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Information on EC 1.3.8.15 - 3-(aryl)acrylate reductase

for references in articles please use BRENDA:EC1.3.8.15

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IUBMB Comments

The enzyme, found in some amino acid-fermenting anaerobic bacteria, participates in the fermentation pathways of L-phenylalanine, L-tyrosine, and L-tryptophan. Unlike EC 1.3.1.31, 2-enoate reductase, this enzyme has minimal activity with crotonate.

The expected taxonomic range for this enzyme is: Clostridium sporogenes

Synonyms
acdA, acyl-CoA dehydrogenase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
3-(1H-indol-3-yl)propanoate + electron-transfer flavoprotein = 3-(indol-3-yl)acrylate + reduced electron-transfer flavoprotein
show the reaction diagram
(3)
-
-
-
3-phenylpropanoate + electron-transfer flavoprotein = trans-cinnamate + reduced electron-transfer flavoprotein
show the reaction diagram
(2)
-
-
-
phloretate + electron-transfer flavoprotein = 4-coumarate + reduced electron-transfer flavoprotein
show the reaction diagram
(1)
-
-
-
PATHWAY SOURCE
PATHWAYS
MetaCyc
L-phenylalanine degradation VI (reductive Stickland reaction), L-tryptophan degradation XIII (reductive Stickland reaction), L-tyrosine degradation V (reductive Stickland reaction)
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