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Information on EC 1.8.4.5 - methionine-S-oxide reductase

for references in articles please use BRENDA:EC1.8.4.5

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transferred to EC 1.8.4.13 and EC 1.8.4.14
IUBMB Comments

In the reverse reaction, dithiothreitol can replace reduced thioredoxin, and other methyl sulfoxides can replace methionine sulfoxide.

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-methionine + thioredoxin disulfide + H2O = L-methionine S-oxide + thioredoxin
show the reaction diagram
ping-pong mechanism with sulfenic acid intermediate
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