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3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) deficiency
Immunoextraction of lipoamide dehydrogenase from cultured skin fibroblasts in patients with combined alpha-ketoacid dehydrogenase deficiency.
Acidosis
Deficiency of dihydrolipoamide dehydrogenase due to two mutant alleles (E340K and G101del). Analysis of a family and prenatal testing.
Acidosis, Lactic
A defect in branched-chain amino acid metabolism in a patient with congenital lactic acidosis due to dihydrolipoyl dehydrogenase deficiency.
Acidosis, Lactic
Congenital lactic acidosis, alpha-ketoglutaric aciduria and variant form of maple syrup urine disease due to a single enzyme defect: dihydrolipoyl dehydrogenase deficiency.
Acidosis, Lactic
Deficiency of dihydrolipoyl dehydrogenase (a component of the pyruvate and alpha-ketoglutarate dehydrogenase complexes): a cause of congenital chronic lactic acidosis in infancy.
Acidosis, Lactic
Inhibition of in vitro CO2 production and lipid synthesis by 2-hydroxybutyric acid in rat brain.
Acidosis, Lactic
Leigh disease with deficiency of lipoamide dehydrogenase: treatment failure with dichloroacetate.
Acidosis, Lactic
Lipoamide dehydrogenase deficiency with primary lactic acidosis: favorable response to treatment with oral lipoic acid.
Acidosis, Lactic
Novel mutations in a boy with dihydrolipoamide dehydrogenase deficiency.
Acidosis, Lactic
Pyruvate dehydrogenase subcomplex with lipoamide dehydrogenase deficiency in a patient with lactic acidosis and branched chain ketoaciduria.
Alzheimer Disease
A metabolic signature for long life in the Caenorhabditis elegans Mit mutants.
Alzheimer Disease
An immunochemical study of the pyruvate dehydrogenase deficit in Alzheimer's disease brain.
Alzheimer Disease
Association of the dihydrolipoamide dehydrogenase gene with Alzheimer's disease in an Ashkenazi Jewish population.
Alzheimer Disease
Brain protein and alpha-ketoglutarate dehydrogenase complex activity in Alzheimer's disease.
Alzheimer Disease
Dihydrolipoamide dehydrogenase suppression induces human tau phosphorylation by increasing whole body glucose levels in a C. elegans model of Alzheimer's Disease.
Alzheimer Disease
Suppression of a core metabolic enzyme dihydrolipoamide dehydrogenase (dld) protects against amyloid beta toxicity in C. elegans model of Alzheimer's disease.
Alzheimer Disease
Testing for linkage and association across the dihydrolipoyl dehydrogenase gene region with Alzheimer's disease in three sample populations.
Angiomyolipoma
Nicotinamide adenine dinucleotide staining immediately following radio frequency ablation of renal tumors-is a positive stain synonymous with ablative failure?
Aphasia
The evolution and pathology of frontotemporal dementia.
Aphasia, Primary Progressive
Clinical, neuroimaging, and pathologic features of progressive nonfluent aphasia.
Aphasia, Primary Progressive
Histopathological changes underlying frontotemporal lobar degeneration with clinicopathological correlation.
Ataxia
An investigation of pyruvate metabolism in patients with cerebellar and spinocerebellar degeneration.
Ataxia
Clinical correlations of partial deficiency of lipoamide dehydrogenase.
Ataxia
Evidence for a primary defect of lipoamide dehydrogenase in Friedreich's ataxia.
Ataxia
Leigh syndrome due to compound heterozygosity of dihydrolipoamide dehydrogenase gene mutations. Description of the first E3 splice site mutation.
Ataxia
Lipoamide dehydrogenase: rapid heat inactivation in platelets of patients with recessively inherited ataxia.
Ataxia
Preclinical diagnosis and carrier detection in ataxia associated with abnormalities of lipoamide dehydrogenase.
Ataxia
Pyruvate dehydrogenase, lipoamide dehydrogenase and citrate synthase activity in fibroblasts from patients with Friedreich's and Charlevoix-Saguenay ataxia.
Ataxia Telangiectasia
MicroRNA-361-5p slows down gliomas development through regulating UBR5 to elevate ATMIN protein expression.
Atherosclerosis
Inherited depression of arterial lipoamide dehydrogenase activity associated with susceptibility to atherosclerosis in pigeons.
Autoimmune Pancreatitis
Helicobacter pylori and pancreatic diseases.
Brain Diseases
Leigh syndrome in a girl with a novel DLD mutation causing E3 deficiency.
Brain Infarction
Mitochondrial Dihydrolipoamide Dehydrogenase is Upregulated in Response to Intermittent Hypoxic Preconditioning.
