Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 2.1.1.245 - 5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein Co-methyltransferase and Organism(s) Archaeoglobus fulgidus and UniProt Accession O29871

for references in articles please use BRENDA:EC2.1.1.245
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
Catalyses the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin. Forms, together with EC 1.2.7.4, anaerobic carbon-monoxide dehydrogenase, and EC 2.3.1.169, CO-methylating acetyl-CoA synthase, the acetyl-CoA decarbonylase/synthase complex that catalyses the demethylation of acetyl-CoA in a reaction that also forms CO2. This reaction is a key step in methanogenesis from acetate.
Specify your search results
Select one or more organisms in this record: ?
This record set is specific for:
Archaeoglobus fulgidus
UNIPROT: O29871
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
hide
The taxonomic range for the selected organisms is: Archaeoglobus fulgidus
The expected taxonomic range for this enzyme is: Archaea, Bacteria
Reaction Schemes
hide
a [methyl-Co(III) corrinoid Fe-S protein]
+
tetrahydrosarcinapterin
=
a [Co(I) corrinoid Fe-S protein]
+
5-methyltetrahydrosarcinapterin
a [methyl-Co(III) corrinoid Fe-S protein]
+
=
a [Co(I) corrinoid Fe-S protein]
+
Synonyms
methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase, ch3-h4pteridine:cob(i)amide-protein methyltransferase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
AcdS
5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein Co-methyltransferase (EC 2.1.1.245), carbon-monoxide dehydrogenase (ferredoxin) (EC 1.2.7.4) and CO-methylating acetyl-CoA synthase (EC 2.3.1.169) form together the acetyl-CoA decarbonylase/synthase complex that catalyses the demethylation of acetyl-CoA in a reaction that also forms CO2
acetyl-CoA decarbonylase/synthase complex
5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein Co-methyltransferase (EC 2.1.1.245), carbon-monoxide dehydrogenase (ferredoxin) (EC 1.2.7.4) and CO-methylating acetyl-CoA synthase (EC 2.3.1.169) form together the acetyl-CoA decarbonylase/synthase complex that catalyses the demethylation of acetyl-CoA in a reaction that also forms CO2
cdhD
-
-
-
-
cdhE
-
-
-
-
PATHWAY SOURCE
PATHWAYS
-
-
SYSTEMATIC NAME
IUBMB Comments
5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein methyltransferase
Catalyses the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin. Forms, together with EC 1.2.7.4, anaerobic carbon-monoxide dehydrogenase, and EC 2.3.1.169, CO-methylating acetyl-CoA synthase, the acetyl-CoA decarbonylase/synthase complex that catalyses the demethylation of acetyl-CoA in a reaction that also forms CO2. This reaction is a key step in methanogenesis from acetate.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
SwissProt
Manually annotated by BRENDA team
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Dai, Y.R.; Reed, D.W.; Millstein, J.H.; Hartzell, P.L.; Grahame, D.A.; DeMoll, E.
Acetyl-CoA decarbonylase/synthase complex from Archaeoglobus fulgidus
Arch. Microbiol.
169
525-529
1998
Archaeoglobus fulgidus (O29871), Archaeoglobus fulgidus
Manually annotated by BRENDA team