Information on EC 220.127.116.11 - 4-hydroxyphenylacetate 1-monooxygenasefor references in articles please use BRENDA:EC18.104.22.168
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A flavoprotein (FAD). Also acts on 4-hydroxyhydratropate (forming 2-methylhomogentisate) and on 4-hydroxyphenoxyacetate (forming hydroquinone and glycolate).
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The enzyme appears in viruses and cellular organisms
4-HPA 1-hydroxylase, 4-hydroxyphenylacetate 1-hydroxylase, 4-hydroxyphenylacetic 1-hydroxylase, oxygenase, 4-hydroxyphenylacetate 1-mono-, more
4-hydroxyphenylacetate + NAD(P)H + H+ + O2 = homogentisate + NAD(P)+ + H2O
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