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Information on EC 1.16.1.7 - ferric-chelate reductase (NADH)

for references in articles please use BRENDA:EC1.16.1.7

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IUBMB Comments

Contains FAD. The enzyme catalyses the reduction of bound ferric iron in a variety of iron chelators (siderophores), resulting in the release of ferrous iron. The plant enzyme is Involved in the transport of iron across plant plasma membranes. The enzyme from the bacterium Paracoccus denitrificans can also reduce chromate. cf. EC 1.16.1.9, ferric-chelate reductase (NADPH) and EC 1.16.1.10, ferric-chelate reductase [NAD(P)H].

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Reaction Schemes
2
Fe(II)-siderophore
+
+
=
2
Fe(III)-siderophore
+

Synonyms
ferric-chelate reductase, fe(iii) reductase, fe(iii)-chelate reductase, fe(iii) chelate reductase, ahfro1, ferric reductase oxidase, iron chelate reductase, root fe(iii) reductase, fe3+-chelate reductase, [fe(iii)-edta] reductase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 Fe(II)-siderophore + NAD+ + H+ = 2 Fe(III)-siderophore + NADH
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
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