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This bacterial enzyme is involved in the degradation pathways of the alkene 2-methylpropene and the fuel additive tert-butyl methyl ether (MTBE), a widely occurring groundwater contaminant.
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The enzyme appears in viruses and cellular organisms
hydroxyisobutyraldehyde dehydrogenase, mpdC
2-hydroxy-2-methylpropanal + NAD+ + H2O = 2-hydroxy-2-methylpropanoate + NADH + H+
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