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Information on EC 1.3.7.5 - phycocyanobilin:ferredoxin oxidoreductase and Organism(s) Nostoc punctiforme and UniProt Accession Q93TM9

for references in articles please use BRENDA:EC1.3.7.5
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IUBMB Comments
Catalyses the four-electron reduction of biliverdin IXalpha (2-electron reduction at both the A and D rings). Reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin. Flavodoxins can be used instead of ferredoxin. The direct conversion of biliverdin IXalpha (BV) to (3Z)-phycocyanolbilin (PCB) in the cyanobacteria Synechocystis sp. PCC 6803, Anabaena sp. PCC7120 and Nostoc punctiforme is in contrast to the proposed pathways of PCB biosynthesis in the red alga Cyanidium caldarium, which involves (3Z)-phycoerythrobilin (PEB) as an intermediate and in the green alga Mesotaenium caldariorum, in which PCB is an isolable intermediate.
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Nostoc punctiforme
UNIPROT: Q93TM9
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The taxonomic range for the selected organisms is: Nostoc punctiforme
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
phycocyanobilin:ferredoxin oxidoreductase, pcya1, ampcyac, ampcyap, 3z-phycocyanobilin:ferredoxin oxidoreductase, phycocyanobilin-ferredoxin oxidoreductase, phycocyanobilin synthase, pcb:ferredoxin oxidoreductase, hy2 protein, ferredoxin-dependent biliverdin reductase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
ferredoxin:3Z-phycocyanobilin oxidoreductase
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oxidoreductase, ferredoxin:3Z-phycocyanobilin
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PcyA
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
redox reaction
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oxidation
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reduction
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SYSTEMATIC NAME
IUBMB Comments
(3Z)-phycocyanobilin:ferredoxin oxidoreductase
Catalyses the four-electron reduction of biliverdin IXalpha (2-electron reduction at both the A and D rings). Reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin. Flavodoxins can be used instead of ferredoxin. The direct conversion of biliverdin IXalpha (BV) to (3Z)-phycocyanolbilin (PCB) in the cyanobacteria Synechocystis sp. PCC 6803, Anabaena sp. PCC7120 and Nostoc punctiforme is in contrast to the proposed pathways of PCB biosynthesis in the red alga Cyanidium caldarium, which involves (3Z)-phycoerythrobilin (PEB) as an intermediate [2] and in the green alga Mesotaenium caldariorum, in which PCB is an isolable intermediate.
CAS REGISTRY NUMBER
COMMENTARY hide
347401-12-1
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(3Z)-phycocyanobilin + oxidized ferredoxin
biliverdin IXa + reduced ferredoxin
show the reaction diagram
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?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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Uniprot
Manually annotated by BRENDA team
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Frankenberg, N.; Mukougawa, K.; Kohchi, T.; Lagarias, J.C.
Functional genomic analysis of the HY2 family of ferredoxin-dependent bilin reductases from oxygenic photosynthetic organisms
Plant Cell
13
965-978
2001
Anabaena sp., Nostoc punctiforme (Q93TM9), Prochlorococcus sp., Prochlorococcus sp. CCMP1378 / MED4, Synechococcus sp., Synechococcus sp. WH8102, Synechocystis sp. (Q55891)
Manually annotated by BRENDA team