Reference on EC 1.14.20.14 - hapalindole-type alkaloid chlorinase
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hillwig, M.L.; Zhu, Q.; Ittiamornkul, K.; Liu, X.
Discovery of a promiscuous non-heme iron halogenase in ambiguine alkaloid biogenesis implication for an evolvable enzyme family for late-stage halogenation of aliphatic carbons in small molecules
Angew. Chem. Int. Ed. Engl.
55
5780-5784
2016
Fischerella ambigua (A0A076NA91), Hapalosiphon welwitschii (A0A067YX61), Hapalosiphon welwitschii UTEX B 1830 (A0A067YX61)
Zhu, Q.; Liu, X.
Characterization of non-heme iron aliphatic halogenase WelO5* from Hapalosiphon welwitschii IC-52-3 Identification of a minimal protein sequence motif that confers enzymatic chlorination specificity in the biosynthesis
Beilstein J. Org. Chem.
13
1168-1173
2017
Hapalosiphon welwitschii, Hapalosiphon welwitschii (A0A067YX61), Hapalosiphon welwitschii UTEX B 1830 (A0A067YX61), Hapalosiphon welwitschii IC-52-3
Zhu, Q.; Hillwig, M.L.; Doi, Y.; Liu, X.
Aliphatic halogenase enables late-stage C-H functionalization selective synthesis of a brominated Fischerindole alkaloid with enhanced antibacterial activity
ChemBioChem
17
466-470
2016
Hapalosiphon welwitschii (A0A067YX61), Hapalosiphon welwitschii UTEX B 1830 (A0A067YX61)
Liu, X.
In vitro analysis of cyanobacterial nonheme iron-dependent aliphatic halogenases WelO5 and AmbO5
Methods Enzymol.
604
389-404
2018
Hapalosiphon welwitschii (A0A067YX61), Fischerella ambigua (A0A1L1YPD7), Fischerella ambigua UTEX 1903 (A0A1L1YPD7), Hapalosiphon welwitschii UTEX B 1830 (A0A067YX61)
Hillwig, M.L.; Liu, X.
A new family of iron-dependent halogenases acts on freestanding substrates
Nat. Chem. Biol.
10
921-923
2014
Hapalosiphon welwitschii (A0A067YX61), Hapalosiphon welwitschii UTEX B 1830 (A0A067YX61)
Mitchell, A.J.; Zhu, Q.; Maggiolo, A.O.; Ananth, N.R.; Hillwig, M.L.; Liu, X.; Boal, A.K.
Structural basis for halogenation by iron- and 2-oxo-glutarate-dependent enzyme WelO5
Nat. Chem. Biol.
12
636-640
2016
Hapalosiphon welwitschii (A0A067YX61), Hapalosiphon welwitschii UTEX B 1830 (A0A067YX61)
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