1.6.1.1: NAD(P)+ transhydrogenase (Si-specific)

This is an abbreviated version!
For detailed information about NAD(P)+ transhydrogenase (Si-specific), go to the full flat file.

Reaction

Synonyms

energy-independent soluble pyridine nucleotide transhydrogenase, H+-thase, NAD transhydrogenase, NAD(P) transhydrogenase, NAD(P)(+) transhydrogenase [B-specific], NADH transhydrogenase, NADH-NADP-transhydrogenase, NADPH-NAD oxidoreductase, NADPH-NAD transhydrogenase, NADPH:NAD+ transhydrogenase, nicotinamide adenine dinucleotide (phosphate) transhydrogenase, nicotinamide nucleotide transhydrogenase, NNT, non-energy-linked transhydrogenase, pyridine nucleotide transferase, pyridine nucleotide transhydrogenase, soluble pyridine nucleotide transhydrogenase, soluble transhydrogenase, STH, SthA, transhydrogenase, transhydrogenase, nicotinamide adenine dinucleotide (phosphate), UdhA

ECTree

     1 Oxidoreductases

         1.6 Acting on NADH or NADPH

             1.6.1 With NAD⁺ or NADP⁺ as acceptor

                1.6.1.1 NAD(P)+ transhydrogenase (Si-specific)

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Results	in table
19	Activating Compound
5881	AA Sequence
3	Application
2	CAS Registry Number
4	Cloned(Commentary)
9	Cofactor
2	Crystallization (Commentary)
153	Disease/ Diagnostics
3	General Information
4	General Stability
41	Inhibitors
2	kcat/KM [mM/s]
23	KM Value [mM]
8	Localization
16	Metals/Ions
20	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
72	Organism
5	Pathway
19	PDB ID
9	pH Optimum
4	pH Range
1	pH Stability
1	Protein Variants
11	Purification (Commentary)
4	Reaction
3	Reaction Type
38	Reference
2	Renatured (Commentary)
2	Source Tissue
12	Specific Activity [micromol/min/mg]
5	Storage Stability
48	Substrates and Products (Substrate)
16	Subunits
43	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Range [°C]
8	Temperature Stability [°C]
5	Turnover Number [1/s]

pH Range

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pH Range on EC 1.6.1.1 - NAD(P)+ transhydrogenase (Si-specific)

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pH RANGE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

7 - 10.5

Escherichia coli

-

pH 7.0: about 55% of maximal activity, pH 10.5: about 45% of maximal activity

668061

7 - 9

Escherichia coli

P27306

more than 50% activity between pH 7.0 and 9.0

725040

8.4 - 8.7

Azotobacter vinelandii

-

half maximal activity in this pH range in the absence of Ca2+ or Mg2+, no activity above

392577

9.1 - 9.3

Azotobacter vinelandii

-

half maximal activity in this pH range in the presence of 5 mM Ca2+ or Mg2+, no activity above

392577