Brain Injuries
Mitochondrial Dihydrolipoamide Dehydrogenase is Upregulated in Response to Intermittent Hypoxic Preconditioning.
Breast Neoplasms
Proteome analysis of schizophrenia patients Wernicke's area reveals an energy metabolism dysregulation.
Breast Neoplasms
Use of cytokeratin 8 immunohistochemistry for assessing cell death after radiofrequency ablation of breast cancers.
Carcinoma
Nicotinamide adenine dinucleotide staining immediately following radio frequency ablation of renal tumors-is a positive stain synonymous with ablative failure?
Carcinoma, Adenoid Cystic
[Multiple trichoepitheliomas, cylindromas and milia. An entity]
Carcinoma, Non-Small-Cell Lung
UBR5 inhibits the radiosensitivity of non-small cell lung cancer cells via the activation of the PI3K/AKT pathway.
Carcinoma, Renal Cell
Interaction of alpha-lipoic acid enantiomers and homologues with the enzyme components of the mammalian pyruvate dehydrogenase complex.
Carcinoma, Renal Cell
Nicotinamide adenine dinucleotide staining immediately following radio frequency ablation of renal tumors-is a positive stain synonymous with ablative failure?
Chagas Disease
Cloning, sequencing and functional expression of dihydrolipoamide dehydrogenase from the human pathogen Trypanosoma cruzi.
Chagas Disease
Inactivation of Trypanosoma cruzi dihydrolipoamide dehydrogenase by leukocyte myeloperoxidase systems: role of hypochloride and nitrite related radicals.
Chagas Disease
Nitrofuran drugs as common subversive substrates of Trypanosoma cruzi lipoamide dehydrogenase and trypanothione reductase.
Chagas Disease
Purification and characterization of lipoamide dehydrogenase from Trypanosoma cruzi.
Colitis
The E3 ubiquitin ligase UBR5 interacts with TTC7A and may be associated with very early onset inflammatory bowel disease.
Cryptorchidism
The effect of cryptorchidism on the quantitative histology, histochemistry and hydrolytic enzyme activity of the rat testis.
Dementia
Dementia lacking distinctive histologic features: a common non-Alzheimer degenerative dementia.
Dementia
Hippocampal sclerosis and ubiquitin-positive inclusions in dementia lacking distinctive histopathology.
Dementia
Selective reduction of soluble tau proteins in sporadic and familial frontotemporal dementias: an international follow-up study.
Diabetes Mellitus, Type 2
Chronic Inhibition of Mitochondrial Dihydrolipoamide Dehydrogenase (DLDH) as an Approach to Managing Diabetic Oxidative Stress.
dihydrolipoyl dehydrogenase deficiency
A decrease in glycine cleavage activity in the liver of a patient with dihydrolipoyl dehydrogenase deficiency.
dihydrolipoyl dehydrogenase deficiency
A defect in branched-chain amino acid metabolism in a patient with congenital lactic acidosis due to dihydrolipoyl dehydrogenase deficiency.
dihydrolipoyl dehydrogenase deficiency
An Updated View on the Molecular Pathomechanisms of Human Dihydrolipoamide Dehydrogenase Deficiency in Light of Novel Crystallographic Evidence.
dihydrolipoyl dehydrogenase deficiency
ATP synthesis in lipoamide dehydrogenase deficiency.
dihydrolipoyl dehydrogenase deficiency
Biochemical and molecular diagnosis of lipoamide dehydrogenase deficiency in a North American Ashkenazi Jewish family.
dihydrolipoyl dehydrogenase deficiency
Challenges in Diagnosing a Metabolic Disorder: Error of Pyruvate Metabolism or Drug Induced?
dihydrolipoyl dehydrogenase deficiency
Chemical diagnosis of dihydrolipoyl dehydrogenase deficiency.
dihydrolipoyl dehydrogenase deficiency
Coexisting hereditary methaemoglobinaemia and heterozygous beta-thalassaemia.
dihydrolipoyl dehydrogenase deficiency
Congenital enzymopenic methaemoglobinaemia. Clinical and biochemical study of a family with three homozygotes.
dihydrolipoyl dehydrogenase deficiency
Congenital lactic acidosis, alpha-ketoglutaric aciduria and variant form of maple syrup urine disease due to a single enzyme defect: dihydrolipoyl dehydrogenase deficiency.
dihydrolipoyl dehydrogenase deficiency
Congenital lacticacidemia caused by lipoamide dehydrogenase deficiency with favorable outcome.
dihydrolipoyl dehydrogenase deficiency
Congenital methaemoglobinaemia due to NADH methaemoglobin reductase deficiency: successful treatment with oral riboflavin.
