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BRENDA support

Ligand reduced flavodoxin

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Basic Ligand Information

Molecular Structure
Picture of reduced flavodoxin (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
Molfile
C12H11N4O2R
reduced flavodoxin
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Synonyms:
4a,5-reduced flavin, dihydroflavodoxin, flavin hydroquinone, flavodoxin semiquinone, reduced electron-transfer flavoprotein, reduced electron-transferring-flavoprotein, reduced electron-transferring flavoprotein, reduced electron transfer flavoprotein, reduced electron transfer flavoprotein, reduced electron transferring flavoprotein, reduced flavin, reduced flavoprotein, [reduced flavodoxin], [reduced NADH-hemoprotein reductase], [reduced NADPH---hemoprotein reductase], [reduced NADPH-hemoprotein reductase], [reduced NADPH.hemoprotein reductase], [reduced NADPH hemoprotein reductase], [reduced NADPHhemoprotein reductase]

Related pathways

Pathway Source
Pathways
BRENDA
(S)-reticuline biosynthesis, aflatoxin biosynthesis, alanine metabolism, androgen and estrogen metabolism, arachidonate biosynthesis more
MetaCyc
(8E,10E)-dodeca-8,10-dienol biosynthesis, 2-methyl-branched fatty acid beta-oxidation, 7,8-dimethylmenaquinone biosynthesis, 8-amino-7-oxononanoate biosynthesis II, 8-methylmenaquinone biosynthesis more


Show all pahtways known for Show all BRENDA pathways known for reduced flavodoxin

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (439 results)

