1.1.3.45: aclacinomycin-N oxidase
This is an abbreviated version!
For detailed information about aclacinomycin-N oxidase, go to the full flat file.
Word Map on EC 1.1.3.45
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1.1.3.45
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sirtuins
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deacetylation
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nad+-dependent
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nicotinamide
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hyperacetylation
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mnsod
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caloric
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sirt3-dependent
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longevity
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sirt3-mediated
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sirts
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sirt1-7
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foxo3a
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acetylome
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honokiol
- 1.1.3.45
-
sirtuins
-
deacetylation
-
nad+-dependent
- nicotinamide
-
hyperacetylation
- mnsod
-
caloric
-
sirt3-dependent
-
longevity
-
sirt3-mediated
-
sirts
-
sirt1-7
-
foxo3a
-
acetylome
- honokiol
Reaction
Synonyms
aclacinomycin oxidoreductase, AknOx, dnrW
ECTree
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General Information
General Information on EC 1.1.3.45 - aclacinomycin-N oxidase
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malfunction
physiological function
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the bifunctional enzyme catalyzes the last two steps in the biosynthesis of polyketide antibiotics of the aclacinomycin group, the oxidation of the terminal sugar moiety rhodinose to cinerulose A and the oxidation of cinerulose A to L-aculose
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an enzyme deletion mutant shows partial loss in self-resistance against daunorubicin
malfunction
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an enzyme deletion mutant shows partial loss in self-resistance against daunorubicin
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