Ligand biliverdin

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Basic Ligand Information

Molecular Structure
Picture of biliverdin (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C33H34N4O6
biliverdin
QBUVFDKTZJNUPP-BBROENKCSA-N
Synonyms:
biliverdin-IX-alpha, biliverdin IXalpha


Show all pahtways known for Show all BRENDA pathways known for biliverdin

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (13 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
biliverdin IXalpha + reduced ferredoxin = 15,16-dihydrobiliverdin + oxidized ferredoxin
show the reaction diagram
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biliverdin IXalpha + reduced ferredoxin = (3Z)-phytochromobilin + oxidized ferredoxin
show the reaction diagram
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biliverdin IXalpha + 2 reduced ferredoxin = (3Z)-phycoerythrobilin + 2 oxidized ferredoxin
show the reaction diagram
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biliverdin + ? = bilirubin + ?
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (19 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
heme + 3 AH2 + 3 O2 = biliverdin + Fe2+ + CO + 3 A + 3 H2O
show the reaction diagram
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2 bilirubin + O2 = 2 biliverdin + 2 H2O
show the reaction diagram
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-
15,16-dihydrobiliverdin + oxidized ferrdoxin = biliverdin IXalpha + reduced ferrdoxin
show the reaction diagram
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(3Z)-phytochromobilin + oxidized ferredoxin = biliverdin IXalpha + reduced ferredoxin
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (18 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
biliverdin + O2 = ?
show the reaction diagram
-
biliverdin IXalpha + reduced ferredoxin = 15,16-dihydrobiliverdin + oxidized ferredoxin
show the reaction diagram
-
biliverdin IXalpha + reduced ferredoxin = (3Z)-phytochromobilin + oxidized ferredoxin
show the reaction diagram
-
biliverdin IXalpha + 2 reduced ferredoxin = (3Z)-phycoerythrobilin + 2 oxidized ferredoxin
show the reaction diagram
-
biliverdin + ? = bilirubin + ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (34 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
15,16-dihydrobiliverdin + oxidized ferrdoxin = biliverdin IXalpha + reduced ferrdoxin
show the reaction diagram
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-
(3Z)-phytochromobilin + oxidized ferredoxin = biliverdin IXalpha + reduced ferredoxin
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive inhibitor
-
competitive
-
0.0053 mM, 50% inhibition
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3D Structure of Enzyme-Ligand-Complex (PDB) (4 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (18 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
20
-
-

KM Value (36 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.18
-
-

Ki Value (3 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
4
-
-

References & Links

Links to other databases for biliverdin

ChEBI
PubChem
ChEBI
PubChem