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EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3-hydroxybenzoate + [reduced NADPH-hemoprotein reductase] + O2 = 3,4-dihydroxybenzoate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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benzylamine + [reduced NADPH-hemoprotein reductase] + O2 = benzylamine N-oxide + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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dihydrochelirubine + [reduced NADPH-hemoprotein reductase] + O2 = 12-hydroxydihydrochelirubine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(S)-N-methylcoclaurine + [reduced NADPH-hemoprotein reductase] + O2 = (S)-3'-hydroxy-N-methylcoclaurine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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vinorine + [reduced NADPH-hemoprotein reductase] + O2 = vomilenine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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15,16-epoxy-syn-pimaradiene + O2 + [reduced NADPH-hemoprotein reductase] = 15,16-epoxy-syn-pimaradien-19-ol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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alpha-humulene + O2 + [reduced NADPH-hemoprotein reductase] = 10-hydroxy-alpha-humulene + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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tryprostatin B + [reduced NADPH-hemoprotein reductase] + O2 = 6-hydroxytryprostatin B + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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fumitremorgin C + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 = 12alpha,13alpha-dihydroxyfumitremorgin C + 2 [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
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dammarenediol-II + [reduced NADPH-hemoprotein reductase] + O2 = protopanaxadiol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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protopanaxadiol + [reduced NADPH-hemoprotein reductase] + O2 = protopanaxatriol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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ent-sandaracopimaradien-3beta-ol + [reduced NADPH-hemoprotein reductase] + O2 = oryzalexin E + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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ent-sandaracopimaradien-3beta-ol + [reduced NADPH-hemoprotein reductase] + O2 = oryzalexin D + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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dihydromonacolin L acid + [reduced NADPH-hemoprotein reductase] + O2 = 3alpha-hydroxy-3,5-dihydromonacolin L acid + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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monacolin L acid + [reduced NADPH-hemoprotein reductase] + O2 = monacolin J acid + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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methyl (2E,6E)-farnesoate + [reduced NADPH-hemoprotein reductase] + O2 = juvenile hormone III + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(2E,6E)-farnesoate + [reduced NADPH-hemoprotein reductase] + O2 = juvenile-hormone-III carboxylate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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dodecanoate + [reduced NADPH-hemoprotein reductase] + O2 = 7-hydroxydodecanoate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(-)-4'-demethyldeoxypodophyllotoxin + [reduced NADPH-hemoprotein reductase] + O2 = (-)-4'-demethylepipodophyllotoxin + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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beta-amyrin + [reduced NADPH-hemoprotein reductase] + O2 = 24-hydroxy-beta-amyrin + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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10-deoxysarpagine + [reduced NADPH-hemoprotein reductase] + O2 = sarpagine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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lithocholate + [reduced NADPH-hemoprotein reductase] + O2 = 6beta-hydroxylithocholate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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8-dimethylallylnaringenin + [reduced NADPH-hemoprotein reductase] + O2 = leachianone G + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(+)-pulegone + [reduced NADPH-hemoprotein reductase] + O2 = (+)-menthofuran + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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abietadiene + [reduced NADPH-hemoprotein reductase] + O2 = abietadienol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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geranylgeraniol + [reduced NADPH-hemoprotein reductase] + O2 = 18-hydroxygeranylgeraniol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(+)-columbianetin + [reduced NADPH-hemoprotein reductase] + O2 = angelicin + acetone + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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L-tryptophan + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 = (E)-indol-3-ylacetaldoxime + 2 [oxidized NADPH-hemoprotein reductase] + CO2 + 3 H2O
show the reaction diagram
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(+)-cis,trans-nepetalactol + 3 [reduced NADPH-hemoprotein reductase] + 3 O2 = 7-deoxyloganetate + 3 [oxidized NADPH-hemoprotein reductase] + 4 H2O
show the reaction diagram
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(S)-1-hydroxy-N-methylcanadine + [reduced NADPH-hemoprotein reductase] + O2 = (13S,14R)-1,13-dihydroxy-N-methylcanadine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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fraxetin + [reduced NADPH-hemoprotein reductase] + O2 = sideretin (reduced form) + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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indole-3-carbonyl nitrile + [reduced NADPH-hemoprotein reductase] + O2 = 4-hydroxyindole-3-carbonyl nitrile + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(S)-N-methylcanadine + [reduced NADPH-hemoprotein reductase] + O2 = (S)-1-hydroxy-N-methylcanadine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine + [reduced NADPH-hemoprotein reductase] + O2 = (13S,14R)-13-O-acetyl-1,8-dihydroxy-N-methylcanadine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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squalene + [reduced NADPH-hemoprotein reductase] + O2 = (3S)-2,3-epoxy-2,3-dihydrosqualene + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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beta-amyrin + [reduced NADPH-hemoprotein reductase] + O2 = 16alpha-hydroxy-beta-amyrin + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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geranylhydroquinone + [reduced NADPH-hemoprotein reductase] + O2 = 3''-hydroxygeranylhydroquinone + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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a C28 steroid + [reduced NADPH-hemoprotein reductase] + O2 = a (22S)-22-hydroxy-C28-steroid + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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tryptamine + O2 + [reduced NADPH-hemoprotein reductase] = serotonin + H2O + [oxidized NADPH-hemoprotein reductase]
