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Information on EC 1.8.4.14 - L-methionine (R)-S-oxide reductase

for references in articles please use BRENDA:EC1.8.4.14

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IUBMB Comments

Requires NADPH. Unlike EC 1.8.4.12, peptide-methionine (R)-S-oxide reductase, this enzyme cannot use peptide-bound methionine (R)-S-oxide as a substrate . Differs from EC 1.8.4.13, L-methionine (S)-S-oxide in that L-methionine (S)-S-oxide is not a substrate.

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea

Synonyms
tafrmsr, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-methionine + thioredoxin disulfide + H2O = L-methionine (R)-S-oxide + thioredoxin
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
Highest Expressing Human Cell Lines
Cell Line Links Gene Links