diagram
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S-adenosyl-L-methionine + guanine2535 in 23S rRNA = S-adenosyl-L-homocysteine + N1-methylguanine2535 in 23S rRNA
show the reaction diagram
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S-adenosyl-L-methionine + uridine44 in tRNASer = S-adenosyl-L-homocysteine + 2'-O-methyluridine44 in tRNASer
show the reaction diagram
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