show the reaction diagram
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geissoschizine + [reduced NADPH-hemoprotein reductase] + O2 = rhazimal + [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
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norfluorocurarine + [reduced NADPH-hemoprotein reductase] + O2 = 18-hydroxynorfluorocurarine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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strychnine + [reduced NADPH-hemoprotein reductase] + O2 = 10-hydroxystrychnine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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beta-colubrine + [reduced NADPH-hemoprotein reductase] + O2 = 11-demethylbrucine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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10-deacetyl-1-dehydroxybaccatin III + [reduced NADPH-hemoprotein reductase] + O2 = 10-deacetylbaccatin III + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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3'-N-debenzoyl-2'-deoxytaxol + [reduced NADPH-hemoprotein reductase] + O2 = 3'-N-debenzoyltaxol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(S)-4(1-methylpyrrolidin-2-yl)-3-oxobutanoate + [reduced NADPH-hemoprotein reductase] + O2 = ecgonone + [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
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cholesterol + [reduced NADPH-hemoprotein reductase] + O2 = 7alpha-hydroxycholesterol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(24S)-cholest-5-ene-3beta,24-diol + [reduced NADPH-hemoprotein reductase] + O2 = (24S)-cholest-5-ene-3beta,7alpha,24-triol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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a long-chain acyl-[acyl-carrier protein] + reduced flavodoxin + O2 = pimeloyl-[acyl-carrier protein] + an n-alkanal + oxidized flavodoxin + H2O
show the reaction diagram
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12-hydroxyjasmonoyl-L-isoleucine + [reduced NADPH-hemoprotein reductase] + O2 = 12-hydroxy-12-oxojasmonoyl-L-isoleucine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(S)-limonene + [reduced NADPH-hemoprotein reductase] + O2 = (-)-perillyl alcohol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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phenylacetate + [reduced NADPH-hemoprotein reductase] + O2 = (2-hydroxyphenyl)acetate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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quinine + [reduced NADPH-hemoprotein reductase] + O2 = 3-hydroxyquinine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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11-hydroxyferruginol + 3 [reduced NADPH-hemoprotein reductase] + 3 O2 = carnosic acid + 3 [oxidized NADPH-hemoprotein reductase] + 4 H2O
show the reaction diagram
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demethylsuberosin + [reduced NADPH-hemoprotein reductase] + O2 = (+)-marmesin + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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albendazole + [reduced NADPH-hemoprotein reductase] + O2 = 4'-hydroxyalbendazole + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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fenbendazole + [reduced NADPH-hemoprotein reductase] + O2 = hydroxyfenbendazole + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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7-deoxyloganin + [reduced NADPH-hemoprotein reductase] + O2 = loganin + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(6aR,11aR)-3,9-dihydroxypterocarpan + [reduced NADPH-hemoprotein reductase] + O2 = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(+)-germacrene A + 3 [reduced NADPH-hemoprotein reductase] + 3 O2 = germacra-1(10),4,11(13)-trien-12-oate + 3 [oxidized NADPH-hemoprotein reductase] + 4 H2O
show the reaction diagram
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(S)-cis-N-methylcanadine + [reduced NADPH-hemoprotein reductase] + O2 = allocryptopine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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protopine + [reduced NADPH-hemoprotein reductase] + O2 = 6-hydroxyprotopine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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coniferaldehyde + [reduced NADPH-hemoprotein reductase] + O2 = 5-hydroxyconiferaldehyde + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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beta-amyrin + [reduced NADPH-hemoprotein reductase] + O2 = 11alpha-hydroxy-beta-amyrin + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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4'-O-methylnorbelladine + [reduced NADPH-hemoprotein reductase] + O2 = N-demethylnarwedine + [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
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(S)-reticuline + [reduced NADPH-hemoprotein reductase] + O2 = (S)-corytuberine + [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
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2-(L-cystein-S-yl)-2-(1H-indol-3-yl)acetonitrile + [reduced NADPH-hemoprotein reductase] + O2 = camalexin + hydrogen cyanide + CO2 + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2 = salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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cyclo(L-tyrosyl-L-tyrosyl) + [reduced NADPH-hemoprotein reductase] + O2 = mycocyclosin + [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
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tryprostatin A + [reduced NADPH-hemoprotein reductase] + O2 = fumitremorgin C + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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reduced flavodoxin + NADP+ = oxidized flavodoxin + NADPH + H+
show the reaction diagram
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crotonobetainyl-CoA + reduced electron-transfer flavoprotein = gamma-butyrobetainyl-CoA + electron-transfer flavoprotein
show the reaction diagram
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nitrate + reduced flavodoxin = nitrite + oxidized flavodoxin + H2O
show the reaction diagram
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2 S-adenosyl-L-methionine + protoheme + 2 reduced flavodoxin = S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + anaerobilin + Fe2+ + 2 oxidized flavodoxin
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (32 results)