dihydrolipoyl dehydrogenase deficiency
Dihydrolipoamide dehydrogenase deficiency: A still overlooked cause of recurrent acute liver failure and Reye-like syndrome.
dihydrolipoyl dehydrogenase deficiency
Dihydrolipoyl dehydrogenase deficiency: a therapeutic trial with branched-chain amino acid restriction.
dihydrolipoyl dehydrogenase deficiency
Elevated plasma citrulline: look for dihydrolipoamide dehydrogenase deficiency.
dihydrolipoyl dehydrogenase deficiency
HEPNet: A Knowledge Base Model of Human Energy Pool Network for Predicting the Energy Availability Status of an Individual.
dihydrolipoyl dehydrogenase deficiency
Hereditary methemoglobinemia associated with NADH diaphorase deficiency.
dihydrolipoyl dehydrogenase deficiency
Identification of two mutations in a compound heterozygous child with dihydrolipoamide dehydrogenase deficiency.
dihydrolipoyl dehydrogenase deficiency
Lactic acidemia, neurologic deterioration and carbohydrate dependence in a girl with dihydrolipoyl dehydrogenase deficiency.
dihydrolipoyl dehydrogenase deficiency
Leigh syndrome in a girl with a novel DLD mutation causing E3 deficiency.
dihydrolipoyl dehydrogenase deficiency
Lipoamide dehydrogenase activity in lymphocytes.
dihydrolipoyl dehydrogenase deficiency
Lipoamide dehydrogenase deficiency due to a novel mutation in the interface domain.
dihydrolipoyl dehydrogenase deficiency
Lipoamide dehydrogenase deficiency in Ashkenazi Jews: an insertion mutation in the mitochondrial leader sequence.
dihydrolipoyl dehydrogenase deficiency
Lipoamide dehydrogenase deficiency with primary lactic acidosis: favorable response to treatment with oral lipoic acid.
dihydrolipoyl dehydrogenase deficiency
Lipoamide dehydrogenase deficiency.
dihydrolipoyl dehydrogenase deficiency
Lipoamide dehydrogenase deficiency: a new cause for recurrent myoglobinuria.
dihydrolipoyl dehydrogenase deficiency
Lipoamide dehydrogenase deficiency: a newly discovered cause of acute hepatitis in adults.
dihydrolipoyl dehydrogenase deficiency
Liver disease in the Ashkenazi-Jewish lipoamide dehydrogenase deficiency.
dihydrolipoyl dehydrogenase deficiency
Molecular basis of lipoamide dehydrogenase deficiency in Ashkenazi Jews.
dihydrolipoyl dehydrogenase deficiency
Newborn screening for dihydrolipoamide dehydrogenase deficiency: Citrulline as a useful analyte.
dihydrolipoyl dehydrogenase deficiency
Novel mutations in a boy with dihydrolipoamide dehydrogenase deficiency.
dihydrolipoyl dehydrogenase deficiency
Novel mutations in dihydrolipoamide dehydrogenase deficiency in two cousins with borderline-normal PDH complex activity.
dihydrolipoyl dehydrogenase deficiency
Pyruvate dehydrogenase subcomplex with lipoamide dehydrogenase deficiency in a patient with lactic acidosis and branched chain ketoaciduria.
dihydrolipoyl dehydrogenase deficiency
Riboflavin responsive mitochondrial myopathy is a new phenotype of dihydrolipoamide dehydrogenase deficiency. The chaperon-like effect of vitamin B2.
dihydrolipoyl dehydrogenase deficiency
Studies of urinary organic acid profiles of a patient with dihydrolipoyl dehydrogenase deficiency.
dihydrolipoyl dehydrogenase deficiency
The expanding clinical spectrum of mitochondrial diseases.
dihydrolipoyl dehydrogenase deficiency
Underlying molecular alterations in human dihydrolipoamide dehydrogenase deficiency revealed by structural analyses of disease-causing enzyme variants.
dihydrolipoyl dehydrogenase deficiency
[Clinical and genetic analysis of a case of dihydrolipoamide dehydrogenase deficiency caused by novel variant of DLD gene].
dihydrolipoyl dehydrogenase deficiency
[Familial NADH diaphorase deficiency]
dihydrolipoyl dehydrogenase deficiency
[Heterogeneity of leucinosis. Correlations between clinical manifestations, protein tolerance and enzyme deficiency]
dihydrolipoyl dehydrogenase deficiency
[Lipoamide dehydrogenase deficiency]
Endometrial Neoplasms
Proteomic identification of dihydrolipoamide dehydrogenase as a target of autoantibodies in patients with endometrial cancer.
Friedreich Ataxia
An investigation of pyruvate metabolism in patients with cerebellar and spinocerebellar degeneration.
