Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 1.8.1.8 - protein-disulfide reductase and Organism(s) Mus musculus and UniProt Accession Q9DC23

for references in articles please use BRENDA:EC1.8.1.8
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
Specify your search results
Select one or more organisms in this record: ?
This record set is specific for:
Mus musculus
UNIPROT: Q9DC23 not found.
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
The taxonomic range for the selected organisms is: Mus musculus
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
glutaredoxin, disulfide reductase, protein disulfide reductase, pdi reductase, hvtrxh2, protein-disulfide reductase, pfpdo, erp16, phdsb, ma3736, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
protein disulfide reductase
-
disulfide reductase
-
-
-
-
insulin-glutathione transhydrogenase
-
-
-
-
NAD(P)H:protein-disulfide oxidoreductase
-
-
-
-
protein disulfide reductase
-
-
-
-
protein-disulfide reductase (NAD(P)H)
-
-
-
-
reductase, protein disulfide
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
redox reaction
-
-
-
-
oxidation
-
-
-
-
reduction
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
protein-dithiol:NAD(P)+ oxidoreductase
-
CAS REGISTRY NUMBER
COMMENTARY hide
9029-19-0
-
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
thioredoxin
the enzyme contains six thioredoxin domains
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
UniProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
metabolism
protein disulfide reductase ERdj5 mediates endoplasmic reticulum-associated degradation in concert with EDEM1
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
DJC10_MOUSE
793
0
90583
Swiss-Prot
-
CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
sitting drop vapor diffusion method, using 10% (w/v) PEG 8000, 100 mM HEPES (pH 7.5), and 8 mM cystin at 20°C
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
Superdex 200 gel filtration
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli and in HEK-293 cells
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hagiwara, M.; Maegawa, K.; Suzuki, M.; Ushioda, R.; Araki, K.; Matsumoto, Y.; Hoseki, J.; Nagata, K.; Inaba, K.
Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj5
Mol. Cell
41
432-444
2011
Mus musculus (Q9DC23)
Manually annotated by BRENDA team