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IUBMB CommentsForms part of the fatty acid synthase system in plants. Can be separated from EC 1.1.1.100, 3-oxoacyl-[acyl-carrier-protein] reductase.
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
3-oxoacyl-[acyl carrier protein] (reduced nicotinamide adenine dinucleotide) reductase, more
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3-oxoacyl-[acyl carrier protein] (reduced nicotinamide adenine dinucleotide) reductase
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a (3R)-3-hydroxyacyl-[acyl-carrier protein] + NAD+ = a 3-oxoacyl-[acyl-carrier protein] + NADH + H+
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(3R)-3-hydroxyacyl-[acyl-carrier protein]:NAD+ oxidoreductase
Forms part of the fatty acid synthase system in plants. Can be separated from EC 1.1.1.100, 3-oxoacyl-[acyl-carrier-protein] reductase.
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acetoacetyl-CoA + NADH
3-hydroxybutanoyl-CoA + NAD+
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Substrates: -
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acetoacetyl-N-acetylcysteamine + NADH
3-hydroxybutanoyl-N-acetylcysteamine + NAD+
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Substrates: very poor substrate
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acetoacetyl-[acyl-carrier protein] + NADH
3-hydroxybutanoyl-[acyl-carrier protein] + NAD+
acetoacetyl-[acyl-carrier protein] + NADH
3-hydroxybutanoyl-[acyl-carrier protein] + NAD+
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acetoacetyl-[acyl-carrier protein] + NADH
3-hydroxybutanoyl-[acyl-carrier protein] + NAD+
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Substrates: component of fatty acid synthetase system
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acetoacetyl-[acyl-carrier protein] + NADH
3-hydroxybutanoyl-[acyl-carrier protein] + NAD+
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Substrates: component of fatty acid synthetase system
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6.2
acetoacetyl N-acetyl-cysteamide
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0.155
acetoacetyl-CoA
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0.00965
acetoacetyl-[acyl-carrier protein]
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0.0098
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12000 x g precipitate of homogenate
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avocado
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brenda
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brenda
Highest Expressing Human Cell Lines
Cell Line Links
Gene Links
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FABG4_MYCTU
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
454
0
46830
Swiss-Prot
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168000
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sucrose density gradient centrifugation
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-20°C, 50 mM phosphate buffer, pH 7.0, 10% glycerol, stable for two weeks
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Caughey, I.; Kekwick, R.G.O.
The characteristics of some components of the fatty acid synthetase system in the plastids from the mesocarp of avocado (Persea americana) fruit
Eur. J. Biochem.
123
553-561
1982
Persea americana
brenda
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