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Information on EC 1.14.99.54 - lytic cellulose monooxygenase (C1-hydroxylating) and Organism(s) Hypocrea jecorina and UniProt Accession O14405

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IUBMB Comments
This copper-containing enzyme, found in fungi and bacteria, cleaves cellulose in an oxidative manner. The cellulose fragments that are formed contain a D-glucono-1,5-lactone residue at the reducing end, which hydrolyses quickly and spontaneously to the aldonic acid. The electrons are provided in vivo by the cytochrome b domain of EC 1.1.99.18, cellobiose dehydrogenase (acceptor) . Ascorbate can serve as the electron donor in vitro.
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Hypocrea jecorina
UNIPROT: O14405
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
lytic polysaccharide monooxygenase, cbp21, cel61a, aa9 lpmo, cel61b, lpmo9c, lpmo9d, lpmo9a, pagh61b, pagh61a, more
PATHWAY SOURCE
PATHWAYS
SYSTEMATIC NAME
IUBMB Comments
cellulose, hydrogen-donor:oxygen oxidoreductase (D-glucosyl C1-hydroxylating)
This copper-containing enzyme, found in fungi and bacteria, cleaves cellulose in an oxidative manner. The cellulose fragments that are formed contain a D-glucono-1,5-lactone residue at the reducing end, which hydrolyses quickly and spontaneously to the aldonic acid. The electrons are provided in vivo by the cytochrome b domain of EC 1.1.99.18, cellobiose dehydrogenase (acceptor) [1]. Ascorbate can serve as the electron donor in vitro.
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
GUN4_HYPJE
344
0
35511
Swiss-Prot
-