1.3.1.106: cobalt-precorrin-6A reductase
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Systematic Name
Systematic Name on EC 1.3.1.106 - cobalt-precorrin-6A reductase
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cobalt-precorrin-6B:NAD+ oxidoreductase
The enzyme, which participates in the anaerobic (early cobalt insertion) pathway of adenosylcobalamin biosynthesis, catalyses the reduction of the double bond between C-18 and C-19 of cobalt-precorrin-6A. The enzyme from the bacterium Bacillus megaterium has no activity with NADPH. See EC 1.3.1.54, precorrin-6A reductase, for the corresponding enzyme that participates in the aerobic cobalamin biosynthesis pathway.