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EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(R)-2-hydroxyglutarate + electron transfer flavoprotein = 2-oxoglutarate + reduced electron transfer flavoprotein
show the reaction diagram
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(19E)-geissoschizine + [oxidized NADPH-hemoprotein reductase] + O2 = polyneuridine aldehyde + [reduced NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
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(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + oxidized flavodoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + reduced flavodoxin
show the reaction diagram
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(2S)-methylsuccinyl-CoA + electron-transfer flavoprotein = 2-methylfumaryl-CoA + reduced electron-transfer flavoprotein
show the reaction diagram
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isovaleryl-CoA + electron-transfer flavoprotein = 3-methylcrotonyl-CoA + reduced electron-transfer flavoprotein
show the reaction diagram
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sarcosine + H2O + electron-transfer flavoprotein = glycine + formaldehyde + reduced electron-transfer flavoprotein
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (1232 results)

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EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ethylbenzene + [reduced NADPH-hemoprotein reductase] + O2 = cis-2,3-dihydroxy-1-ethyl-cyclohexa-4,6-diene + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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3-hydroxybenzoate + [reduced NADPH-hemoprotein reductase] + O2 = 3,4-dihydroxybenzoate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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benzylamine + [reduced NADPH-hemoprotein reductase] + O2 = benzylamine N-oxide + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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dihydrosanguinarine + [reduced NADPH-hemoprotein reductase] + O2 = 10-hydroxydihydrosanguinarine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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dihydrochelirubine + [reduced NADPH-hemoprotein reductase] + O2 = 12-hydroxydihydrochelirubine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(S)-N-methylcoclaurine + [reduced NADPH-hemoprotein reductase] + O2 = (S)-3'-hydroxy-N-methylcoclaurine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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vinorine + [reduced NADPH-hemoprotein reductase] + O2 = vomilenine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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3-hydroxyindolin-2-one + [reduced NADPH-hemoprotein reductase] + O2 = 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + [reduced NADPH-hemoprotein reductase] + O2 = 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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ent-cassa-12,15-diene + [reduced NADPH-hemoprotein reductase] + O2 = 11-(S)-hydroxy-entcassa-12,15-diene + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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alpha-humulene + O2 + [reduced NADPH-hemoprotein reductase] = 10-hydroxy-alpha-humulene + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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tryprostatin B + [reduced NADPH-hemoprotein reductase] + O2 = 6-hydroxytryprostatin B + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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fumitremorgin C + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 = 12alpha,13alpha-dihydroxyfumitremorgin C + 2 [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
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dammarenediol-II + [reduced NADPH-hemoprotein reductase] + O2 = protopanaxadiol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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protopanaxadiol + [reduced NADPH-hemoprotein reductase] + O2 = protopanaxatriol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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ent-sandaracopimaradien-3beta-ol + [reduced NADPH-hemoprotein reductase] + O2 = oryzalexin E + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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monacolin L acid + [reduced NADPH-hemoprotein reductase] + O2 = monacolin J acid + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(2E,6E)-farnesoate + [reduced NADPH-hemoprotein reductase] + O2 = juvenile-hormone-III carboxylate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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2-(or 4-)dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + [reduced NADPH-hemoprotein reductase] + O2 = glyceollin + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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10-deoxysarpagine + [reduced NADPH-hemoprotein reductase] + O2 = sarpagine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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lithocholate + [reduced NADPH-hemoprotein reductase] + O2 = 6beta-hydroxylithocholate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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16alpha-hydroxytestosterone + 3 O2 + 3 reduced flavoprotein = (16alpha,17beta)-estra-1(10),2,4-triene-3,16,17-triol + formate + 4 H2O + 3 oxidized flavoprotein
show the reaction diagram
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8-dimethylallylnaringenin + [reduced NADPH-hemoprotein reductase] + O2 = leachianone G + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(+)-pulegone + [reduced NADPH-hemoprotein reductase] + O2 = (+)-menthofuran + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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abietadiene + [reduced NADPH-hemoprotein reductase] + O2 = abietadienol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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geranylgeraniol + [reduced NADPH-hemoprotein reductase] + O2 = 18-hydroxygeranylgeraniol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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indole + [reduced NADPH-hemoprotein reductase] + O2 = indolin-2-one + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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L-tryptophan + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 = (E)-indol-3-ylacetaldoxime + 2 [oxidized NADPH-hemoprotein reductase] + CO2 + 3 H2O
