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Information on EC 1.8.5.7 - glutathionyl-hydroquinone reductase

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IUBMB Comments
This type of enzymes, which are found in bacteria, halobacteria, fungi, and plants, catalyse the glutathione-dependent reduction of glutathionyl-hydroquinones. The enzyme from the bacterium Sphingobium chlorophenolicum can act on halogenated substrates such as 2,6-dichloro-3-(glutathione-S-yl)-hydroquinone and 2,3,5-trichloro-6-(glutathione-S-yl)-hydroquinone. Substrates for these enzymes are often formed spontaneously by interaction of benzoquinones with glutathione.
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
ECM4, GHR1, glutathionyl-hydroquinone lyase, glutathionyl-hydroquinone reductase, pcpF, yqjG, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
glutathione + 2-(glutathione-S-yl)-hydroquinone = glutathione disulfide + hydroquinone
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PATHWAY SOURCE
PATHWAYS
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