Friedreich Ataxia
Correlation between serum lipoamide dehydrogenase activity and phosphatidylcholine therapy in Friedreich's ataxia.
Friedreich Ataxia
Evidence for a primary defect of lipoamide dehydrogenase in Friedreich's ataxia.
Friedreich Ataxia
Friedreich ataxia. II. Normal kinetics of lipoamide dehydrogenase.
Friedreich Ataxia
Immunoreactive levels of alpha-ketoglutarate dehydrogenase subunits in Friedreich's ataxia and spinocerebellar ataxia type 1.
Friedreich Ataxia
Kinetic evidence for a structural abnormality of lipoamide dehydrogenase in two patients with Friedreich ataxia.
Friedreich Ataxia
Lipoamide dehydrogenase in cultured human skin fibroblasts.
Friedreich Ataxia
Lipoamide dehydrogenase in Friedreich's ataxia fibroblasts.
Friedreich Ataxia
Lipoamide dehydrogenase: rapid heat inactivation in platelets of patients with recessively inherited ataxia.
Friedreich Ataxia
Preclinical diagnosis and carrier detection in ataxia associated with abnormalities of lipoamide dehydrogenase.
Friedreich Ataxia
Pyruvate dehydrogenase, lipoamide dehydrogenase and citrate synthase activity in fibroblasts from patients with Friedreich's and Charlevoix-Saguenay ataxia.
Friedreich Ataxia
Serum and platelet lipoamide dehydrogenase in Friedreich's ataxia.
Frontotemporal Dementia
Histopathological changes underlying frontotemporal lobar degeneration with clinicopathological correlation.
Frontotemporal Dementia
Loss of brain tau defines novel sporadic and familial tauopathies with frontotemporal dementia.
Frontotemporal Dementia
Selective reduction of soluble tau proteins in sporadic and familial frontotemporal dementias: an international follow-up study.
Frontotemporal Dementia
Soluble amyloid beta-protein is increased in frontotemporal dementia with tau gene mutations.
Frontotemporal Dementia
The evolution and pathology of frontotemporal dementia.
Frontotemporal Lobar Degeneration
Dementia lacking distinctive histology (DLDH) revisited.
fumarate hydratase deficiency
The expanding clinical spectrum of mitochondrial diseases.
Genetic Diseases, Inborn
An Updated View on the Molecular Pathomechanisms of Human Dihydrolipoamide Dehydrogenase Deficiency in Light of Novel Crystallographic Evidence.
Genetic Diseases, Inborn
Underlying molecular alterations in human dihydrolipoamide dehydrogenase deficiency revealed by structural analyses of disease-causing enzyme variants.
Glioblastoma
Biomarker discovery: a proteomic approach for brain cancer profiling.
Glioma
MicroRNA-361-5p slows down gliomas development through regulating UBR5 to elevate ATMIN protein expression.
Glucose Intolerance
Friedreich's ataxia 1979: an overview.
Head and Neck Neoplasms
Dihydrolipoamide dehydrogenase regulates cystine deprivation-induced ferroptosis in head and neck cancer.
Hemorrhagic Fever, Crimean
Genetic characterization of Erve virus, a European Nairovirus distantly related to Crimean-Congo hemorrhagic fever virus.
Hemorrhagic Fever, Crimean
Independent inhibition of the polymerase and deubiquitinase activities of the Crimean-Congo Hemorrhagic Fever Virus full-length L-protein.
Hepatic Encephalopathy
The two catalytic components of the 2-oxoglutarate dehydrogenase complex in rat cerebral synaptic and nonsynaptic mitochondria: comparison of the response to in vitro treatment with ammonia, hyperammonemia, and hepatic encephalopathy.
Hepatitis
Lipoamide dehydrogenase deficiency: a newly discovered cause of acute hepatitis in adults.
Hepatitis B
Affibody-displaying bionanocapsules for specific drug delivery to HER2-expressing cancer cells.
Hepatitis B
Characterization of bio-nanocapsule as a transfer vector targeting human hepatocyte carcinoma by disulfide linkage modification.
Hepatitis B
Construction of arginine-rich peptide displaying bionanocapsules.
Hepatitis B
Hepatitis B Virus Core Promoter Double Mutations (A1762T, G1764A) Are Associated with Lower Levels of Serum Dihydrolipoyl Dehydrogenase.
Hepatitis B
In vivo uterine local gene delivery system using TAT-displaying bionanocapsules.
Hepatitis B
Myristoylated PreS1-domain of the hepatitis B virus L-protein mediates specific binding to differentiated hepatocytes.
Hepatitis B
Toleration of amino acid substitutions within hepatitis B virus envelope protein epitopes established by peptide replacement set analysis. II. Region S(122-136).