show the reaction diagram
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(S)-1-hydroxy-N-methylcanadine + [reduced NADPH-hemoprotein reductase] + O2 = (13S,14R)-1,13-dihydroxy-N-methylcanadine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(S)-N-methylcanadine + [reduced NADPH-hemoprotein reductase] + O2 = (S)-1-hydroxy-N-methylcanadine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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squalene + [reduced NADPH-hemoprotein reductase] + O2 = (3S)-2,3-epoxy-2,3-dihydrosqualene + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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beta-amyrin + [reduced NADPH-hemoprotein reductase] + O2 = 16alpha-hydroxy-beta-amyrin + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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C30:0 fatty acid + [reduced NADPH-hemoprotein reductase] + O2 = C30:0 omega-hydroxy fatty acid + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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castasterone + O2 + [reduced NADPH-hemoprotein reductase] = brassinolide + 2 H2O + [oxidized NADPH-hemoprotein reductase]
show the reaction diagram
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tryptamine + O2 + [reduced NADPH-hemoprotein reductase] = serotonin + H2O + [oxidized NADPH-hemoprotein reductase]
show the reaction diagram
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geissoschizine + [reduced NADPH-hemoprotein reductase] + O2 = rhazimal + [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
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norfluorocurarine + [reduced NADPH-hemoprotein reductase] + O2 = 18-hydroxynorfluorocurarine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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strychnine + [reduced NADPH-hemoprotein reductase] + O2 = 10-hydroxystrychnine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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beta-colubrine + [reduced NADPH-hemoprotein reductase] + O2 = 11-demethylbrucine + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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10-deacetyl-1-dehydroxybaccatin III + [reduced NADPH-hemoprotein reductase] + O2 = 10-deacetylbaccatin III + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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3'-N-debenzoyl-2'-deoxytaxol + [reduced NADPH-hemoprotein reductase] + O2 = 3'-N-debenzoyltaxol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(24S)-cholest-5-ene-3beta,24-diol + [reduced NADPH-hemoprotein reductase] + O2 = (24S)-cholest-5-ene-3beta,7alpha,24-triol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(S)-limonene + [reduced NADPH-hemoprotein reductase] + O2 = (-)-perillyl alcohol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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phenylacetate + [reduced NADPH-hemoprotein reductase] + O2 = (2-hydroxyphenyl)acetate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(3S,6E)-nerolidol + [reduced NADPH-hemoprotein reductase] + O2 = (3E)-4,8-dimethylnona-1,3,7-triene + [oxidized NADPH-hemoprotein reductase] + but-3-en-2-one + 2 H2O
show the reaction diagram
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beta-amyrin + [reduced NADPH-hemoprotein reductase] + O2 = maniladiol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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beta-amyrin + [reduced NADPH-hemoprotein reductase] + O2 = daturadiol + [oxidized NADPh-hemoprotein reductase] + H2O
show the reaction diagram
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demethylsuberosin + [reduced NADPH-hemoprotein reductase] + O2 = (+)-marmesin + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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9beta-pimara-7,15-diene + [reduced NADPH-hemoprotein reductase] + O2 = 9beta-pimara-7,15-diene-3beta-ol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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drimenol + [reduced NADPH-hemoprotein reductase] + O2 = drimendiol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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fenbendazole + [reduced NADPH-hemoprotein reductase] + O2 = hydroxyfenbendazole + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(6aR,11aR)-3,9-dihydroxypterocarpan + [reduced NADPH-hemoprotein reductase] + O2 = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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beta-amyrin + [reduced NADPH-hemoprotein reductase] + O2 = 11alpha-hydroxy-beta-amyrin + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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lanosterol + [reduced NADPH-hemoprotein reductase] + O2 = ? + formate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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2-(L-cystein-S-yl)-2-(1H-indol-3-yl)acetonitrile + [reduced NADPH-hemoprotein reductase] + O2 = camalexin + hydrogen cyanide + CO2 + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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cyclo(L-tyrosyl-L-tyrosyl) + [reduced NADPH-hemoprotein reductase] + O2 = mycocyclosin + [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
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reduced flavodoxin + NADP+ = oxidized flavodoxin + NADPH + H+
show the reaction diagram
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6 reduced flavodoxin + N2 + 6 H2O + 6 ATP = 6 oxidized flavodoxin + 2 NH3 + 6 H+ + 6 ADP + 6 phosphate
show the reaction diagram
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reduced flavodoxin + NADP+ = oxidized flavodoxin + NADPH + H+
show the reaction diagram
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crotonobetainyl-CoA + reduced electron-transfer flavoprotein = gamma-butyrobetainyl-CoA + electron-transfer flavoprotein
show the reaction diagram
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tetradecenoyl-CoA + reduced electron transfer flavoprotein = tetradecanoyl-CoA + electron transfer flavoprotein
show the reaction diagram
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reduced flavin + NAD+ = flavin + NADH + H+
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (107 results)

