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IUBMB CommentsThe product decarboxylates spontaneously to yield 4-methyl-2-oxopentanoate.
The enzyme appears in selected viruses and cellular organisms
Synonyms
3-isopropylmalate dehydrogenase, ipmdh, beta-isopropylmalate dehydrogenase, isopropylmalate dehydrogenase, ipmdh2, ipmdh3, sbipmdh, ipmdh1, beta-ipm dehydrogenase, soipmdh,
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2-hydroxy-4-methyl-3-carboxyvalerate:NAD+ oxidoreductase
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2R,3S-isopropylmalate:NAD+ oxidoreductase (decaboxylating)
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3-IPM dehydrogenase
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beta-IPM dehydrogenase
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beta-isopropylmalate dehydrogenase
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beta-isopropylmalic enzyme
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dehydrogenase, 3-isopropylmalate
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isopropylmalate dehydrogenase
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threo-Ds-3-isopropylmalate dehydrogenase
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(2R,3S)-3-isopropylmalate:NAD+ oxidoreductase
The product decarboxylates spontaneously to yield 4-methyl-2-oxopentanoate.
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1.1.1.85 3-isopropylmalate dehydrogenase
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