Ligand view of tetrahydrosarcinapterin (11158 - DOMRFGVDYQUXCH-GPQOPNTJSA-N)

C₃₅H₅₂N₇O₁₉P

tetrahydrosarcinapterin

DOMRFGVDYQUXCH-GPQOPNTJSA-N

BRENDA

KEGG

Biosynthesis of cofactors, Carbon metabolism, Folate biosynthesis, Methane metabolism, Microbial metabolism in diverse environments

MetaCyc

methanogenesis from acetate, methyl-coenzyme M oxidation to CO2

2.1.1.245

a [methyl-Co(III) corrinoid Fe-S protein] + tetrahydrosarcinapterin = a [Co(I) corrinoid Fe-S protein] + 5-methyltetrahydrosarcinapterin

717236, 717755

-

2.1.1.86

5-methyl-5,6,7,8-tetrahydrosarcinapterin + coenzyme M = 5,6,7,8-tetrahydrosarcinapterin + methyl-coenzyme M

-

6.3.2.33

2 entries

1.2.7.4

tetrahydrosarcinapterin + acetyl-SCoA + H2O = methyltetrahydrosarcinapterin + CO2 + CoASH

390474, 390465

-

2.1.1.245

a [methyl-Co(III) corrinoid Fe-S protein] + tetrahydrosarcinapterin = a [Co(I) corrinoid Fe-S protein] + 5-methyltetrahydrosarcinapterin

717236, 717755

-

2.3.1.169

CH3-CO-S-CoA + tetrahydrosarcinapterin + H2O = CH3-tetrahydrosarcinapterin + CO2 + H+ + electron

390465, 390474

-

2.1.1.245

CH3-H4SPt + cob(I)amide-protein + H+ = H4SPt + CH3-cob(III)amide-protein

-

2.1.1.86

5-methyl-5,6,7,8-tetrahydrosarcinapterin + coenzyme M = 5,6,7,8-tetrahydrosarcinapterin + methyl-coenzyme M

-

2.3.1.169

CH3-tetrahydrosarcinapterin + CO + HS-CoA = CH3-CO-S-CoA + tetrahydrosarcinapterin

390465

-

3.1.2.1

H2 + CO2 + CH3-H4SPt + CoASH = acetyl-CoA + H4SPt + H2O

-

14.7

-

pH 7.6, 25Â°C

717236

2.1.1.245

0.002

-

pH 7.6, 25Â°C

717236

94491

7718564

Substrate and accessory protein requirements and thermodynamics of acetyl-CoA synthesis and cleavage in Methanosarcina barkeri

1995

Grahame, D.A.; de Moll, E.

Biochemistry

34

4617-4624

390465

8399227

Substrate and cofactor reactivity of a carbon monoxide dehydrogenase-corrinoid enzyme complex: stepwise reduction of iron-sulfur and corrinoid centers, the corrinoid Co2+/1+ redox midpoint potential, and overall synthesis of acetyl-CoA

1993

Grahame, D.A.

Biochemistry

32

10786-10793

390474

1939246

Catalysis of acetyl-CoA cleavage and tetrahydrosarcinapterin methylation by a carbon monoxide dehydrogenase-corrinoid enzyme complex

1991

Grahame, D.A.

J. Biol. Chem.

266

22227-22233

717236

10231523

Mechanism of transfer of the methyl group from (6S)-methyltetrahydrofolate to the corrinoid/iron-sulfur protein catalyzed by the methyltransferase from Clostridium thermoaceticum: a key step in the Wood-Ljungdahl pathway of acetyl-CoA synthesis

1999

Seravalli, J.; Zhao, S.; Ragsdale, S.W.

Biochemistry

38

5728-5735

717755

8626532

Partial reactions catalyzed by protein components of the acetyl-CoA decarbonylase synthase enzyme complex from Methanosarcina barkeri

1996

Grahame, D.; DeMoll, E.

J. Biol. Chem.

271

8352-8358

-

Ligand tetrahydrosarcinapterin

Basic Ligand Information

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

In Vivo Product in Enzyme-catalyzed Reactions (3 results)

Substrate in Enzyme-catalyzed Reactions (3 results)

Product in Enzyme-catalyzed Reactions (6 results)

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (1 result)

K_M Value (1 result)

References & Links

Literature References (5)

Links to other databases for tetrahydrosarcinapterin

Ligand tetrahydrosarcinapterin

Basic Ligand Information

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

In Vivo Product in Enzyme-catalyzed Reactions (3 results)

Substrate in Enzyme-catalyzed Reactions (3 results)

Product in Enzyme-catalyzed Reactions (6 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

KM Value (1 result)

References & Links

Literature References (5)

Links to other databases for tetrahydrosarcinapterin

k_cat Value (Turnover Number) (1 result)

K_M Value (1 result)