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Information on EC 2.1.1.298 - ribosomal protein L3 N5-glutamine methyltransferase and Organism(s) Escherichia coli and UniProt Accession P39199

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IUBMB Comments
Modifies the glutamine residue in the glycylglycylglutamine (GGQ) motif of ribosomal protein L3 (Gln150 in the protein from the bacterium Escherichia coli). The enzyme does not act on peptide chain release factor 1 or 2.
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This record set is specific for:
Escherichia coli
UNIPROT: P39199
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The taxonomic range for the selected organisms is: Escherichia coli
The expected taxonomic range for this enzyme is: Bacteria, Archaea
Reaction Schemes
+
[ribosomal protein L3]-L-glutamine
=
+
[ribosomal protein L3]-N5-methyl-L-glutamine
Synonyms
prmb-type n5-glutamine methyltransferase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SYSTEMATIC NAME
IUBMB Comments
S-adenosyl-L-methionine:[ribosomal protein L3]-L-glutamine (N5-glutamine)-methyltransferase
Modifies the glutamine residue in the glycylglycylglutamine (GGQ) motif of ribosomal protein L3 (Gln150 in the protein from the bacterium Escherichia coli). The enzyme does not act on peptide chain release factor 1 or 2.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-methionine + [ribosomal protein L3]-L-glutamine
S-adenosyl-L-homocysteine + [ribosomal protein L3]-N5-methyl-L-glutamine
show the reaction diagram
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-methionine + [ribosomal protein L3]-L-glutamine
S-adenosyl-L-homocysteine + [ribosomal protein L3]-N5-methyl-L-glutamine
show the reaction diagram
the enzyme modifies the glutamine residue in the glycylglycylglutamine (GGQ) motif of ribosomal protein L3 (Gln150 in the protein from the bacterium Escherichia coli). The enzyme does not act on peptide chain release factor 1 or 2
-
-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
SwissProt
Manually annotated by BRENDA team
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Heurgue-Hamard, V.; Champ, S.; Engstrom, A.; Ehrenberg, M.; Buckingham, R.H.
The hemK gene in Escherichia coli encodes the N5-glutamine methyltransferase that modifies peptide release factors
EMBO J.
21
769-778
2002
Escherichia coli (P39199)
Manually annotated by BRENDA team