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Information on EC - L-tyrosine peroxygenase

for references in articles please use BRENDA:EC1.11.2.6
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EC Tree
     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.2 Peroxygenases
       L-tyrosine peroxygenase
IUBMB Comments
The enzyme from the bacterium Streptomyces lincolnensis participates in the biosynthesis of the antibiotic lincomycin A, while that from Streptomyces refuineus is involved in anthramycin biosynthesis. The enzyme, which contains a heme b cofactor, is rapidly inactivated in the presence of hydrogen peroxide, but the presence of L-tyrosine protects it. cf. EC, 3-methyl-L-tyrosine peroxygenase.
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Word Map
The expected taxonomic range for this enzyme is: Streptomyces
Reaction Schemes
lmbb2, l-tyrosine 3-hydroxylase, more
L-tyrosine + H2O2 = L-dopa + H2O
show the reaction diagram
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