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Information on EC 1.8.4.2 - protein-disulfide reductase (glutathione)

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EC Tree
IUBMB Comments
Reduces insulin and some other proteins.
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This record set is specific for:
UNIPROT: P0C2B2
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Synonyms
glutathione-insulin transhydrogenase, whib1, mif-2, dsba2, dsba1, thiol disulfide oxidoreductase, grxs12, insulin reductase, gsh-insulin transhydrogenase, thiol:protein-disulfide oxidoreductase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
glutathione-insulin transhydrogenase
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glutathione-protein disulfide oxidoreductase
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GSH-insulin transhydrogenase
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insulin reductase
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protein disulfide reductase (glutathione)
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protein disulfide transhydrogenase
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protein-disulfide interchange enzyme
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protein-disulfide isomerase/oxidoreductase
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reductase, protein disulfide (glutathione)
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thiol-protein disulphide oxidoreductase
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thiol:protein-disulfide oxidoreductase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
redox reaction
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oxidation
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reduction
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PATHWAY SOURCE
PATHWAYS
SYSTEMATIC NAME
IUBMB Comments
glutathione:protein-disulfide oxidoreductase
Reduces insulin and some other proteins.
CAS REGISTRY NUMBER
COMMENTARY hide
9082-53-5
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
DsbA homologous
SwissProt
Manually annotated by BRENDA team
DsbA homologous
SwissProt
Manually annotated by BRENDA team
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
DSBA_PSEAE
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
211
0
23375
Swiss-Prot
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Fabianek, R.A.; Hennecke, H.; Thony-Meyer, L.
Periplasmic protein thiol:disulfide oxidoreductases of Escherichia coli
FEMS Microbiol. Rev.
24
303-316
2000
Dickeya chrysanthemi, Dickeya chrysanthemi DsbA homologous, Escherichia coli, Haemophilus influenzae, Haemophilus influenzae DsbA homologous, Klebsiella sp., Klebsiella sp. DsbA homologous, Legionella pneumophila (P50024), Legionella pneumophila DsbA homologous (P50024), Lelliottia amnigena (Q9XDP0), Lelliottia amnigena DsbA homologous (Q9XDP0), Pectobacterium carotovorum, Pectobacterium carotovorum DsbA homologous, Pseudomonas aeruginosa (P0C2B2), Pseudomonas aeruginosa DsbA homologous (P0C2B2), Pseudomonas syringae (O52376), Pseudomonas syringae DsbA homologous (O52376), Salmonella enterica subsp. enterica serovar Enteritidis, Salmonella enterica subsp. enterica serovar Enteritidis DsbA homologous, Salmonella enterica subsp. enterica serovar Typhimurium, Salmonella enterica subsp. enterica serovar Typhimurium DsbA homologous, Shigella flexneri, Shigella flexneri DsbA homologous, Vibrio cholerae serotype O1, Vibrio cholerae serotype O1 DsbA homologous, Yersinia pestis, Yersinia pestis DsbA homologous
Manually annotated by BRENDA team