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EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(R)-2-hydroxyglutarate + electron transfer flavoprotein = 2-oxoglutarate + reduced electron transfer flavoprotein
show the reaction diagram
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ethylbenzene + [reduced NADPH-hemoprotein reductase] + O2 = 1-phenylethyl alcohol + 2-phenylethyl alcohol + [reduced NADPH-hemoprotein reductase] + O2
show the reaction diagram
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7-methoxy-4-trifluoromethyl coumarin + H2O + oxidized flavoprotein = ? + O2 + reduced flavoprotein
show the reaction diagram
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(19E)-geissoschizine + [oxidized NADPH-hemoprotein reductase] + O2 = polyneuridine aldehyde + [reduced NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
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(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + oxidized flavodoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + reduced flavodoxin
show the reaction diagram
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gamma-butyrobetainyl-CoA + electron-transfer flavoprotein = crotonobetainyl-CoA + reduced electron-transfer flavoprotein
show the reaction diagram
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palmitoyl-CoA + electron-transfer flavoprotein = (2E)-2-hexadecenoyl-CoA + reduced electron-transfer flavoprotein
show the reaction diagram
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sarcosine + H2O + electron-transfer flavoprotein = glycine + formaldehyde + reduced electron-transfer flavoprotein
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (2 results)

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EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
under anaerobic growth conditions, oxidized ferredoxin (flavodoxin):NADP+ oxidoreductase accepts a hydride from NADPH and transfers the electron to flavodoxin, generating primarily flavodoxin semiquinone. Under anaerobic conditions the decarboxylation of pyruvate is coupled to reduction of flavodoxin, forming the flavodoxin hydroquinone. These reduced forms of flavodoxin bind to inactive cob(II)alamin enzyme, leading to a conformational change that is coupled with dissociation of His759 and protonation of the His759-Asp757-Ser810 triad. Although NADPH oxidation ultimately produces 2 equivalent of flavodoxin semiquinone, only one electron is transferred to methionine synthase during reductive methylation
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chromophore, enzyme I
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (38 results)

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EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1.34
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pH 7.4, 30°C, wild-type flavodoxin from the cyanobacterium Anabaena PCC 7119

KM Value (12 results)

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EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.00734
-
pH 7.4, 30°C, wild-type flavodoxin from the cyanobacterium Anabaena PCC 7119
0.15
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0.033
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canadine synthase in complex with a cytochrome P-450 reductase
0.056
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ionic strength: 50 mM or 200 mM

References & Links

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Links to other databases for reduced flavodoxin

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EXTERNAL LINKS