Hepatitis C
Proteinase 3 and dihydrolipoamide dehydrogenase (E3) are major autoantigens in hepatitis C virus (HCV) infection.
Hyperglycinemia, Nonketotic
Ketogenic diet in early myoclonic encephalopathy due to non ketotic hyperglycinemia.
Hypersensitivity
Disruption of ptLPD1 or ptLPD2, genes that encode isoforms of the plastidial lipoamide dehydrogenase, confers arsenate hypersensitivity in Arabidopsis.
Infections
Anaplasma phagocytophilum Dihydrolipoamide Dehydrogenase 1 Affects Host-Derived Immunopathology during Microbial Colonization.
Infections
Characterization of the dihydrolipoamide dehydrogenase from Streptococcus pneumoniae and its role in pneumococcal infection.
Infections
Energy Metabolism in the Placenta and the Role of Disturbances in the Development of Placental Insufficiency at an Exacerbation of Cytomegalovirus Infection.
Infections
Hepatitis B Virus Core Promoter Double Mutations (A1762T, G1764A) Are Associated with Lower Levels of Serum Dihydrolipoyl Dehydrogenase.
Infections
Late therapeutic intervention with a respiratory syncytial virus L-protein polymerase inhibitor, PC786, on RSV infection in human airway epithelium.
Infections
Lipoamide channel-binding sulfonamides selectively inhibit mycobacterial lipoamide dehydrogenase.
Infections
Pathogenicity patterns of mucormycosis: epidemiology, interaction with immune cells and virulence factors.
Infections
Proteinase 3 and dihydrolipoamide dehydrogenase (E3) are major autoantigens in hepatitis C virus (HCV) infection.
Infertility
[Preliminary proteomics analysis of the total proteins of HL Type cytoplasmic male sterility rice anther]
Influenza, Human
Bunyaviridae RNA polymerases (L-protein) have an N-terminal, influenza-like endonuclease domain, essential for viral cap-dependent transcription.
Intellectual Disability
Congenital enzymopenic methaemoglobinaemia. Clinical and biochemical study of a family with three homozygotes.
Intellectual Disability
Leigh syndrome due to compound heterozygosity of dihydrolipoamide dehydrogenase gene mutations. Description of the first E3 splice site mutation.
Ischemic Stroke
Administration of 5-methoxyindole-2-carboxylic acid that potentially targets mitochondrial dihydrolipoamide dehydrogenase confers cerebral preconditioning against ischemic stroke injury.
Ischemic Stroke
Mitochondrial Dihydrolipoamide Dehydrogenase is Upregulated in Response to Intermittent Hypoxic Preconditioning.
Ketosis
Leigh syndrome in a girl with a novel DLD mutation causing E3 deficiency.
Ketosis
Pyruvate dehydrogenase subcomplex with lipoamide dehydrogenase deficiency in a patient with lactic acidosis and branched chain ketoaciduria.
Kidney Failure, Chronic
Light microscopic study of striated muscle in uremia.
Learning Disabilities
Leigh syndrome in a girl with a novel DLD mutation causing E3 deficiency.
Leigh Disease
Deficiency of pyruvate dehydrogenase complex (PDHC) in Leigh's disease fibroblasts: an abnormality in lipoamide dehydrogenase affecting PDHC activation.
Leigh Disease
Leigh disease with deficiency of lipoamide dehydrogenase: treatment failure with dichloroacetate.
Leigh Disease
Leigh syndrome due to compound heterozygosity of dihydrolipoamide dehydrogenase gene mutations. Description of the first E3 splice site mutation.
Leigh Disease
Leigh syndrome in a girl with a novel DLD mutation causing E3 deficiency.
Leigh Disease
Studies on pyruvate carboxylase, pyruvate decarboxylase and lipoamide dehydrogenase in subacute necrotizing encephalomyelopathy.
Liver Cirrhosis, Biliary
Autoantibody against dihydrolipoamide dehydrogenase, the E3 subunit of the 2-oxoacid dehydrogenase complexes: significance for primary biliary cirrhosis.
Liver Cirrhosis, Biliary
Hepatic portal infiltrates in mice immunized with syngeneic lymphoid cells: connotations for models of autoimmune liver disease.
Liver Cirrhosis, Biliary
Humoral and cellular immune responses to dihydrolipoamide dehydrogenase (E3): lack of specificity for primary biliary cirrhosis.
Liver Diseases
Hepatic portal infiltrates in mice immunized with syngeneic lymphoid cells: connotations for models of autoimmune liver disease.
Liver Diseases
Hepatitis B Virus Core Promoter Double Mutations (A1762T, G1764A) Are Associated with Lower Levels of Serum Dihydrolipoyl Dehydrogenase.
