2.4.1.B77: alpha-(1->2) branching sucrase
This is an abbreviated version!
For detailed information about alpha-(1->2) branching sucrase, go to the full flat file.
Word Map on EC 2.4.1.B77
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2.4.1.B77
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mesenteroides
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leuconostoc
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alpha-1,2
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dextrans
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u-shape
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glucansucrases
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gorge
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transglucosylation
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dextransucrase
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transglucosidase
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regiospecific
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synthesis
- 2.4.1.B77
-
mesenteroides
-
leuconostoc
-
alpha-1,2
- dextrans
-
u-shape
- glucansucrases
-
gorge
-
transglucosylation
- dextransucrase
- transglucosidase
-
regiospecific
- synthesis
Reaction
Synonyms
BRS-A, DSR-E
ECTree
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Engineering
Engineering on EC 2.4.1.B77 - alpha-(1->2) branching sucrase
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additional information
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engineering of truncated variant DELTAN123-GBD-CD2 for flavonoid glucoside diversification. Mutantions at residues W2135, F2136, F2163 and L2166 lead to improved promiscuity towards flavonoids including quercetin, luteolin, apigenin, morin, chrysin and naringenin
additional information
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large-scale molecular dynamics simulations on truncated variant DELTAN123-GB-CD2 derived from the bifunctional DSR-E reveal a cooperativity of low frequency twisting, bending and wobbling modes leading to the movement of two blocks formed respectively by domains A and C and domains IV and V, and connected via the domain B which forms a flexible structural hinge. The catalytic pocket is surrounded by highly flexible loops that may play a key role in the acceptor promiscuity of DELTAN123-GBD-CD2
additional information
Leuconostoc citreum NRRL B-1299
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large-scale molecular dynamics simulations on truncated variant DELTAN123-GB-CD2 derived from the bifunctional DSR-E reveal a cooperativity of low frequency twisting, bending and wobbling modes leading to the movement of two blocks formed respectively by domains A and C and domains IV and V, and connected via the domain B which forms a flexible structural hinge. The catalytic pocket is surrounded by highly flexible loops that may play a key role in the acceptor promiscuity of DELTAN123-GBD-CD2
-
additional information
Leuconostoc citreum NRRL B-1299
-
engineering of truncated variant DELTAN123-GBD-CD2 for flavonoid glucoside diversification. Mutantions at residues W2135, F2136, F2163 and L2166 lead to improved promiscuity towards flavonoids including quercetin, luteolin, apigenin, morin, chrysin and naringenin
-