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Information on EC 1.2.1.82 - beta-apo-4'-carotenal oxygenase and Organism(s) Neurospora crassa and UniProt Accession Q1K615

for references in articles please use BRENDA:EC1.2.1.82
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IUBMB Comments
Neurosporaxanthin is responsible for the orange color of of Neurospora.
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Neurospora crassa
UNIPROT: Q1K615
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The taxonomic range for the selected organisms is: Neurospora crassa
The enzyme appears in selected viruses and cellular organisms
Synonyms
ylo-1, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SYSTEMATIC NAME
IUBMB Comments
4'-apo-beta,psi-carotenal:NAD+ oxidoreductase
Neurosporaxanthin is responsible for the orange color of of Neurospora.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
apo-4'-lycopenal + NAD+ + H2O
apo-4'-lycopenoic acid + NADH + 2 H+
show the reaction diagram
the in vivo substrate of Ylo-1 is apo-4'-lycopenal rather than its cyclic isomer beta-apo-4'-carotenal
-
-
?
apo-8'-lycopenal + NAD+ + H2O
apo-8'-lycopenoic acid + NADH + 2 H+
show the reaction diagram
-
-
-
?
beta-apo-10'-carotenal + NAD+ + H2O
beta-apo-10'-carotenoic acid + NADH + 2 H+
show the reaction diagram
-
-
-
?
beta-apo-4'-carotenal + NAD+ + H2O
neurosporaxanthin + NADH + 2 H+
show the reaction diagram
-
-
-
?
beta-apo-8'-carotenal + NAD+ + H2O
beta-apo-8'-carotenoic acid + NADH + 2 H+
show the reaction diagram
-
-
-
?
additional information
?
-
no substrates: nonanal, acetaldehyde, benzaldehyde, retinal
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-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
recombinant protein
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
Ylo-1 mRNA is not induced by light
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Estrada, A.F.; Maier, D.; Scherzinger, D.; Avalos, J.; Al-Babili, S.
Novel apocarotenoid intermediates in Neurospora crassa mutants imply a new biosynthetic reaction sequence leading to neurosporaxanthin formation
Fungal Genet. Biol.
45
1497-1505
2008
Neurospora crassa (Q1K615), Neurospora crassa
Manually annotated by BRENDA team
Estrada, A.F.; Youssar, L.; Scherzinger, D.; Al-Babili, S.; Avalos, J.
The ylo-1 gene encodes an aldehyde dehydrogenase responsible for the last reaction in the Neurospora carotenoid pathway
Mol. Microbiol.
69
1207-1220
2008
Neurospora crassa (Q1K615)
Manually annotated by BRENDA team
Sandmann, G.; Takaichi, S.; Fraser, P.
C35-apocarotenoids in the yellow mutant Neurospora crassa YLO
Phytochemistry
69
2886-2890
2008
Neurospora crassa (Q1K615), Neurospora crassa
Manually annotated by BRENDA team