Liver Diseases
Liver disease in the Ashkenazi-Jewish lipoamide dehydrogenase deficiency.
Liver Failure
The two catalytic components of the 2-oxoglutarate dehydrogenase complex in rat cerebral synaptic and nonsynaptic mitochondria: comparison of the response to in vitro treatment with ammonia, hyperammonemia, and hepatic encephalopathy.
Liver Failure, Acute
Dihydrolipoamide dehydrogenase deficiency: A still overlooked cause of recurrent acute liver failure and Reye-like syndrome.
Liver Neoplasms, Experimental
Characteristics of mitochondria isolated by rate zonal centrifugation from normal liver and Novikoff hepatomas.
Lung Injury
Redox imbalance and mitochondrial abnormalities in the diabetic lung.
Lung Neoplasms
UBR5 inhibits the radiosensitivity of non-small cell lung cancer cells via the activation of the PI3K/AKT pathway.
Lymphocytic Choriomeningitis
Metal chelators for the inhibition of the lymphocytic choriomeningitis virus endonuclease domain.
Maple Syrup Urine Disease
Congenital lactic acidosis, alpha-ketoglutaric aciduria and variant form of maple syrup urine disease due to a single enzyme defect: dihydrolipoyl dehydrogenase deficiency.
Maple Syrup Urine Disease
Newborn screening for dihydrolipoamide dehydrogenase deficiency: Citrulline as a useful analyte.
Maple Syrup Urine Disease
Pyruvate dehydrogenase subcomplex with lipoamide dehydrogenase deficiency in a patient with lactic acidosis and branched chain ketoaciduria.
Measles
Oligomerization of the Vesicular Stomatitis Virus Phosphoprotein Is Dispensable for mRNA Synthesis but Facilitates RNA Replication.
Melanoma
Downregulation of dihydrolipoyl dehydrogenase by UVA suppresses melanoma progression via triggering oxidative stress and altering energy metabolism.
Metabolic Diseases
Inhibition of in vitro CO2 production and lipid synthesis by 2-hydroxybutyric acid in rat brain.
Metabolic Diseases
Structural alterations induced by ten disease-causing mutations of human dihydrolipoamide dehydrogenase analyzed by hydrogen/deuterium-exchange mass spectrometry: Implications for the structural basis of E3 deficiency.
Metabolic Syndrome
E4F1 controls a transcriptional program essential for pyruvate dehydrogenase activity.
Methemoglobinemia
Hereditary methemoglobinemia associated with NADH diaphorase deficiency.
Microcephaly
Leigh syndrome due to compound heterozygosity of dihydrolipoamide dehydrogenase gene mutations. Description of the first E3 splice site mutation.
Mitochondrial Diseases
Successful TAT-mediated enzyme replacement therapy in a mouse model of mitochondrial E3 deficiency.
Mitochondrial Diseases
TAT-mediated Delivery of LAD Restores Pyruvate Dehydrogenase Complex Activity in the Mitochondria of Patients with LAD Deficiency.
Mitochondrial Diseases
TAT-mediated delivery of LAD restores pyruvate dehydrogenase complex activity in the mitochondria of patients with LAD deficiency.
Mitochondrial Myopathies
Riboflavin responsive mitochondrial myopathy is a new phenotype of dihydrolipoamide dehydrogenase deficiency. The chaperon-like effect of vitamin B2.
Motor Neuron Disease
Hippocampal sclerosis and ubiquitin-positive inclusions in dementia lacking distinctive histopathology.
Mucormycosis
Pathogenicity patterns of mucormycosis: epidemiology, interaction with immune cells and virulence factors.
Multiple Acyl Coenzyme A Dehydrogenase Deficiency
Inhibition of in vitro CO2 production and lipid synthesis by 2-hydroxybutyric acid in rat brain.
Muscle Hypotonia
Leigh disease with deficiency of lipoamide dehydrogenase: treatment failure with dichloroacetate.
Muscle Spasticity
An investigation of pyruvate metabolism in patients with cerebellar and spinocerebellar degeneration.
Myocarditis
Analysis of mitochondrial antigens reveals inner membrane succinate dehydrogenase flavoprotein subunit as autoantigen to antibodies in anti-M7 sera.
Myoglobinuria
Lipoamide dehydrogenase deficiency: a new cause for recurrent myoglobinuria.
Myoglobinuria
Lipoamide dehydrogenase deficiency: a newly discovered cause of acute hepatitis in adults.
Nairobi Sheep Disease
Genetic characterization of Erve virus, a European Nairovirus distantly related to Crimean-Congo hemorrhagic fever virus.
Neoplasms
Comprehensive Analysis of Somatic Mutations in Colorectal Cancer With Peritoneal Metastasis.
