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2.1.1.309: 18S rRNA (guanine1575-N7)-methyltransferase

This is an abbreviated version!
For detailed information about 18S rRNA (guanine1575-N7)-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.309

Reaction

S-adenosyl-L-methionine
+
guanine1575 in 18S rRNA
=
S-adenosyl-L-homocysteine
 +
N7-methylguanine1575 in 18S rRNA

Synonyms

18S rRNA methyltransferase, BUD23, rRNA methyltransferase Bud23, WBSCR22, WBSCR22-TRMT112

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.309 18S rRNA (guanine1575-N7)-methyltransferase

Activating Compound

Activating Compound on EC 2.1.1.309 - 18S rRNA (guanine1575-N7)-methyltransferase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
TRM112
-
Trm112 is a small zinc finger protein of 15 kDa which acts as a coactivator of several class I S-adenosyl-L-methionine (SAM)-dependent MTases. Trm112 interacts directly with Bud23 in vitro and that it is absolutely required for Bud23 stability in vivo. Trm112 increases the solubility of Bud23
-
TRMT112
a multifunctional methyltransferase subunit TRM112-like protein with methyltransferase activity, it participates both in methylation of protein and tRNA species. TRMT112 is required for WBSCR22 metabolic stability
-