Neoplasms
Dihydrolipoamide dehydrogenase moonlighting activity as a DNA chelating agent.
Neoplasms
Feasibility of induction heating using a sintered MgFe2O4 needle for minimally invasive breast cancer therapy.
Neoplasms
Feasibility study on radiofrequency ablation followed by partial mastectomy for stage I breast cancer patients.
Neoplasms
Histopathological effect of radiofrequency ablation therapy for primary breast cancer, with special reference to changes in cancer cells and stromal structure and a comparison with enzyme histochemistry.
Neoplasms
Identification of a recurrent transforming UBR5-ZNF423 fusion gene in EBV-associated nasopharyngeal carcinoma.
Neoplasms
Independent inhibition of the polymerase and deubiquitinase activities of the Crimean-Congo Hemorrhagic Fever Virus full-length L-protein.
Neoplasms
Minimization of energy transduction confers resistance to phosphine in the rice weevil, Sitophilus oryzae.
Neoplasms
Novel tumor-ablation device for liver tumors utilizing heat energy generated under an alternating magnetic field.
Neoplasms
Overexpression of UBR5 promotes tumor growth in gallbladder cancer via PTEN/PI3K/Akt signal pathway.
Neoplasms
Selective prostate cancer thermal ablation with laser activated gold nanoshells.
Neoplasms
Targeting the Achilles' heel of cancer cells via integrin-mediated delivery of ROS-generating dihydrolipoamide dehydrogenase.
Neoplasms
Targeting ubiquitin protein ligase E3 component N-recognin 5 in cancer cells induces a CD8+ T cell mediated immune response.
Neoplasms
The moonlighting activities of dihydrolipoamide dehydrogenase: Biotechnological and biomedical applications.
Neoplasms
UBR5 inhibits the radiosensitivity of non-small cell lung cancer cells via the activation of the PI3K/AKT pathway.
Neoplasms
UBR5 regulates proliferation and radiosensitivity in human laryngeal carcinoma via the p38/MAPK signaling pathway.
Neoplasms
[Microwave coagulation at different temperatures for hepatocellular carcinoma management: efficacy evaluation by enzyme histochemical staining]
Neoplasms
[Multiple trichoepitheliomas, cylindromas and milia. An entity]
Neuroblastoma
Electron spin resonance studies of the interaction of oxidoreductases with 2,6-dimethoxy-p-quinone and semiquinone.
Neurodegenerative Diseases
Notch-1 immunoexpression is increased in Alzheimer's and Pick's disease.
Obesity
Obesity-mediated regulation of cardiac protein acetylation: parallel analysis of total and acetylated proteins via TMT-tagged mass spectrometry.
Obesity
Pharmacological Blockade of Cannabinoid CB1 Receptors in Diet-Induced Obesity Regulates Mitochondrial Dihydrolipoamide Dehydrogenase in Muscle.
Ovarian Neoplasms
Identification of phosphorylation sites on the E3 ubiquitin ligase UBR5/EDD.
oxoglutarate dehydrogenase (succinyl-transferring) deficiency
A novel mutation in the dihydrolipoamide dehydrogenase E3 subunit gene (DLD) resulting in an atypical form of alpha-ketoglutarate dehydrogenase deficiency.
oxoglutarate dehydrogenase (succinyl-transferring) deficiency
The expanding clinical spectrum of mitochondrial diseases.
Parkinson Disease
Role of lipoamide dehydrogenase and metallothionein on 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced neurotoxicity.
Pick Disease of the Brain
Dementia lacking distinctive histologic features: a common non-Alzheimer degenerative dementia.
Pick Disease of the Brain
[FTLD-U and Pick disease without Pick bodies--a clinical and pathological review]
Pneumococcal Infections
Characterization of the dihydrolipoamide dehydrogenase from Streptococcus pneumoniae and its role in pneumococcal infection.
Polycystic Kidney Diseases
Comprehensive Analysis of Somatic Mutations in Colorectal Cancer With Peritoneal Metastasis.
Polycystic Kidney, Autosomal Recessive
Comprehensive Analysis of Somatic Mutations in Colorectal Cancer With Peritoneal Metastasis.
Propionic Acidemia
Inhibition of in vitro CO2 production and lipid synthesis by 2-hydroxybutyric acid in rat brain.
Psoriasis
[Activity of NADH-2 oxidoreductase: a lipoamide dehydrogenase in red blooc cells of patients with psoriasis]
pyruvate dehydrogenase (acetyl-transferring) deficiency
Pyruvate dehydrogenase E3 binding protein (protein X) deficiency.
pyruvate dehydrogenase (nadp+) deficiency
The genetic heterogeneity of lactic acidosis: occurrence of recognizable inborn errors of metabolism in pediatric population with lactic acidosis.
Pyruvate Dehydrogenase Complex Deficiency Disease
Pyruvate dehydrogenase E3 binding protein (protein X) deficiency.
Pyruvate Dehydrogenase Complex Deficiency Disease
The genetic heterogeneity of lactic acidosis: occurrence of recognizable inborn errors of metabolism in pediatric population with lactic acidosis.
Rabies
Oligomerization of the Vesicular Stomatitis Virus Phosphoprotein Is Dispensable for mRNA Synthesis but Facilitates RNA Replication.
Respiratory Distress Syndrome
[Lung NADH diaphorase activity in rats with respiratory distress syndrome]
Reye Syndrome
Dihydrolipoamide dehydrogenase deficiency: A still overlooked cause of recurrent acute liver failure and Reye-like syndrome.
Riboflavin Deficiency
Radial diffusion assay of lipoamide dehydrogenase and its use to assess riboflavin deficiency.
Sepsis
Characterization of the dihydrolipoamide dehydrogenase from Streptococcus pneumoniae and its role in pneumococcal infection.
Sjogren's Syndrome
Identification of quantitative trait loci for murine autoimmune pancreatitis.
Spinocerebellar Degenerations
An investigation of pyruvate metabolism in patients with cerebellar and spinocerebellar degeneration.
Starvation
HEPNet: A Knowledge Base Model of Human Energy Pool Network for Predicting the Energy Availability Status of an Individual.
Stroke
Administration of 5-methoxyindole-2-carboxylic acid that potentially targets mitochondrial dihydrolipoamide dehydrogenase confers cerebral preconditioning against ischemic stroke injury.
Stroke
Chronic Inhibition of Mitochondrial Dihydrolipoamide Dehydrogenase (DLDH) as an Approach to Managing Diabetic Oxidative Stress.
Stroke
Mitochondrial Dihydrolipoamide Dehydrogenase is Upregulated in Response to Intermittent Hypoxic Preconditioning.
Tauopathies
Loss of brain tau defines novel sporadic and familial tauopathies with frontotemporal dementia.
Tauopathies
Selective reduction of soluble tau proteins in sporadic and familial frontotemporal dementias: an international follow-up study.
Tuberculosis
Catalysis of diaphorase reactions by Mycobacterium tuberculosis lipoamide dehydrogenase occurs at the EH4 level.
Tuberculosis
Characterization of a new member of the flavoprotein disulfide reductase family of enzymes from Mycobacterium tuberculosis.
Tuberculosis
Crystal structure and functional analysis of lipoamide dehydrogenase from Mycobacterium tuberculosis.
Tuberculosis
Dihydrolipoamide dehydrogenase-Lpd (Rv0462)-specific T cell recall responses are higher in healthy household contacts of TB: a novel immunodominant antigen from M. tuberculosis.
Tuberculosis
Lipoamide channel-binding sulfonamides selectively inhibit mycobacterial lipoamide dehydrogenase.
Tuberculosis
Lipoamide dehydrogenase mediates retention of coronin-1 on BCG vacuoles, leading to arrest in phagosome maturation.
Tuberculosis
Mycobacterium tuberculosis lipoamide dehydrogenase is encoded by Rv0462 and not by the lpdA or lpdB genes.
Tuberculosis
Mycobacterium tuberculosislpdC, Rv0462, induces dendritic cell maturation and Th1 polarization.
Tuberculosis
The lipoamide dehydrogenase from Mycobacterium tuberculosis permits the direct observation of flavin intermediates in catalysis.
Tuberculosis
Virulence of Mycobacterium tuberculosis depends on lipoamide dehydrogenase, a member of three multienzyme complexes.
Uremia
HEPNet: A Knowledge Base Model of Human Energy Pool Network for Predicting the Energy Availability Status of an Individual.
Urinary Bladder Neoplasms
Histochemistry of NADH diaphorase and gamma-glutamyltranspeptidase in rat bladder tumors.
Varicose Veins
Muscle changes in patients with varicose veins.
Vesicular Stomatitis
Chemogenetic ON and OFF switches for RNA virus replication.
Vesicular Stomatitis
RNA- temperature-sensitive mutants of vesicular stomatitis virus: L-protein thermosensitivity accounts for transcriptase restriction of group I mutants.
Vesicular Stomatitis
Structure of a rabies virus polymerase complex from electron cryo-microscopy.
Vesicular Stomatitis
The Methyltransferase Region of Vesicular Stomatitis Virus L Polymerase Is a Target Site for Functional Intramolecular Insertion.
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1.8.1.4 dihydrolipoyl dehydrogenase
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
